Published in J Exp Med on September 01, 1978
Induction of tolerance in influenza virus-immune T lymphocyte clones with synthetic peptides of influenza hemagglutinin. J Exp Med (1983) 3.52
Involvement of endogenous tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice. Proc Natl Acad Sci U S A (1992) 2.73
The induction of cell-mediated immunity and tolerance with protein antigens coupled to syngeneic lymphoid cells. J Exp Med (1979) 2.09
Clonal anergy: persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc Natl Acad Sci U S A (1980) 2.04
The injection of deaggregated gamma globulins in adult mice induces antigen-specific unresponsiveness of T helper type 1 but not type 2 lymphocytes. J Exp Med (1992) 1.32
Tolerogenicity of resting and activated B cells. J Exp Med (1994) 1.25
Tolerance induction during ontogeny. I. Presence of active suppression in mice rendered tolerant to human gamma-globulin in utero correlates with the breakdown of the tolerant state. J Exp Med (1979) 1.18
Suppressor T cell memory. II. The role of memory suppressor T cells in tolerance to human gamma globulin. J Exp Med (1983) 1.14
A natural model of immunologic tolerance. Tolerance to murine C5 is mediated by T cells, and antigen is required to maintain unresponsiveness. J Exp Med (1982) 1.04
Induction and mode of action of suppressor cells generated against human gamma globulin. II. Effects of colchicine. J Exp Med (1979) 0.94
Current perspectives on the cellular mechanisms of immunologic tolerance. Clin Exp Immunol (1980) 0.85
Dichotomy between the induction of suppressor cells and immunologic tolerance by adult thymectomy. J Exp Med (1980) 0.82
Tolerance for self IG at the level of the Ly1+ T cell. J Exp Med (1983) 0.78
Deregulation of idiotype expression. Induction of tolerance in an anti-idiotypic response. J Exp Med (1982) 0.77
Strain-dependent protective effect of adult thymectomy on murine infection by Mycobacterium lepraemurium. Clin Exp Immunol (1987) 0.77
Immunological tolerance in vitro: a review. J R Soc Med (1984) 0.75
Immunization of dissociated spleen cell cultures from normal mice. J Exp Med (1967) 30.93
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
T cell-dependent suppression of an anti-hapten antibody response. Transplant Rev (1975) 3.06
A disquisition on suppressor T cells. Transplant Rev (1975) 3.04
Ly and Ia antigen phenotypes of T cells involved in delayed-type hypersensitivity and in suppression. J Exp Med (1976) 3.00
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Enrichment of specific suppressor T cells and characterization of their surface markers. J Exp Med (1977) 2.13
Different functional specificity repertoires for suppressor and helper T cells. Immunol Rev (1978) 1.91
Regulation of immune responses by suppressor T cells. Tohoku J Exp Med (1976) 1.73
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
The role of soluble aggregates in the primary immune response of mice to human gamma globulin. Int Arch Allergy Appl Immunol (1966) 1.54
The role of specific suppressor T cells in immune tolerance. Transplant Rev (1975) 1.50
Spleen cells from animals tolerant to a thymus-dependent antigen can be activated by lipopolysaccharide to synthesize antibodies against the tolerogen. J Exp Med (1976) 1.48
Specific suppression of the immune response by HGG tolerant spleen cells. I. Parameters affecting the level of suppression. J Immunol (1976) 1.30
Specific, transient suppression of the immune response by HGG tolerant spleen cells. II. Effector cells and target cells. J Immunol (1976) 1.14
Neonatally induced tolerance to HGG: duration in B cells and absence of specific suppressor cells. J Immunol (1977) 1.10
Suppressor T-cell memory. Nature (1978) 1.10
Specific suppression of the immune response by a factor obtained from spleen cells of mice tolerant to human gamma-globulin. J Immunol (1978) 1.09
Possible roles of suppressor cells in immunologic tolerance. Transplant Rev (1975) 1.07
Induction of immunological tolerance requires that the B cells can respond to the polyclonal B-cell-activating properties of the thymus-independent antigens. J Exp Med (1977) 1.06
