Published in Nature on November 18, 1987
Isolation and direct complete nucleotide determination of entire genes. Characterization of a gene coding for 16S ribosomal RNA. Nucleic Acids Res (1989) 19.85
Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 15.69
Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet (2008) 13.95
Localization of type 1 diabetes susceptibility to the MHC class I genes HLA-B and HLA-A. Nature (2007) 6.67
Central role of defective interleukin-2 production in the triggering of islet autoimmune destruction. Immunity (2008) 6.08
Prime role for an insulin epitope in the development of type 1 diabetes in NOD mice. Nature (2005) 5.39
Molecular bases of dominant negative and loss of function mutations at the murine c-kit/white spotting locus: W37, Wv, W41 and W. EMBO J (1990) 5.08
HLA DR-DQ haplotypes and genotypes and type 1 diabetes risk: analysis of the type 1 diabetes genetics consortium families. Diabetes (2008) 4.94
Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro. Proc Natl Acad Sci U S A (1988) 4.40
Evidence for a primary association of celiac disease to a particular HLA-DQ alpha/beta heterodimer. J Exp Med (1989) 4.30
Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility. Proc Natl Acad Sci U S A (1988) 4.19
On the use of general control samples for genome-wide association studies: genetic matching highlights causal variants. Am J Hum Genet (2008) 3.95
Imputing amino acid polymorphisms in human leukocyte antigens. PLoS One (2013) 3.07
The glucose transporter family: structure, function and tissue-specific expression. Biochem J (1993) 3.00
The role of HLA class II genes in insulin-dependent diabetes mellitus: molecular analysis of 180 Caucasian, multiplex families. Am J Hum Genet (1996) 2.90
Genetic heterogeneity, modes of inheritance, and risk estimates for a joint study of Caucasians with insulin-dependent diabetes mellitus. Am J Hum Genet (1988) 2.88
CD226 Gly307Ser association with multiple autoimmune diseases. Genes Immun (2008) 2.76
HLA class II allelic variation and susceptibility to pemphigus vulgaris. Proc Natl Acad Sci U S A (1988) 2.72
Screen and clean: a tool for identifying interactions in genome-wide association studies. Genet Epidemiol (2010) 2.70
HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region. Proc Natl Acad Sci U S A (1989) 2.60
Detection of mRNA for the tax1/rex1 gene of human T-cell leukemia virus type I in fresh peripheral blood mononuclear cells of adult T-cell leukemia patients and viral carriers by using the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 2.49
Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene. Genome Res (2002) 2.45
Balancing immunity and tolerance: deleting and tuning lymphocyte repertoires. Proc Natl Acad Sci U S A (1996) 2.34
Induction and therapy of autoimmune diabetes in the non-obese diabetic (NOD/Lt) mouse by a 65-kDa heat shock protein. Proc Natl Acad Sci U S A (1990) 2.23
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A (1988) 2.19
The predisposition to type 1 diabetes linked to the human leukocyte antigen complex includes at least one non-class II gene. Am J Hum Genet (1999) 2.17
HLA-DR2 dose effect on susceptibility to multiple sclerosis and influence on disease course. Am J Hum Genet (2003) 2.02
Identification of multiple HTF-island associated genes in the human major histocompatibility complex class III region. EMBO J (1989) 1.97
Vaccination against autoimmune mouse diabetes with a T-cell epitope of the human 65-kDa heat shock protein. Proc Natl Acad Sci U S A (1991) 1.97
Wnt-3, a gene activated by proviral insertion in mouse mammary tumors, is homologous to int-1/Wnt-1 and is normally expressed in mouse embryos and adult brain. Proc Natl Acad Sci U S A (1990) 1.94
Confirmation of HLA class II independent type 1 diabetes associations in the major histocompatibility complex including HLA-B and HLA-A. Diabetes Obes Metab (2009) 1.94
Tissue-mediated control of immunopathology in coeliac disease. Nat Rev Immunol (2009) 1.91
Comprehensive characterization of MHC class II haplotypes in Mauritian cynomolgus macaques. Immunogenetics (2007) 1.87
