Published in Development on November 01, 2001
BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development (2009) 2.21
RDH10 is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. Genes Dev (2007) 2.10
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Transgenic mice overexpressing BMP4 develop a fibrodysplasia ossificans progressiva (FOP)-like phenotype. Am J Pathol (2004) 1.60
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BMP-5 expression increases during chondrocyte differentiation in vivo and in vitro and promotes proliferation and cartilage matrix synthesis in primary chondrocyte cultures. J Cell Physiol (2008) 0.95
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BMP-2 functions independently of SHH signaling and triggers cell condensation and apoptosis in regenerating axolotl limbs. BMC Dev Biol (2010) 0.93
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A clinically relevant model of osteoinduction: a process requiring calcium phosphate and BMP/Wnt signalling. J Cell Mol Med (2009) 0.91
Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation. Mol Cell Biol (2003) 0.91
SHP2 regulates chondrocyte terminal differentiation, growth plate architecture and skeletal cell fates. PLoS Genet (2014) 0.90
Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/B23 during chondrocyte differentiation. Mol Cell Biol (2008) 0.89
BMPRIA mediated signaling is essential for temporomandibular joint development in mice. PLoS One (2014) 0.88
Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One (2012) 0.88
TGF-β and BMP signaling in osteoblast, skeletal development, and bone formation, homeostasis and disease. Bone Res (2016) 0.88
GREM1, FRZB and DKK1 mRNA levels correlate with osteoarthritis and are regulated by osteoarthritis-associated factors. Arthritis Res Ther (2013) 0.87
Aggrecan is required for growth plate cytoarchitecture and differentiation. Dev Biol (2014) 0.87
Coordination of chondrogenesis and osteogenesis by hypertrophic chondrocytes in endochondral bone development. J Bone Miner Metab (2010) 0.86
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Enthesis fibrocartilage cells originate from a population of Hedgehog-responsive cells modulated by the loading environment. Development (2015) 0.84
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Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation. Biochem J (2012) 0.83
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Fetal mesenchymal stromal cells differentiating towards chondrocytes acquire a gene expression profile resembling human growth plate cartilage. PLoS One (2012) 0.82
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Suppressor of fused (Sufu) mediates the effect of parathyroid hormone-like hormone (Pthlh) on chondrocyte differentiation in the growth plate. J Biol Chem (2012) 0.82
Matrilin-3 inhibits chondrocyte hypertrophy as a bone morphogenetic protein-2 antagonist. J Biol Chem (2014) 0.82
Developmental cues for bone formation from parathyroid hormone and parathyroid hormone-related protein in an ex vivo organotypic culture system of embryonic chick femora. Tissue Eng Part C Methods (2012) 0.82
Bone morphogenetic protein signaling in musculoskeletal cancer. J Cancer Res Clin Oncol (2016) 0.82
Indian hedgehog signaling regulates transcription and expression of collagen type X via Runx2/Smads interactions. J Biol Chem (2014) 0.81
Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol (2013) 0.81
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CCAAT/enhancer binding protein β regulates expression of Indian hedgehog during chondrocytes differentiation. PLoS One (2014) 0.79
Skeletal plasticity in response to embryonic muscular activity underlies the development and evolution of the perching digit of birds. Sci Rep (2015) 0.78
Regulation of α5 and αV Integrin Expression by GDF-5 and BMP-7 in Chondrocyte Differentiation and Osteoarthritis. PLoS One (2015) 0.78
Multiple tissue-specific requirements for the BMP antagonist Noggin in development of the mammalian craniofacial skeleton. Dev Biol (2014) 0.78
Periosteal PTHrP Regulates Cortical Bone Remodeling During Fracture Healing. Bone (2015) 0.78
Expression of BMP and Actin Membrane Bound Inhibitor Is Increased during Terminal Differentiation of MSCs. Stem Cells Int (2016) 0.77
Mesenchymal stem cells overexpressing Ihh promote bone repair. J Orthop Surg Res (2014) 0.77
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Disp1 regulates growth of mammalian long bones through the control of Ihh distribution. Dev Biol (2008) 0.77
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Molecular study of a Hoxa2 gain-of-function in chondrogenesis: a model of idiopathic proportionate short stature. Int J Mol Sci (2013) 0.77
BMP regulates regional gene expression in the dorsal otocyst through canonical and non-canonical intracellular pathways. Development (2016) 0.77
The inhibitory effect of salmon calcitonin on tri-iodothyronine induction of early hypertrophy in articular cartilage. PLoS One (2012) 0.76
Dynamic mRNA and miRNA expression analysis in response to intermuscular bone development of blunt snout bream (Megalobrama amblycephala). Sci Rep (2016) 0.76
PTHrP treatment fails to rescue bone defects caused by Hedgehog pathway inhibition in young mice. Toxicol Pathol (2011) 0.76
Osteochondromas in fibrodysplasia ossificans progressiva: a widespread trait with a streaking but overlooked appearance when arising at femoral bone end. Rheumatol Int (2015) 0.75
Water temperature induces jaw deformity and bone morphogenetic proteins (BMPs) gene expression in golden pompano Trachinotus ovatus larvae. Springerplus (2016) 0.75
Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation. Sci Rep (2016) 0.75
Electrical stimulation drives chondrogenesis of mesenchymal stem cells in the absence of exogenous growth factors. Sci Rep (2016) 0.75
Gremlin-1 Concentrations Are Correlated with the Severity of Knee Osteoarthritis. Med Sci Monit (2016) 0.75
Endochondral Ossification Is Accelerated in Cholinesterase-Deficient Mice and in Avian Mesenchymal Micromass Cultures. PLoS One (2017) 0.75
Pathogenesis and treatment of spine disease in the mucopolysaccharidoses. Mol Genet Metab (2016) 0.75
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