Published in Proc Natl Acad Sci U S A on April 26, 1994
Structure and function in rhodopsin: high-level expression of rhodopsin with restricted and homogeneous N-glycosylation by a tetracycline-inducible N-acetylglucosaminyltransferase I-negative HEK293S stable mammalian cell line. Proc Natl Acad Sci U S A (2002) 5.91
Crystal structure of a thermally stable rhodopsin mutant. J Mol Biol (2007) 2.80
Structure and function in rhodopsin: a tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants. Proc Natl Acad Sci U S A (2002) 2.48
G protein-coupled receptor rhodopsin: a prospectus. Annu Rev Physiol (2002) 2.08
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. Proc Natl Acad Sci U S A (1994) 1.62
Identification of core amino acids stabilizing rhodopsin. Proc Natl Acad Sci U S A (2004) 1.48
Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket. Proc Natl Acad Sci U S A (1999) 1.46
Functional analysis of a mammalian odorant receptor subfamily. J Neurochem (2006) 1.30
Structure and function in rhodopsin: packing of the helices in the transmembrane domain and folding to a tertiary structure in the intradiscal domain are coupled. Proc Natl Acad Sci U S A (1997) 1.29
Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. Proc Natl Acad Sci U S A (1997) 1.25
Structure and function in rhodopsin: correct folding and misfolding in point mutants at and in proximity to the site of the retinitis pigmentosa mutation Leu-125-->Arg in the transmembrane helix C. Proc Natl Acad Sci U S A (1996) 1.22
A naturally occurring mutation of the opsin gene (T4R) in dogs affects glycosylation and stability of the G protein-coupled receptor. J Biol Chem (2004) 1.19
In vivo assembly of rhodopsin from expressed polypeptide fragments. Proc Natl Acad Sci U S A (1995) 1.18
Large-scale production and study of a synthetic G protein-coupled receptor: human olfactory receptor 17-4. Proc Natl Acad Sci U S A (2009) 1.16
Study of a synthetic human olfactory receptor 17-4: expression and purification from an inducible mammalian cell line. PLoS One (2008) 1.11
Misfolded proteins and retinal dystrophies. Adv Exp Med Biol (2010) 1.09
N-glycosylation requirements for the AT1a angiotensin II receptor delivery to the plasma membrane. Biochem J (1999) 1.08
Expression, stability, and membrane integration of truncation mutants of bovine rhodopsin. Proc Natl Acad Sci U S A (1997) 1.04
Molecular chaperones and photoreceptor function. Prog Retin Eye Res (2008) 1.04
Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function. Proc Natl Acad Sci U S A (1999) 1.04
Structure and activation of rhodopsin. Acta Pharmacol Sin (2012) 1.04
Gene therapy in animal models of autosomal dominant retinitis pigmentosa. Mol Vis (2012) 0.99
Calnexin is not essential for mammalian rod opsin biogenesis. Mol Vis (2008) 0.97
Ice breaking in GPCR structural biology. Acta Pharmacol Sin (2012) 0.97
Protein misfolding and retinal degeneration. Cold Spring Harb Perspect Biol (2011) 0.96
N-glycan-mediated quality control in the endoplasmic reticulum is required for the expression of correctly folded delta-opioid receptors at the cell surface. J Biol Chem (2008) 0.93
Tuning microbial hosts for membrane protein production. Microb Cell Fact (2009) 0.91
Rhodopsin: the functional significance of asn-linked glycosylation and other post-translational modifications. Ophthalmic Genet (2009) 0.90
BiP prevents rod opsin aggregation. Mol Biol Cell (2012) 0.89
Palmitylation of cone opsins. Vision Res (2006) 0.89
Heterologous expression of functional G-protein-coupled receptors in Caenorhabditis elegans. FASEB J (2011) 0.89
Isolation and characterization of melanopsin (Opn4) from the Australian marsupial Sminthopsis crassicaudata (fat-tailed dunnart). Proc Biol Sci (2007) 0.86
Endoplasmic reticulum-associated degradation of a degron-containing polytopic membrane protein. Mol Membr Biol (2009) 0.86
Inherent instability of the retinitis pigmentosa P23H mutant opsin. J Biol Chem (2014) 0.85
Requirement of N-glycosylation of the prostaglandin E2 receptor EP3beta for correct sorting to the plasma membrane but not for correct folding. Biochem J (2000) 0.85
Exposure at the cell surface is required for gas3/PMP22 To regulate both cell death and cell spreading: implication for the Charcot-Marie-Tooth type 1A and Dejerine-Sottas diseases. Mol Biol Cell (2000) 0.84
