Published in Proc Natl Acad Sci U S A on January 01, 1973
Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis. J Virol (1974) 23.54
Processing of adenovirus 2-induced proteins. J Virol (1973) 12.52
A method for the recovery of DNA from agarose gels. Nucleic Acids Res (1978) 6.24
Unique DNA associated with mitochondria in the "S"-type cytoplasm of male-sterile maize. Proc Natl Acad Sci U S A (1977) 5.05
Isolation of DNA from agarose gels using DEAE-paper. Application to restriction site mapping of adenovirus type 16 DNA. Nucleic Acids Res (1980) 4.64
Mapping of late adenovirus genes by cell-free translation of RNA selected by hybridization to specific DNA fragments. Proc Natl Acad Sci U S A (1975) 4.35
Unique double-stranded fragments of bacteriophage T5 DNA resulting from preferential shear-induced breakage at nicks. Proc Natl Acad Sci U S A (1974) 4.31
Adenovirus DNA-directed transcription of 5.5S RNA in vitro. Proc Natl Acad Sci U S A (1978) 4.01
Molecular cloning of extensive sequences of the in vitro synthesized chicken ovalbumin structural gene. Nucleic Acids Res (1977) 3.32
Structure and composition of the adenovirus type 2 core. J Virol (1975) 3.21
DNA of Epstein-Barr virus. I. Comparative studies of the DNA of Epstein-Barr virus from HR-1 and B95-8 cells: size, structure, and relatedness. J Virol (1975) 3.13
Transcription of simian virus 40. 3. Mapping of "early" and "late" species of RNA. Proc Natl Acad Sci U S A (1973) 3.04
Structure of Herpesvirus saimiri genomes: arrangement of heavy and light sequences in the M genome. J Virol (1976) 2.87
Heterogeneity of Epstein-Barr virus. III. Comparison of a transforming and a nontransforming virus by partial denaturation mapping of their DNAs. J Virol (1978) 2.78
Structure and molecular weight of the 60-70S RNA and the 30-40S RNA of the Rous sarcoma virus. Proc Natl Acad Sci U S A (1974) 2.60
Relationship of mRNA from productively infected cells to the complementary strands of adenovirus type 2 DNA. J Virol (1974) 2.52
Physical mapping of a large-plaque mutation of adenovirus type 2. J Virol (1979) 2.50
Cleavage of Epstein-Barr virus DNA by restriction endonucleases EcoRI, HindIII and BamI. Nucleic Acids Res (1978) 2.50
Apparent Involvement of a Plasmid in Phaseotoxin Production by Pseudomonas phaseolicola. Appl Environ Microbiol (1979) 2.49
State and organization of polyoma virus DNA sequences in transformed rat cell lines. J Virol (1979) 2.47
Adenovirus-2 mRNA is transcribed as part of a high-molecular-weight precursor RNA. Proc Natl Acad Sci U S A (1975) 2.28
Structure of nonintegrated, circular Herpesvirus saimiri and Herpesvirus ateles genomes in tumor cell lines and in vitro-transformed cells. J Virol (1982) 2.23
Physical map of the BK virus genome. J Virol (1975) 2.18
Transcription of the genome of adenovirus type 12. III. Maps of stable RNA from productively infected human cells and abortively infected and transformed hamster cells. J Virol (1976) 2.12
Block to multiplication of adenovirus serotype 2 in monkey cells. J Virol (1975) 2.10
Conditional lethal mutants of adenovirus 2-simian virus 40 hybrids. I. Host range mutants of Ad2+ND1. J Virol (1974) 2.08
Characterization of Aleutian disease virus as a parvovirus. J Virol (1980) 2.04
Episomal viral DNA in a Herpesvirus saimiri-transformed lymphoid cell line. J Virol (1977) 1.93
Infectious, linear, unintegrated DNA of Moloney murine leukemia virus. J Virol (1976) 1.91
Characterization of human papovavirus BK DNA. J Virol (1975) 1.81
Analysis of early adenovirus 2 RNA using Eco R-R1 viral DNA fragments. J Virol (1975) 1.80
Chromatin-like organization of the adenovirus chromosome. Proc Natl Acad Sci U S A (1976) 1.79
Circular Epstein-Barr virus genomes of reduced size in a human lymphoid cell line of infectious mononucleosis origin. J Virol (1977) 1.77
Synthesis of complementary RNA sequences during productive adenovirus infection. Proc Natl Acad Sci U S A (1974) 1.70
Kinetic studies on the cleavage of adenovirus DNA by restriction endonuclease Eco RI. Nucleic Acids Res (1976) 1.64
Study of the fine structure of adeno-associated virus DNA with bacterial restriction endonucleases. J Virol (1975) 1.60
Herpesvirus papio DNA is similar in organization to Epstein-Barr virus DNA. J Virol (1981) 1.54
Herpesvirus ateles DNA and its homology with Herpesvirus saimiri nucleic acid. J Virol (1978) 1.53
Physical organization of subgroup B human adenovirus genomes. J Virol (1977) 1.51
Protection of particular cleavage sites of restriction endonucleases by distamycin A and actinomycin D. Nucleic Acids Res (1976) 1.47