Suppressor T cells in tolerance to non-self and self antigens. Cold Spring Harb Symp Quant Biol (1977) 1.03
Effect of lipopolysaccharide on immunogenicity and tolerogenicity of HGG in C57BL/6J nude mice: evidence for a possible B cell deficiency. J Immunol (1977) 1.02
Interaction of K lymphocytes with myeloma proteins of different IgG subclasses. J Immunol (1976) 0.99
Tolerance induction to a hapten protein conjugate in vivo: are suppressor T cells involved. Eur J Immunol (1974) 0.96
Suppressor cells in tolerance to HGG: kinetics and cross-suppression in high dose tolerance--absence in low dose tolerance. J Immunol (1977) 0.91
Induction of tolerance in athymic mice with an antigen which is highly immunogenic in euthymic mice. Cell Immunol (1977) 0.90
Immunologic tolerance to HGG in mice. I. Suppression of the HGG response in normal mice with spleen cells or a spleen cell lysate from tolerant mice. J Immunol (1977) 0.90
Restoration of immune competence in tolerant mice by parabiosis to normal mice. J Exp Med (1974) 0.86
A network theory of the immune system. Eur J Immunol (1975) 0.85
Suppressor T cells in tolerance to human gamma-globulin: mediation by a specific soluble factor. Cell Immunol (1978) 0.81
Quantitation of mRNA by the polymerase chain reaction. Proc Natl Acad Sci U S A (1989) 15.69
Kinetic differences in unresponsiveness of thymus and bone marrow cells. Science (1971) 4.13
A modification of the hemolytic plaque assay for use with protein antigens. J Immunol (1968) 4.02
Regulation of integrin function by the urokinase receptor. Science (1996) 3.56
Immunoglobulins cytophilic for human lymphocytes, monocytes, and neutrophils. J Clin Invest (1975) 3.39
Immunologic properties of bacterial lipopolysaccharide (LPS): correlation between the mitogenic, adjuvant, and immunogenic activities. J Immunol (1975) 3.18
Cellular sites of immunologic unresponsiveness. Proc Natl Acad Sci U S A (1970) 3.01
Immunological unresponsiveness. Adv Immunol (1973) 2.75
Relationship of the structure of bacterial lipopolysaccharides to its function in mitogenesis and adjuvanticity. Proc Natl Acad Sci U S A (1973) 2.61
Patterns of cytokine gene expression by CD4+ T cells from young and old mice. J Immunol (1993) 2.56
Recent observations and concepts in immunological unresponsiveness and autoimmunity. Clin Exp Immunol (1971) 2.45
Analysis of autoimmunity through experimental models of thyroiditis and allergic encephalomyelitis. Adv Immunol (1980) 2.27
Immunologic properties of bacterial lipopolysaccharide (LPS). II. The unresponsiveness of C3H/HeJ Mouse spleen cells to LPS-induced mitogenesis is dependent on the method used to extract LPS. J Exp Med (1975) 2.22
Termination of tolerance to human gamma globulin in mice by antigen and bacterial lipopolysaccharide (endotoxin). J Exp Med (1973) 2.15
Transfer of experimental autoimmune thyroiditis by serum from thyroidectomized donors. J Exp Med (1969) 2.12
The production of thyroiditis and antibody following injection of unaltered thyroglobulin without adjuvant into rabbits previously stimulated with altered thyroglobulin. J Exp Med (1965) 1.96
Interactions between viruses and lymphocytes. I. In vivo replication of lymphocytic choriomeningitis virus in mononuclear cells during both chronic and acute viral infections. J Immunol (1978) 1.95
The age-associated increase in IFN-gamma synthesis by mouse CD8+ T cells correlates with shifts in the frequencies of cell subsets defined by membrane CD44, CD45RB, 3G11, and MEL-14 expression. J Immunol (1993) 1.88
The production of antisera to human gammaGlobulin subclasses in rabbits using immunological unresponsiveness. J Immunol (1968) 1.82
Studies on the induction of immunologic unresponsiveness. 3. Antigen form and mouse strain variation. J Immunol (1969) 1.81
Differences in the expression profiles of CD45RB, Pgp-1, and 3G11 membrane antigens and in the patterns of lymphokine secretion by splenic CD4+ T cells from young and aged mice. J Immunol (1990) 1.79
Cellular events during induction of immunologic unresponsiveness in adult mice. J Immunol (1971) 1.72
Studies on the induction of immunologic unresponsiveness. II. Kinetics. J Immunol (1967) 1.70