Diabetogenic T cells recognize insulin bound to IAg7 in an unexpected, weakly binding register. Proc Natl Acad Sci U S A (2010) 1.87
The etiology of autoimmune thyroid disease: a story of genes and environment. J Autoimmun (2009) 1.81
Major histocompatibility complex genomics and human disease. Annu Rev Genomics Hum Genet (2013) 1.75
A diabetes-susceptible HLA haplotype is best defined by a combination of HLA-DR and -DQ alleles. J Clin Invest (1989) 1.72
Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J (2009) 1.70
Cytotoxic T cells specific for glutamic acid decarboxylase in autoimmune diabetes. J Exp Med (1995) 1.67
Genetic susceptibility to autoimmune thyroid disease: past, present, and future. Thyroid (2010) 1.67
Joint genetic susceptibility to type 1 diabetes and autoimmune thyroiditis: from epidemiology to mechanisms. Endocr Rev (2008) 1.66
HLA-DQ2 and -DQ8 signatures of gluten T cell epitopes in celiac disease. J Clin Invest (2006) 1.66
Genetic analysis of type 1 diabetes using whole genome approaches. Proc Natl Acad Sci U S A (1995) 1.66
HLA-DQ8 transgenic mice are highly susceptible to collagen-induced arthritis: a novel model for human polyarthritis. J Exp Med (1996) 1.66
Dendritic cells induce autoimmune diabetes and maintain disease via de novo formation of local lymphoid tissue. J Exp Med (1998) 1.65
Understanding type 1 diabetes through genetics: advances and prospects. Nat Rev Genet (2011) 1.64
Age-dependent HLA genetic heterogeneity of type 1 insulin-dependent diabetes mellitus. J Clin Invest (1992) 1.63
HLA genotyping in the international Type 1 Diabetes Genetics Consortium. Clin Trials (2010) 1.61
The HLA gene complex in thyroid autoimmunity: from epidemiology to etiology. J Autoimmun (2008) 1.61
Natural peptides selected by diabetogenic DQ8 and murine I-A(g7) molecules show common sequence specificity. J Clin Invest (2005) 1.60
Anti-IL-7 receptor-α reverses established type 1 diabetes in nonobese diabetic mice by modulating effector T-cell function. Proc Natl Acad Sci U S A (2012) 1.60
Follow-up analysis of genome-wide association data identifies novel loci for type 1 diabetes. Diabetes (2008) 1.56
A combination of HLA-DQ beta Asp57-negative and HLA DQ alpha Arg52 confers susceptibility to insulin-dependent diabetes mellitus. J Clin Invest (1990) 1.51
Electrostatic modifications of the human leukocyte antigen-DR P9 peptide-binding pocket and susceptibility to primary sclerosing cholangitis. Hepatology (2011) 1.51
Restricted islet-cell reactive T cell repertoire of early pancreatic islet infiltrates in NOD mice. Proc Natl Acad Sci U S A (2002) 1.49
Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse. J Exp Med (1994) 1.49
Seven regions of the genome show evidence of linkage to type 1 diabetes in a consensus analysis of 767 multiplex families. Am J Hum Genet (2001) 1.49
Oxidative stress biology and cell injury during type 1 and type 2 diabetes mellitus. Curr Neurovasc Res (2007) 1.48
The HLA Region and Autoimmune Disease: Associations and Mechanisms of Action. Curr Genomics (2007) 1.47
Selective binding of self peptides to disease-associated major histocompatibility complex (MHC) molecules: a mechanism for MHC-linked susceptibility to human autoimmune diseases. J Exp Med (1995) 1.46
Major histocompatibility complex class II molecules can protect from diabetes by positively selecting T cells with additional specificities. J Exp Med (1998) 1.44
Priming and effector dependence on insulin B:9-23 peptide in NOD islet autoimmunity. J Clin Invest (2007) 1.44
Allelic variants of the human putative peptide transporter involved in antigen processing. Proc Natl Acad Sci U S A (1992) 1.43
Affected-sib-pair mapping of a novel susceptibility gene to insulin-dependent diabetes mellitus (IDDM8) on chromosome 6q25-q27. Am J Hum Genet (1995) 1.42
Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families. Genes Immun (2009) 1.42
Self-reactive human CD4 T cell clones form unusual immunological synapses. J Exp Med (2012) 1.38