Localization of adenovirus 2 messenger RNA's to segments of the viral genome defined by endonuclease R-R1. Proc Natl Acad Sci U S A (1974) 1.47
Inverted repeat nucleotide sequences in the genomes of Marek disease virus and the herpesvirus of the turkey. Proc Natl Acad Sci U S A (1982) 1.39
Specific fragmentation of DNA of adenovirus serotypes 3, 5, 7, and 12, and adeno-simian virus 40 hybrid virus Ad2+ND1 by restriction endonuclease R.EcoRI. J Virol (1974) 1.39
Adenovirus type 2 late mRNA's: structural evidence for 3'-coterminal species. J Virol (1978) 1.37
Two classes of cytoplasmic viral RNA synthesized early in productive infection with adenovirus 2. J Virol (1974) 1.37
Genome structure and virion polypeptides of the primate herpesviruses Herpesvirus aotus types 1 and 3: comparison with human cytomegalovirus. J Virol (1983) 1.32
Localization of single-chain interruptions in bacteriophage T5 DNA I. Electron microscopic studies. J Virol (1977) 1.32
Adenovirus transcription. II. RNA sequences complementary to simian virus 40 and adenovirus 2DNA in AD2+ND1- and AD2+ND3-infected cells. J Virol (1975) 1.28
Cleavage of lambda DNA by a site-specific endonuclease from Serratia marcescens. J Virol (1976) 1.27
Termination sites for adenovirus type 2 DNA replication. J Virol (1975) 1.25
The length of the terminal repetition in adenovirus-2 DNA. Proc Natl Acad Sci U S A (1974) 1.25
Intracellular forms of adenovirus DNA: integrated form of adenovirus DNA appears early in productive infection. Proc Natl Acad Sci U S A (1976) 1.22
Studies of polyoma virus DNA: cleavage map of the polyoma virus genome. J Virol (1975) 1.20
Structure of the inverted terminal repetition of adenovirus type 2 DNA. J Virol (1977) 1.20
Characterization of the DNA of a Nonoccluded Baculovirus, Hz-1V. J Virol (1982) 1.19
Use of a restriction endonuclease in analyzing the genomes from two different strains of vaccinia virus. J Virol (1976) 1.17
Cell-free translation of highly purified adenovirus messenger RNA. Proc Natl Acad Sci U S A (1974) 1.12
Identification of early adenovirus type 2 RNA species transcribed from the left-hand end of the genome. J Virol (1975) 1.11
mRNA from the transforming segment of the adenovirus 2 genome in productively infected and transformed cells. J Virol (1976) 1.11
A site-specific single-strand endonuclease from the eukaryote Chlamydomonas. Proc Natl Acad Sci U S A (1977) 1.10
Unusual Baculovirus of the Parasitoid Wasp Apanteles melanoscelus: Isolation and Preliminary Characterization. J Virol (1979) 1.09
Intermediate in adenovirus type 2 replication. J Virol (1975) 1.03
Biochemical studies on bovine adenovirus type 3. I. Purification and properties. J Virol (1975) 1.03
Linkage map of the fragments of herpesvirus papio DNA. J Virol (1981) 1.01
The 3'-terminal nucleotide sequences of adenovirus types 2 and 5 DNA. J Virol (1975) 0.99
Restriction endonuclease cleavage map of mitochondrial DNA from Aspergillus nidulans. Nucleic Acids Res (1978) 0.97
Biochemical studies on bovine adenovirus type 3. III. Cleavage maps of viral DNA by restriction endoncleases EcoRI, BamHI, and HindIII. J Virol (1978) 0.94
Transcription map for adenovirus type 12 DNA. J Virol (1978) 0.94
Adenovirus type 2 DNA replication. I. Evidence for discontinuous DNA synthesis. J Virol (1975) 0.92
Sequence relationships between adenovirus 2 early RNA and viral RNA size classes synthesized at 18 hours after infection. J Virol (1975) 0.92
Analysis of polyoma virus DNA replicative intermediates by agarose gel electrophoresis. J Virol (1977) 0.90
Reassociation of complementary strand-specific adenovirus type 2 DNA with viral DNA sequences of transformed cells. J Virol (1977) 0.88
Differential accumulation of virus-specific RNA during the cell cycle of adenovirus-transformed rat embyro cells. J Virol (1975) 0.85
Mapping and cloning of Eco RI-fragments of bacteriophage T5+ DNA. Nucleic Acids Res (1977) 0.84
Multiple origins and circular structures in replicating T5 bacteriophage DNA. J Virol (1976) 0.84
Adenovirus type 2 nuclear RNA accumulating during productive infection. J Virol (1977) 0.81
Genome structure of cottontail rabbit herpesvirus. J Virol (1989) 0.79
Molecular weight determination program. Nucleic Acids Res (1984) 0.79
Sites of cleavage by restriction enzymes in viral DNAs: comparison of observed and expected frequencies. Nucleic Acids Res (1974) 0.75
Kinetics of renaturation of DNA. J Mol Biol (1968) 25.41
