Published in EMBO J on December 01, 1991
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The transcription factor E2F-1 mediates the autoregulation of RB gene expression. Mol Cell Biol (1994) 1.73
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Phosphorylation-induced conformational changes in the retinoblastoma protein inhibit E2F transactivation domain binding. J Biol Chem (2010) 1.54
The product of the EMS1 gene, amplified and overexpressed in human carcinomas, is homologous to a v-src substrate and is located in cell-substratum contact sites. Mol Cell Biol (1993) 1.53
Low-penetrant RB allele in small-cell cancer shows geldanamycin instability and discordant expression with mutant ras. Cell Cycle (2008) 1.48
Deciphering the retinoblastoma protein phosphorylation code. Trends Biochem Sci (2012) 1.46
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Cumulative effect of phosphorylation of pRB on regulation of E2F activity. Mol Cell Biol (1999) 1.42
The retinoblastoma protein physically associates with the human cdc2 kinase. Mol Cell Biol (1992) 1.40
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Regulation of cell cycle progression and nuclear affinity of the retinoblastoma protein by protein phosphatases. Proc Natl Acad Sci U S A (1993) 1.38
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Structure-function analysis of the retinoblastoma tumor suppressor protein - is the whole a sum of its parts? Cell Div (2007) 1.22
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Cell cycle stage-specific phosphorylation of the Epstein-Barr virus immortalization protein EBNA-LP. J Virol (1996) 1.21
Nuclear protein phosphorylation and growth control. Biochem J (1992) 1.16
p38 phosphorylates Rb on Ser567 by a novel, cell cycle-independent mechanism that triggers Rb-Hdm2 interaction and apoptosis. Oncogene (2010) 1.06
Perturbation of the p53 response by human papillomavirus type 16 E7. J Virol (1997) 1.06
Quercetin-induced growth inhibition and cell death in prostatic carcinoma cells (PC-3) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression. J Cancer Res Clin Oncol (2005) 1.05
Mutations of N-terminal regions render the retinoblastoma protein insufficient for functions in development and tumor suppression. Mol Cell Biol (1997) 1.04
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The Rb family contains a conserved cyclin-dependent-kinase-regulated transcriptional repressor motif. Mol Cell Biol (1996) 0.97
Evidence for a mitochondrial localization of the retinoblastoma protein. BMC Cell Biol (2009) 0.95
Tumor promotion by caspase-resistant retinoblastoma protein. Proc Natl Acad Sci U S A (2005) 0.94
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Posttranslational modifications of the retinoblastoma tumor suppressor protein as determinants of function. Genes Cancer (2012) 0.93
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Lack of functional retinoblastoma protein mediates increased resistance to antimetabolites in human sarcoma cell lines. Proc Natl Acad Sci U S A (1995) 0.89
Gene network landscape of the ciliate Tetrahymena thermophila. PLoS One (2011) 0.88
Study of the role of retinoblastoma protein in terminal differentiation of murine erythroleukemia cells. Proc Natl Acad Sci U S A (1995) 0.88
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Site-specific hyperphosphorylation of pRb in HIV-induced neurotoxicity. Mol Cell Neurosci (2011) 0.87
Multiple mechanisms for E2F binding inhibition by phosphorylation of the retinoblastoma protein C-terminal domain. J Mol Biol (2013) 0.87
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The B-domain lysine patch of pRB is required for binding to large T antigen and release of E2F by phosphorylation. Mol Cell Biol (2002) 0.82
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The RB tumor suppressor positively regulates transcription of the anti-angiogenic protein NOL7. Neoplasia (2012) 0.76
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A Strategy for Direct Chemical Activation of the Retinoblastoma Protein. ACS Chem Biol (2016) 0.75
CDKL1 promotes tumor proliferation and invasion in colorectal cancer. Onco Targets Ther (2017) 0.75
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