Identification of the glycosylation sites utilized on the V1a vasopressin receptor and assessment of their role in receptor signalling and expression. Biochem J (2001) 0.84
Naturally-occurring mutation in the calcium-sensing receptor reveals the significance of extracellular domain loop III region for class C G-protein-coupled receptor function. J Clin Endocrinol Metab (2010) 0.83
Production of a bioengineered G-protein coupled receptor of human formyl peptide receptor 3. PLoS One (2011) 0.82
Alternative Splicing of G Protein-Coupled Receptors: Relevance to Pain Management. Mayo Clin Proc (2015) 0.81
Early structural anomalies observed by high-resolution imaging in two related cases of autosomal-dominant retinitis pigmentosa. Ophthalmic Surg Lasers Imaging Retina (2015) 0.78
NLRP3 inflammasome activation drives bystander cone photoreceptor cell death in a P23H rhodopsin model of retinal degeneration. Hum Mol Genet (2016) 0.78
Comparison of dynamics of extracellular accesses to the β(1) and β(2) adrenoceptors binding sites uncovers the potential of kinetic basis of antagonist selectivity. Chem Biol Drug Des (2012) 0.78
Point mutations in bovine opsin can be classified in four groups with respect to their effect on the biosynthetic pathway of opsin. Biochem J (1996) 0.78
The G protein-coupled receptor rhodopsin: a historical perspective. Methods Mol Biol (2015) 0.78
Interacting targets of the farnesyl of transducin gamma-subunit. Biochemistry (2008) 0.78
Characterization of adenosine receptor in its native environment: insights from molecular dynamics simulations of palmitoylated/glycosylated, membrane-integrated human A(2B) adenosine receptor. J Mol Model (2012) 0.77
Asn54-linked glycan is critical for functional folding of intercellular adhesion molecule-5. Glycoconj J (2011) 0.75
Structure and function of the N-linked glycans of HBP/CAP37/azurocidin: crystal structure determination and biological characterization of nonglycosylated HBP. Protein Sci (1999) 0.75
Functional role of positively selected amino acid substitutions in mammalian rhodopsin evolution. Sci Rep (2016) 0.75
Dim-light photoreceptor of chub mackerel Scomber japonicus and the photoresponse upon illumination with LEDs of different wavelengths. Fish Physiol Biochem (2016) 0.75
Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (1970) 1528.65
DNA sequencing with chain-terminating inhibitors. Proc Natl Acad Sci U S A (1977) 790.54
"Western blotting": electrophoretic transfer of proteins from sodium dodecyl sulfate--polyacrylamide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal Biochem (1981) 71.15
Assembly of asparagine-linked oligosaccharides. Annu Rev Biochem (1985) 26.05
Biological roles of oligosaccharides: all of the theories are correct. Glycobiology (1993) 12.38
Synthesis and processing of asparagine-linked oligosaccharides. Annu Rev Biochem (1981) 11.44
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proc Natl Acad Sci U S A (1987) 5.11
Flow of information in the light-triggered cyclic nucleotide cascade of vision. Proc Natl Acad Sci U S A (1981) 4.87
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proc Natl Acad Sci U S A (1989) 4.44
Rhodopsin mutations in autosomal dominant retinitis pigmentosa. Proc Natl Acad Sci U S A (1991) 4.10
Functional heterogeneity of mutant rhodopsins responsible for autosomal dominant retinitis pigmentosa. Proc Natl Acad Sci U S A (1991) 3.19
Total synthesis of a gene for bovine rhodopsin. Proc Natl Acad Sci U S A (1986) 3.08
A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. J Biol Chem (1988) 2.37
Rhodopsin, photoreceptor of the rod cell. An emerging pattern for structure and function. J Biol Chem (1992) 2.24
Role of the intradiscal domain in rhodopsin assembly and function. Proc Natl Acad Sci U S A (1990) 1.97
Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin. J Biol Chem (1992) 1.82
Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin. J Biol Chem (1991) 1.80
Identification of novel rhodopsin mutations associated with retinitis pigmentosa by GC-clamped denaturing gradient gel electrophoresis. Am J Hum Genet (1991) 1.62
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. Proc Natl Acad Sci U S A (1994) 1.62
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. Biochemistry (1993) 1.55