Molecular weight estimation and separation of ribonucleic acid by electrophoresis in agarose-acrylamide composite gels. Biochemistry (1968) 21.08
DNA nucleotide sequence restricted by the RI endonuclease. Proc Natl Acad Sci U S A (1972) 15.71
Cleavage of DNA by R 1 restriction endonuclease generates cohesive ends. Proc Natl Acad Sci U S A (1972) 13.95
Specific cleavage of simian virus 40 DNA by restriction endonuclease of Hemophilus influenzae. Proc Natl Acad Sci U S A (1971) 10.06
Cleavage of Simian virus 40 DNA at a unique site by a bacterial restriction enzyme. Proc Natl Acad Sci U S A (1972) 8.96
Molecular weights of coliphages and coliphage DNA. IV. Molecular weights of DNA from bacteriophages T4, T5 and T7 and the general problem of determination of M. J Mol Biol (1970) 8.47
Specificity of the break produced by restricting endonuclease R 1 in Simian virus 40 DNA, as revealed by partial denaturation mapping. Proc Natl Acad Sci U S A (1972) 6.87
Biochemical studies on adenovirus multiplication. IV. Isolation, purification, and chemical analysis of adenovirus. Virology (1963) 6.75
DNA of bacteriophage PM2: a closed circular double-stranded molecule. Proc Natl Acad Sci U S A (1969) 6.47
Adenovirus DNA. I. Molecular weight and conformation. Proc Natl Acad Sci U S A (1967) 5.55
Adenovirus-2 DNA contains an inverted terminal repetition. Proc Natl Acad Sci U S A (1972) 4.57
A unique form of terminal redundancy in adenovirus DNA molecules. Proc Natl Acad Sci U S A (1972) 4.18
Early events of virus-cell interaction in an adenovirus system. J Virol (1969) 3.68
Denaturation pattern of the DNA of adenovirus type 2 as determined by electron microscopy. J Mol Biol (1970) 3.35
Structural proteins of adenoviruses. IV. Sequential degradation of the adenovirus type 2 virion. Virology (1970) 2.65
Transformation of primary rat embryo cells by adenovirus type 2. Proc Natl Acad Sci U S A (1967) 2.53
Structural proteins of adenoviruses. I. Purification and characterization of the adenovirus type 2 hexon antigen. Virology (1967) 2.25
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry (1973) 43.61
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell (1985) 10.06
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
Recognition of cap structure in splicing in vitro of mRNA precursors. Cell (1984) 8.67
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
Tracking of childhood overweight into adulthood: a systematic review of the literature. Obes Rev (2008) 8.42
Amount of viral DNA in the genome of cells transformed by adenovirus type 2. J Mol Biol (1973) 8.28
Speculations on RNA splicing. Cell (1981) 8.28
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell (1986) 8.06
Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell (1988) 8.00
Studies on in vitro transformation by DNA and DNA fragments of human adenoviruses and simian virus 40. Cold Spring Harb Symp Quant Biol (1975) 7.76
Splicing of messenger RNA precursors. Science (1987) 7.61
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol Cell Biol (1986) 7.49
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes. Cell (1987) 7.44
Regulation by HIV Rev depends upon recognition of splice sites. Cell (1989) 7.13
In vitro transcription of adenovirus. J Virol (1981) 7.06
Specificity of the break produced by restricting endonuclease R 1 in Simian virus 40 DNA, as revealed by partial denaturation mapping. Proc Natl Acad Sci U S A (1972) 6.87
Structure of two spliced mRNAs from the transforming region of human subgroup C adenoviruses. Nature (1979) 6.60
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
Evolutionary fates and origins of U12-type introns. Mol Cell (1998) 6.25
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (1992) 5.87
Human CCAAT-binding proteins have heterologous subunits. Cell (1988) 5.81
A high-efficiency HeLa cell nuclear transcription extract. DNA (1988) 5.81
The gene for polypeptide IX of adenovirus type 2 and its unspliced messenger RNA. Cell (1980) 5.80
Severe psoriasis--oral therapy with a new retinoid. Dermatologica (1978) 5.67
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science (1984) 5.11
Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Mol Cell Biol (1987) 5.05
Mapping of adenovirus 2 RNA sequences in lytically infected cells and transformed cell lines. Cold Spring Harb Symp Quant Biol (1975) 4.87
Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. Proc Natl Acad Sci U S A (1988) 4.83
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis. J Virol (1984) 4.72