Putative amino acid sequence of HLA-DRB chain contributing to rheumatoid arthritis susceptibility. J Exp Med (1989) 1.37
Primarily chronic progressive and relapsing/remitting multiple sclerosis: two immunogenetically distinct disease entities. Proc Natl Acad Sci U S A (1989) 1.36
Distinct antibody specificities to a 64-kD islet cell antigen in type 1 diabetes as revealed by trypsin treatment. J Exp Med (1990) 1.36
Interrogating the major histocompatibility complex with high-throughput genomics. Hum Mol Genet (2012) 1.35
Identification of immunodominant T cell epitopes of human glutamic acid decarboxylase 65 by using HLA-DR(alpha1*0101,beta1*0401) transgenic mice. Proc Natl Acad Sci U S A (1997) 1.34
Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reaction. Proc Natl Acad Sci U S A (1998) 1.34
I-E+ nonobese diabetic mice develop insulitis and diabetes. J Exp Med (1993) 1.32
Crystal structure of HLA-DQ0602 that protects against type 1 diabetes and confers strong susceptibility to narcolepsy. Proc Natl Acad Sci U S A (2004) 1.29
Newborn HLA-DR,DQ genotype screening: age- and ethnicity-specific type 1 diabetes risk estimates. Pediatr Diabetes (2005) 1.28
T cell epitopes of insulin defined in HLA-DR4 transgenic mice are derived from preproinsulin and proinsulin. Proc Natl Acad Sci U S A (1998) 1.28
Prevention of diabetes in nonobese diabetic mice by anti-I-A monoclonal antibodies: transfer of protection by splenic T cells. Proc Natl Acad Sci U S A (1988) 1.26
Genetics of type 1 diabetes. Cold Spring Harb Perspect Med (2012) 1.25
Mechanistic insights into diabetes mellitus and oxidative stress. Curr Med Chem (2007) 1.25
Mutational hot spots in Ig V region genes of human follicular lymphomas. J Exp Med (1988) 1.25
Structural basis for major histocompatibility complex (MHC)-linked susceptibility to autoimmunity: charged residues of a single MHC binding pocket confer selective presentation of self-peptides in pemphigus vulgaris. Proc Natl Acad Sci U S A (1995) 1.24
High-resolution linkage mapping for susceptibility genes in human polygenic disease: insulin-dependent diabetes mellitus and chromosome 11q. Am J Hum Genet (1991) 1.23
CD8(+) T-cell autoreactivity to an HLA-B27-restricted self-epitope correlates with ankylosing spondylitis. J Clin Invest (2000) 1.23
Heterozygosity at individual amino acid sites: extremely high levels for HLA-A and -B genes. Proc Natl Acad Sci U S A (1991) 1.23
MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity. Front Immunol (2013) 1.22
Major histocompatibility complex class III genes and susceptibility to immunoglobulin A deficiency and common variable immunodeficiency. J Clin Invest (1992) 1.22
HLA DQ gene dosage and risk and severity of celiac disease. Clin Gastroenterol Hepatol (2007) 1.22
Regulation of major histocompatibility complex class II gene expression, genetic variation and disease. Genes Immun (2009) 1.21
Defining the transcriptional and cellular landscape of type 1 diabetes in the NOD mouse. PLoS One (2013) 1.21
Does intra-individual major histocompatibility complex diversity keep a golden mean? Philos Trans R Soc Lond B Biol Sci (2009) 1.20
Organ-specific and systemic autoimmune diseases originate from defects in hematopoietic stem cells. Proc Natl Acad Sci U S A (1990) 1.19
HLA-DQ primarily confers protection and HLA-DR susceptibility in type I (insulin-dependent) diabetes studied in population-based affected families and controls. Am J Hum Genet (1993) 1.19
Allelic diversification at the class II DQB locus of the mammalian major histocompatibility complex. Proc Natl Acad Sci U S A (1990) 1.18
In vivo evidence for the contribution of human histocompatibility leukocyte antigen (HLA)-DQ molecules to the development of diabetes. J Exp Med (2000) 1.17
Pathogenic CD4 T cells in type 1 diabetes recognize epitopes formed by peptide fusion. Science (2016) 1.17
An Abd transgene prevents diabetes in nonobese diabetic mice by inducing regulatory T cells. Proc Natl Acad Sci U S A (1993) 1.14
Definition of HLA-DQ as a transplantation antigen. Proc Natl Acad Sci U S A (1996) 1.14
Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients. J Clin Invest (1997) 1.14
Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans. Hum Mol Genet (2012) 1.14
Phenotypic analysis of antigen-specific T lymphocytes. Science (1996) 24.26
Histocompatibility-linked immune response genes. Science (1972) 16.79
Association study designs for complex diseases. Nat Rev Genet (2001) 8.91
Genetic control of specific immune responses. Adv Immunol (1969) 8.81
Genetic control of the antibody response. I. Demonstration of determinant-specific differences in response to synthetic polypeptide antigens in two strains of inbred mice. J Exp Med (1965) 7.27
HLA-E binds to natural killer cell receptors CD94/NKG2A, B and C. Nature (1998) 7.12
Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation. Proc Natl Acad Sci U S A (1997) 6.99
A new I subregion (I-J) marked by a locus (Ia-4) controlling surface determinants on suppressor T lymphocytes. J Exp Med (1976) 6.11
Limited heterogeneity of T cell receptors from lymphocytes mediating autoimmune encephalomyelitis allows specific immune intervention. Cell (1988) 5.73
HL-A, immune-response genes, and disease. Lancet (1974) 5.67
Th1 and Th2 CD4+ T cells in the pathogenesis of organ-specific autoimmune diseases. Immunol Today (1995) 5.32
Immune response to glutamic acid decarboxylase correlates with insulitis in non-obese diabetic mice. Nature (1993) 5.10
Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc Natl Acad Sci U S A (1992) 4.90
Two-gene control of the expression of a murine Ia antigen. J Exp Med (1978) 4.79
Genetic control of the antibody response: relationship between immune response and histocompatibility (H-2) type. Science (1969) 4.53
Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease. Lancet (1996) 4.33
Increased expression of CD44v6 and CD44v3 in ulcerative colitis but not colonic Crohn's disease. Lancet (1995) 4.12
Two stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12. Nat Genet (1996) 4.09
Genetic control of the immune response. Mapping of the Ir-1 locus. J Exp Med (1972) 3.96
Large clonal expansions of CD8+ T cells in acute infectious mononucleosis. Nat Med (1996) 3.94
A molecular basis for MHC class II--associated autoimmunity. Science (1988) 3.75
Identification and characterization of three members of the human SR family of pre-mRNA splicing factors. EMBO J (1995) 3.56
Genetic control of the antibody response in inbred mice. Transfer of response by spleen cells and linkage to the major histocompatibility (H-2) locus. J Exp Med (1968) 3.52
Tumour necrosis factor-alpha in murine autoimmune 'lupus' nephritis. Nature (1988) 3.46
A sensitive radioimmunoassay for detecting products translated from cloned DNA fragments. Cell (1978) 3.30
A genomewide scan for loci predisposing to type 2 diabetes in a U.K. population (the Diabetes UK Warren 2 Repository): analysis of 573 pedigrees provides independent replication of a susceptibility locus on chromosome 1q. Am J Hum Genet (2001) 3.26
Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors. J Virol (2000) 3.18
The localization of antigen in relation to specific antibody-producing cells. I. Use of a synthetic polypeptide [(T,G)-A--L] labelled with iodine-125. Immunology (1966) 3.09
Analysis of HLA-D region-associated molecules with monoclonal antibody. Proc Natl Acad Sci U S A (1979) 3.06
Genetic control of the immune response. The effect of thymectomy on the primary and secondary antibody response of mice to poly-L(tyr, glu)-poly-D, L-ala--poly-L-lys. J Exp Med (1972) 3.06
CD8(+) T cell-mediated spontaneous diabetes in neonatal mice. J Immunol (1996) 3.02
Selective expression of H-2 (i-region) loci controlling determinants on helper and suppressor T lymphocytes. J Exp Med (1976) 2.94
In vivo treatment of (NZB X NZW)F1 lupus-like nephritis with monoclonal antibody to gamma interferon. J Exp Med (1987) 2.93
Extensive conservation of alpha and beta chains of the human T-cell antigen receptor recognizing HLA-A2 and influenza A matrix peptide. Proc Natl Acad Sci U S A (1991) 2.90