Allosteric behavior in transducin activation mediated by rhodopsin. Initial rate analysis of guanine nucleotide exchange. J Biol Chem (1987) 1.52
Mutational analysis of beta-adrenergic receptor glycosylation. J Biol Chem (1990) 1.51
Rhodopsin carbohydrate. Structure of small oligosaccharides attached at two sites near the NH2 terminus. J Biol Chem (1979) 1.49
The resistance to flexion of the lumbar intervertebral joint. Spine (Phila Pa 1976) (1980) 1.48
Palmitoylation of bovine opsin and its cysteine mutants in COS cells. Proc Natl Acad Sci U S A (1993) 1.41
Absorption spectrum of rhodopsin denatured with acid. Nature (1968) 1.41
Expression of a bovine rhodopsin gene in Xenopus oocytes: demonstration of light-dependent ionic currents. Proc Natl Acad Sci U S A (1988) 1.20
Molecular analysis and genetic mapping of the rhodopsin gene in families with autosomal dominant retinitis pigmentosa. Genomics (1993) 1.01
Light-stable rhodopsin. I. A rhodopsin analog reconstituted with a nonisomerizable 11-cis retinal derivative. J Biol Chem (1992) 1.01
Tunicamycin blocks the incorporation of opsin into retinal rod outer segment membranes. Proc Natl Acad Sci U S A (1985) 0.97
Role of glycosylation for beta 2-adrenoceptor function in A431 cells. J Biol Chem (1988) 0.94
Disruption of potential sites for N-linked glycosylation does not impair hormone binding to the lutropin/choriogonadotropin receptor if Asn-173 is left intact. J Biol Chem (1993) 0.89
Functional expression in vitro of bovine visual rhodopsin. Protein Eng (1990) 0.88
Molecular genetics of inherited retinal degenerations. Curr Opin Genet Dev (1992) 0.84
In vitro expression of bovine opsin using recombinant baculovirus: the role of glutamic acid (134) in opsin biosynthesis and glycosylation. Biochim Biophys Acta (1991) 0.84
CV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxyribonucleotide corresponding to the nucleotide sequence 31 to 50. J Mol Biol (1972) 58.52
Reversal of bacteriophage T4 induced polynucleotide kinase action. Biochemistry (1973) 21.41
Physical characterization and simultaneous purification of bacteriophage T4 induced polynucleotide kinase, polynucleotide ligase, and deoxyribonucleic acid polymerase. Biochemistry (1973) 11.45
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science (1996) 6.50
High-pressure liquid chromatography in polynucleotide synthesis. Biochemistry (1978) 5.98
Expression of a synthetic bovine rhodopsin gene in monkey kidney cells. Proc Natl Acad Sci U S A (1987) 5.11
Vibrational spectroscopy of bacteriorhodopsin mutants: light-driven proton transport involves protonation changes of aspartic acid residues 85, 96, and 212. Biochemistry (1988) 4.93
Glutamic acid-113 serves as the retinylidene Schiff base counterion in bovine rhodopsin. Proc Natl Acad Sci U S A (1989) 4.44
A collision gradient method to determine the immersion depth of nitroxides in lipid bilayers: application to spin-labeled mutants of bacteriorhodopsin. Proc Natl Acad Sci U S A (1994) 4.27
Transmembrane protein structure: spin labeling of bacteriorhodopsin mutants. Science (1990) 4.07
Studies on polynucleotides. LI. Syntheses of the 64 possible ribotrinucleotides derived from the four major ribomononucleotides. J Am Chem Soc (1966) 3.83
Amino acid sequence of bacteriorhodopsin. Proc Natl Acad Sci U S A (1979) 3.74
Studies on polynucleotides, XLIX. Stimulation of the binding of aminoacyl-sRNA's to ribosomes by ribotrinucleotides and a survey of codon assignments for 20 amino acids. Proc Natl Acad Sci U S A (1965) 3.71
Specific amino acid substitutions in bacterioopsin: Replacement of a restriction fragment in the structural gene by synthetic DNA fragments containing altered codons. Proc Natl Acad Sci U S A (1984) 3.67
The bacteriorhodopsin gene. Proc Natl Acad Sci U S A (1981) 3.40
Structural studies on transmembrane proteins. 2. Spin labeling of bacteriorhodopsin mutants at unique cysteines. Biochemistry (1989) 3.25
Aspartic acid substitutions affect proton translocation by bacteriorhodopsin. Proc Natl Acad Sci U S A (1988) 3.13
Studies on polynucleotides, C. A novel joining reaction catalyzed by the T4-polynucleotide ligase. Proc Natl Acad Sci U S A (1970) 3.11
Total synthesis of a gene for bovine rhodopsin. Proc Natl Acad Sci U S A (1986) 3.08