Separation and characterization of factors mediating accurate transcription by RNA polymerase II. J Biol Chem (1982) 4.71
On the origin of RNA splicing and introns. Cell (1985) 4.70
Virus-receptor interaction in an adenovirus system. J Virol (1968) 4.69
Sequence heterogeneity in closed simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.69
Splicing of adenovirus RNA in a cell-free transcription system. Proc Natl Acad Sci U S A (1983) 4.69
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature (1982) 4.42
Viral DNA in transformed cells. I. A study of the sequences of adenovirus 2 DNA in a line of transformed rat cells using specific fragments of the viral genome. J Mol Biol (1974) 4.30
HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J (1991) 4.18
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev (1988) 4.14
In vitro transcription: whole-cell extract. Methods Enzymol (1983) 4.07
Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome. Science (1986) 4.01
Messenger RNA splicing in vitro: an excised intervening sequence and a potential intermediate. Cell (1984) 4.00
An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene (1977) 3.94
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
Characterization of HIV-1 neutralization escape mutants. AIDS (1989) 3.88
Cleavage maps of DNA from adenovirus types 2 and 5 by restriction endonucleases EcoRI and HpaI. Cold Spring Harb Symp Quant Biol (1975) 3.87
Transcription maps of adenovirus. Methods Enzymol (1980) 3.82
DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. Cell (1993) 3.77
RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A (1979) 3.75
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Site-specific polyadenylation in a cell-free reaction. Cell (1984) 3.59
HIV-1 Tat protein trans-activates transcription in vitro. Cell (1990) 3.57
Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev (1991) 3.55
SV40 DNA transfection of cells in suspension: analysis of efficiency of transcription and translation of T-antigen. Gene (1981) 3.54
Interactions between RNA polymerase II, factors, and template leading to accurate transcription. J Biol Chem (1984) 3.47
Structure of genes for virus-associated RNAI and RNAII of adenovirus type 2. Proc Natl Acad Sci U S A (1980) 3.45
Exon amplification: a strategy to isolate mammalian genes based on RNA splicing. Proc Natl Acad Sci U S A (1991) 3.43
The octamer-binding proteins form multi-protein--DNA complexes with the HSV alpha TIF regulatory protein. EMBO J (1989) 3.42
Spliceosome assembly involves the binding and release of U4 small nuclear ribonucleoprotein. Proc Natl Acad Sci U S A (1988) 3.38
Evidence for two active sites in the spliceosome provided by stereochemistry of pre-mRNA splicing. Nature (1993) 3.36
Generation of adenovirus by transfection of plasmids. Nucleic Acids Res (1983) 3.33
Structural proteins of adenoviruses. X. Isolation and topography of low molecular weight antigens from the virion of adenovirus type 2. Virology (1973) 3.26
A hyperphosphorylated form of the large subunit of RNA polymerase II is associated with splicing complexes and the nuclear matrix. Proc Natl Acad Sci U S A (1996) 3.25
Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell lines. Proc Natl Acad Sci U S A (1979) 3.24
Isolation of the gene encoding the yeast TATA binding protein TFIID: a gene identical to the SPT15 suppressor of Ty element insertions. Cell (1989) 3.18
Yeast TATA-binding protein TFIID binds to TATA elements with both consensus and nonconsensus DNA sequences. Proc Natl Acad Sci U S A (1989) 3.18
Regulation of heat shock protein 70 gene expression by c-myc. Nature (1984) 3.18
Nucleotide sequence and evolution of a mammalian alpha-tubulin messenger RNA. J Mol Biol (1981) 3.18
Characterization of the branch site in lariat RNAs produced by splicing of mRNA precursors. Nature (1985) 3.17
Amplification and expression of sequences cotransfected with a modular dihydrofolate reductase complementary dna gene. J Mol Biol (1982) 3.17
The infectivity of adenovirus 5 DNA-protein complex. Virology (1976) 3.12
Structural analysis of the interaction between the human immunodeficiency virus Rev protein and the Rev response element. Proc Natl Acad Sci U S A (1991) 3.06
Transcription of simian virus 40. 3. Mapping of "early" and "late" species of RNA. Proc Natl Acad Sci U S A (1973) 3.04
A coactivator of pre-mRNA splicing. Genes Dev (1998) 3.04
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Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif. Science (1988) 3.01