Heritable major histocompatibility complex class II-associated differences in production of tumor necrosis factor alpha: relevance to genetic predisposition to systemic lupus erythematosus. Proc Natl Acad Sci U S A (1990) 2.88
The murine E alpha immune response gene. Cell (1983) 2.86
Detection of a common polypeptide chain in I--A and I--E sub-region immunoprecipitates. Mol Immunol (1979) 2.86
Endotoxin-induced uveitis in rats as a model for human disease. Nature (1980) 2.85
Several mechanisms can account for defective E alpha gene expression in different mouse haplotypes. Proc Natl Acad Sci U S A (1983) 2.84
Antigen recognition in autoimmune encephalomyelitis and the potential for peptide-mediated immunotherapy. Cell (1989) 2.77
The first external domain of the nonobese diabetic mouse class II I-A beta chain is unique. Proc Natl Acad Sci U S A (1987) 2.77
Histocompatibility (HL-A) antigens associated with systemic lupus erythematosus. A possible genetic predisposition to disease. N Engl J Med (1971) 2.69
Correlation of grain counts with radioactivity (125I and tritium) in autoradiography. Exp Cell Res (1966) 2.62
Protein clinical manifestations of primary tumors of the heart. Am J Med (1972) 2.61
HLA-DR4 subtype frequencies in rheumatoid arthritis indicate that DRB1 is the major susceptibility locus within the HLA class II region. Proc Natl Acad Sci U S A (1989) 2.60
Susceptibility to insulin dependent diabetes mellitus maps to a 4.1 kb segment of DNA spanning the insulin gene and associated VNTR. Nat Genet (1993) 2.56
Human HLA-A0201-restricted cytotoxic T lymphocyte recognition of influenza A is dominated by T cells bearing the V beta 17 gene segment. J Exp Med (1995) 2.55
Regions of allelic hypervariability in the murine A alpha immune response gene. Cell (1983) 2.53
Genetic control of the antibody response. II. Further analysis of the specificity of determinant-specific control, and genetic analysis of the response to (H,G)-A--L in CBA and C57 mice. J Exp Med (1967) 2.41
Crystal structure of the complex between human CD8alpha(alpha) and HLA-A2. Nature (1997) 2.41
Histocompatibility-linked genetic control of disease susceptibility. Murine lymphocytic choriomeningitis virus infection. J Exp Med (1973) 2.39
TCR binding to peptide-MHC stabilizes a flexible recognition interface. Immunity (1999) 2.33
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic process. J Exp Med (1994) 2.33
Persistent high frequency of human immunodeficiency virus-specific cytotoxic T cells in peripheral blood of infected donors. Proc Natl Acad Sci U S A (1995) 2.30
A sequential model for peptide binding and transport by the transporters associated with antigen processing. Immunity (1994) 2.26
Autoimmune diseases: the failure of self tolerance. Science (1990) 2.24
Aspartic acid at position 57 of the HLA-DQ beta chain protects against type I diabetes: a family study. Proc Natl Acad Sci U S A (1988) 2.19
Genetic and functional analysis of the Ia antigens: their possible role in regulating the immune response. Transplant Rev (1976) 2.15
Genetic control of the antibody response to poly-L(Tyr,Glu)-poly-D,L-Ala--poly-L-Lys in C3H--CWB tetraparental mice. J Exp Med (1974) 2.14
Variable synthesis and expression of E alpha and Ae (E beta) Ia polypeptide chains in mice of different H-2 haplotypes. Immunogenetics (1981) 2.13
Prevention of diabetes in nonobese diabetic mice by tumor necrosis factor (TNF): similarities between TNF-alpha and interleukin 1. Proc Natl Acad Sci U S A (1990) 2.13
A role for non-MHC genetic polymorphism in susceptibility to spontaneous autoimmunity. Immunity (1994) 2.09
The roles of Fas/APO-1 (CD95) and TNF in antigen-induced programmed cell death in T cell receptor transgenic mice. Immunity (1996) 2.05
T cell recognition as the target for immune intervention in autoimmune disease. Cell (1989) 2.04
Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain. J Biol Chem (1992) 2.03
HLA heterozygosity contributes to susceptibility to rheumatoid arthritis. Am J Hum Genet (1992) 2.03
In vivo effects of antibodies to immune response gene products: prevention of experimental allergic encephalitis. Proc Natl Acad Sci U S A (1981) 2.00