Cellular events in the induction of experimental allergic encephalomyelitis in rats. J Exp Med (1976) 1.69
The cellular and subcellular bases of immunosenescence. Adv Immunol (1989) 1.59
B-lymphocytes activation by the Fc region of IgG. J Exp Med (1977) 1.51
Cyclical production of antibody as a regulatory mechanism in the immune response. Adv Immunol (1975) 1.50
The ability of bacterial lipopolysaccharide to modulate the induction of unresponsiveness to a state of immunity. Cellular parameters. J Exp Med (1973) 1.49
Interstitial immune complex thyroiditis in mice: the role of autoantibody to thyroglobulin. J Exp Med (1974) 1.49
Lymphokines and aging: interleukin-2 production and activity in aged animals. J Immunol (1981) 1.48
Studies on the induction of immunologic unresponsiveness. I. Effects of endotoxin and phytochemagglutinin. J Immunol (1967) 1.47
Effect of immunological unresponsiveness on different cell populations. Transplant Rev (1972) 1.45
Regulation of immune response by components of the complement cascade and their activated fragments. Springer Semin Immunopathol (1983) 1.41
Roles of T and B lymphocytes in the termination of unresponsiveness to autologous thyroglobulin in mice. J Exp Med (1974) 1.38
Nonspecific activation of murine lymphocytes. I. Proliferation and polyclonal activation induced by 2-mercaptoethanol and alpha-thioglycerol. J Exp Med (1977) 1.37
Effect of chronic viral infection on the immune system. I. Comparison of the immune responsiveness of mice chronically infected with LCM virus with that of noninfected mice. J Immunol (1973) 1.36
The development of autoimmune thyroiditis in rabbits following injection of aqueous preparations of heterologous thyroglobulins. J Immunol (1967) 1.35
Induction of interleukin 1 secretion and enhancement of humoral immunity by binding of human C5a to macrophage surface C5a receptors. J Exp Med (1982) 1.35
Immunologic properties of bacterial lipopolysaccharide (LPS). III. Genetic linkage between the in vitro mitogenic and in vivo adjuvant properties of LPS. J Exp Med (1976) 1.34
Cell-mediated immunity in aged mice: an underlying lesion in IL 2 synthesis. J Immunol (1982) 1.33
CD4+ T cell activation and tolerance induction in B cell knockout mice. J Exp Med (1996) 1.32
Th1 and Th2 clones differ in their response to a tolerogenic signal. J Immunol (1990) 1.31
Specific suppression of the immune response by HGG tolerant spleen cells. I. Parameters affecting the level of suppression. J Immunol (1976) 1.30
Transfer of experimental autoimmune thyroiditis with T cell clones. J Immunol (1987) 1.28
Demonstration of a specific receptor for human C5a anaphylatoxin on murine macrophages. J Exp Med (1982) 1.28
High-affinity urokinase receptor antagonists identified with bacteriophage peptide display. Proc Natl Acad Sci U S A (1994) 1.26
Tolerogenicity of resting and activated B cells. J Exp Med (1994) 1.25
The immune response to human gamma-G-immunoglobulin in rabbits unresponsive to Fc fragment and H chain protein. J Immunol (1967) 1.25
The termination of immunological unresponsiveness to bovine serum albumin in rabbits. I. Quantitative and qualitative response to cross-reacting albumins. J Exp Med (1970) 1.24
In vivo induction of tolerance in murine CD4+ cell subsets. J Exp Med (1993) 1.22
T cell regulation of polyclonal B cell responsiveness. I. Helper effects of T cells. J Immunol (1979) 1.21
Immunologic unresponsiveness after gastric administration of human gamma-globulin: antigen requirements and cellular parameters. J Immunol (1980) 1.20
Fate of antigen-binding cells in unresponsive and immune mice. J Exp Med (1973) 1.20
Increased apolipoprotein E and c-fms gene expression without elevated interleukin 1 or 6 mRNA levels indicates selective activation of macrophage functions in advanced human atheroma. Proc Natl Acad Sci U S A (1992) 1.19
The effect of antigenic competition on antibody production to heterologous proteins, termination of immunologic unresponsiveness and induction of autoimmunity. J Immunol (1967) 1.17
The requirement for adherent cells in the Fc fragment-induced proliferative response of murine spleen cells. J Exp Med (1979) 1.15
