Published in Cell on August 26, 1994
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Loss of Rb activates both p53-dependent and independent cell death pathways in the developing mouse nervous system. EMBO J (1996) 2.63
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pRb inactivation in mammary cells reveals common mechanisms for tumor initiation and progression in divergent epithelia. PLoS Biol (2004) 1.27
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Astrocytes derived from p53-deficient mice provide a multistep in vitro model for development of malignant gliomas. Mol Cell Biol (1995) 1.20
Massive programmed cell death in intestinal epithelial cells induced by three-dimensional growth conditions: suppression by mutant c-H-ras oncogene expression. J Cell Biol (1995) 1.20
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Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53. Mol Cell Biol (1997) 1.17
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Decreased DNA repair but normal apoptosis in ultraviolet-irradiated skin of p53-transgenic mice. Am J Pathol (1996) 1.13
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The human papilloma virus 16E6 gene sensitizes human mammary epithelial cells to apoptosis induced by DNA damage. Proc Natl Acad Sci U S A (1995) 1.12
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Grape seed proanthocyanidins induce apoptosis through p53, Bax, and caspase 3 pathways. Neoplasia (2005) 1.08
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Full p53 transcriptional activation potential is dispensable for tumor suppression in diverse lineages. Proc Natl Acad Sci U S A (2011) 0.95
p53-regulated apoptosis is differentiation dependent in ultraviolet B-irradiated mouse keratinocytes. Am J Pathol (1998) 0.95
Potential role of p53 on metallothionein induction in human epithelial breast cancer cells. Br J Cancer (2002) 0.93
p53 negatively regulates intestinal immunity by delaying mucosal T cell cycling. J Clin Invest (2002) 0.93
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Illegitimate recombination leading to allelic loss and unbalanced translocation in p53-mutated human lymphoblastoid cells. Mol Cell Biol (1997) 0.90
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Susceptibility of p53-deficient mice to induction of mesothelioma by crocidolite asbestos fibers. Environ Health Perspect (1997) 0.88
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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice. Nature (2001) 10.56
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Radiation-induced cell cycle arrest compromised by p21 deficiency. Nature (1995) 8.53
Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53. Cell (1992) 7.06
p53 status and the efficacy of cancer therapy in vivo. Science (1994) 6.72
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p53-dependent apoptosis produced by Rb-deficiency in the developing mouse lens. Nature (1994) 4.52
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