T cell receptor and coreceptor CD8 alphaalpha bind peptide-MHC independently and with distinct kinetics. Immunity (1999) 1.98
Increased frequency of HLA-Cw3 and HLA-Dw4 in rheumatoid arthritis. Arthritis Rheum (1977) 1.95
Genetic control of the antibody response. 3. Qualitative and quantitative characterization of the antibody response to (T,G)-A--L in CBA and C57 mice. J Immunol (1968) 1.94
Insulin-dependent diabetes mellitus: the initial lesion. N Engl J Med (1981) 1.93
CD8highCD57+ T lymphocytes in normal, healthy individuals are oligoclonal and respond to human cytomegalovirus. J Immunol (1995) 1.92
Allelic variation in the DR subregion of the human major histocompatibility complex. Proc Natl Acad Sci U S A (1987) 1.92
Chronic tumor necrosis factor alters T cell responses by attenuating T cell receptor signaling. J Exp Med (1997) 1.92
Predominant expression of a T cell receptor V beta gene subfamily in autoimmune encephalomyelitis. J Exp Med (1988) 1.89
Intravenous injection of soluble antigen induces thymic and peripheral T-cells apoptosis. Proc Natl Acad Sci U S A (1996) 1.85
The genetics of inflammatory bowel disease. Gut (1997) 1.83
BirA enzyme: production and application in the study of membrane receptor-ligand interactions by site-specific biotinylation. Anal Biochem (1999) 1.81
Treatment of (NZB x NZW)F1 disease with anti-I-A monoclonal antibodies. J Exp Med (1983) 1.79
Genetics of inflammatory bowel disease. Gut (1994) 1.79
CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. J Immunol (1997) 1.79
Isolation of a cDNA encoding the human CD38 (T10) molecule, a cell surface glycoprotein with an unusual discontinuous pattern of expression during lymphocyte differentiation. J Immunol (1990) 1.78
The nature of the antigenic determinant in a genetic control of the antibody response. J Exp Med (1969) 1.74
Characterization of HLA-D-region antigens by two-dimensional gel electrophoresis. Molecular-genotyping. J Exp Med (1980) 1.73
Variation in human T cell receptor V beta and J beta repertoire: analysis using anchor polymerase chain reaction. Eur J Immunol (1992) 1.73
Disrupted splenic architecture, but normal lymph node development in mice expressing a soluble lymphotoxin-beta receptor-IgG1 fusion protein. Proc Natl Acad Sci U S A (1996) 1.71
The murine Ia alpha chains, E alpha and A alpha, show a surprising degree of sequence homology. Proc Natl Acad Sci U S A (1983) 1.69
TRICK2, a new alternatively spliced receptor that transduces the cytotoxic signal from TRAIL. Curr Biol (1997) 1.68
Gene conversion between murine class II major histocompatibility complex loci. Functional and molecular evidence from the bm 12 mutant. J Exp Med (1984) 1.66
Conservation of T cell receptor usage by HLA B27-restricted influenza-specific cytotoxic T lymphocytes suggests a general pattern for antigen-specific major histocompatibility complex class I-restricted responses. Eur J Immunol (1993) 1.65
Proteoglycan forms of the lymphocyte homing receptor CD44 are alternatively spliced variants containing the v3 exon. J Cell Biol (1995) 1.65
Mapping of the class II region of the human major histocompatibility complex by pulsed-field gel electrophoresis. Nature (1986) 1.64
A functional polymorphism of the stromelysin gene (MMP-3) influences susceptibility to primary sclerosing cholangitis. Gastroenterology (2001) 1.60
The human CD8 coreceptor effects cytotoxic T cell activation and antigen sensitivity primarily by mediating complete phosphorylation of the T cell receptor zeta chain. J Biol Chem (2001) 1.59
LARD: a new lymphoid-specific death domain containing receptor regulated by alternative pre-mRNA splicing. Proc Natl Acad Sci U S A (1997) 1.58
The genetic control of antibody specificity. J Exp Med (1969) 1.58
Structure of murine Ia antigens: partial NH2-terminal amino acid sequences of products of the I-E or I-C subregion. Proc Natl Acad Sci U S A (1977) 1.56
HLA-DR and HLA-DP genotypes and immunoglobulin E responses to common major allergens. Clin Exp Allergy (1994) 1.56