Specific, transient suppression of the immune response by HGG tolerant spleen cells. II. Effector cells and target cells. J Immunol (1976) 1.14
The behavior of autologous thyroglobulin in the circulation of rabbits immunized with either heterologous or altered homologous thyroglobulin. J Immunol (1967) 1.13
The role of phagocytosis and natural lymphokines in the fusion of alveolar macrophages to form Langhans giant cells. J Reticuloendothel Soc (1975) 1.13
Immunologic responsiveness of the C3H/HeJ mouse: differential ability of butanol-extracted lipopolysaccharide (LPS) to evoke LPS-mediated effects. J Exp Med (1978) 1.13
Regulation of Fc fragment-induced murine spleen cell proliferation. J Exp Med (1980) 1.12
Studies on the catabolism of gamma- G subunits and chains. J Immunol (1965) 1.10
The induction of peripheral T cell unresponsiveness in adult mice by monomeric human gamma-globulin. J Immunol (1989) 1.09
Splenic role in the regulation of immune responses. Cell Immunol (1977) 1.09
2,4-Dinitrophenyl receptors on mouse thymus and spleen cells. J Exp Med (1973) 1.07
Possible roles of suppressor cells in immunologic tolerance. Transplant Rev (1975) 1.07
Th1 cell anergy and blockade in G1a phase of the cell cycle. J Immunol (1993) 1.07
Inability of the C3a anaphylatoxin to promote cellular lysis. Nature (1980) 1.07
Anti-bovine serum albumin specificity and binding affinity after termination of tolerance to bovine serum albumin. J Immunol (1965) 1.06
Role of C3 in the regulation of a splenic PFC response in rabbits. J Immunol (1980) 1.05
Passive transfer of experimental allergic encephalomyelitis by myelin basic protein-specific L3T4+ T cell clones possessing several functions. J Immunol (1986) 1.04
Polyclonal activation of murine B lymphocytes by Fc fragments. I. The requirement for two signals in the generation of the polyclonal antibody response induced by Fc fragments. J Immunol (1980) 1.04
Polyclonal B lymphocyte activation during Trypanosoma cruzi infection. J Immunol (1980) 1.03
The in vivo formation and fate of antigen-antibody complexes formed by fragments and polypeptide chains of rabbit gamma-G-antibodies. J Exp Med (1966) 1.03
The antibody response in rabbits to previously tolerated antigens. Ann N Y Acad Sci (1965) 1.03
In vivo behavior of homologous and heterologous thyroglobulin and induction of immunologic unresponsiveness to heterologous thyroglobulin. J Immunol (1967) 1.03
Regulation of the immune response. I. The potentiation of in vivo and in vitro immune responses by Fc fragments. J Exp Med (1980) 1.02
Effect of lipopolysaccharide on immunogenicity and tolerogenicity of HGG in C57BL/6J nude mice: evidence for a possible B cell deficiency. J Immunol (1977) 1.02
Anaphylatoxin-mediated regulation of the immune response. II. C5a-mediated enhancement of human humoral and T cell-mediated immune responses. J Immunol (1983) 1.02
Nonspecific activation of murine lymphocytes. IV. Proliferation of a distinct, late maturing lymphocyte subpopulation induced by 2-mercaptoethanol. J Immunol (1978) 1.02
Separation of various B-cell subpopulations from mouse spleen. I. Depletion of B cells by rosetting with glutaraldehyde-fixed, anti-immunoglobulin-coupled red blood cells. Cell Immunol (1979) 1.01
Fc fragment activation of T lymphocytes. I. Fc fragments trigger Lyt 1+23- T lymphocytes to release a helper T cell-replacing activity. J Immunol (1981) 1.01
Nonspecific activation of murine lymphocytes. V. Role of cellular collaboration between T and B lymphocytes in the proliferative and polyclonal response to 2-mercaptoethanol. J Immunol (1979) 1.01
Identification and characterization of the effector region within human C5a responsible for stimulation of IL-6 synthesis. J Immunol (1992) 1.01
Potentiation of the primary humoral immune response in vitro by C5a anaphylatoxin. J Immunol (1982) 1.01
Induction, maintenance and termination of immunologic unresponsiveness to bovine thyroglobulin in rabbits. J Immunol (1967) 1.01
Anaphylatoxin-mediated regulation of human and murine immune responses. Fed Proc (1984) 1.00
Antibody-producing cells in rabbits injected with soluble BSA. I. Hemolytic plaque assay. J Immunol (1968) 1.00