Aspartic acid-96 is the internal proton donor in the reprotonation of the Schiff base of bacteriorhodopsin. Proc Natl Acad Sci U S A (1989) 3.06
Cysteine residues 110 and 187 are essential for the formation of correct structure in bovine rhodopsin. Proc Natl Acad Sci U S A (1988) 3.01
Structure and function in rhodopsin. 7. Point mutations associated with autosomal dominant retinitis pigmentosa. Biochemistry (1994) 2.88
Substitution of amino acids Asp-85, Asp-212, and Arg-82 in bacteriorhodopsin affects the proton release phase of the pump and the pK of the Schiff base. Proc Natl Acad Sci U S A (1990) 2.80
Bacterio-opsin mRNA in wild-type and bacterio-opsin-deficient Halobacterium halobium strains. Proc Natl Acad Sci U S A (1984) 2.77
A transposable element from Halobacterium halobium which inactivates the bacteriorhodopsin gene. Proc Natl Acad Sci U S A (1982) 2.76
High-frequency spontaneous mutation in the bacterio-opsin gene in Halobacterium halobium is mediated by transposable elements. Proc Natl Acad Sci U S A (1983) 2.70
Replacement of aspartic acid-96 by asparagine in bacteriorhodopsin slows both the decay of the M intermediate and the associated proton movement. Proc Natl Acad Sci U S A (1989) 2.64
Total synthesis of the gene for an alanine transfer ribonucleic acid from yeast. Nature (1970) 2.51
Studies on polynucleotides, lxviii the primary structure of yeast phenylalanine transfer RNA. Proc Natl Acad Sci U S A (1967) 2.45
Total synthesis of a gene. Science (1979) 2.38
A single amino acid substitution in rhodopsin (lysine 248----leucine) prevents activation of transducin. J Biol Chem (1988) 2.37
CIV. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. Chemical synthesis of an icosadeoxynucleotide corresponding to the nucleotide sequence 21 to 40. J Mol Biol (1972) 2.35
Structure and function in rhodopsin. Measurement of the rate of metarhodopsin II decay by fluorescence spectroscopy. J Biol Chem (1995) 2.34
Structure and function in rhodopsin: high level expression of a synthetic bovine opsin gene and its mutants in stable mammalian cell lines. Proc Natl Acad Sci U S A (1996) 2.24
Orientation of bacteriorhodopsin in Halobacterium halobium as studied by selective proteolysis. Proc Natl Acad Sci U S A (1977) 2.23
Assembly of functional rhodopsin requires a disulfide bond between cysteine residues 110 and 187. J Biol Chem (1990) 2.18
The nucleotide sequence in the promoter region of the fene for an Escherichia coli tyrosine transfer ribonucleic acid. J Biol Chem (1975) 2.17
Partial primary structure of bacteriorhodopsin: sequencing methods for membrane proteins. Proc Natl Acad Sci U S A (1979) 2.17
Rhodopsin mutants that bind but fail to activate transducin. Science (1990) 2.16
GTPase of bovine rod outer segments: the amino acid sequence of the alpha subunit as derived from the cDNA sequence. Proc Natl Acad Sci U S A (1985) 2.09
Studies on polynucleotides. 118. A further study of ribonucleotide incorporation into deoxyribonucleic acid chains by deoxyribonucleic acid polymerase I of Escherichia coli. J Biol Chem (1972) 2.09
Glycerophospholipid synthesis: improved general method and new analogs containing photoactivable groups. Proc Natl Acad Sci U S A (1977) 2.07
Studies on polynucleotides. LXIX. Synthetic deoxyribopolynucleotides as templates for the DNA polymerase of Escherichia coli: DNA-like polymers containing repeating trinucleotide sequences. J Mol Biol (1967) 2.06
Replacement of aspartic residues 85, 96, 115, or 212 affects the quantum yield and kinetics of proton release and uptake by bacteriorhodopsin. Proc Natl Acad Sci U S A (1989) 2.04
Refolding of an integral membrane protein. Denaturation, renaturation, and reconstitution of intact bacteriorhodopsin and two proteolytic fragments. J Biol Chem (1981) 2.03
Studies on polynucleotides. LXVII. Initiation of protein synthesis in vitro as studied by using ribopolynucleotides with repeating nucleotide sequences as messengers. J Mol Biol (1967) 2.02
Nucleotide sequence in the promoter region of the Escherichia coli tyrosine tRNA gene. Proc Natl Acad Sci U S A (1974) 2.01
Role of the intradiscal domain in rhodopsin assembly and function. Proc Natl Acad Sci U S A (1990) 1.97
Protonation state of Asp (Glu)-85 regulates the purple-to-blue transition in bacteriorhodopsin mutants Arg-82----Ala and Asp-85----Glu: the blue form is inactive in proton translocation. Proc Natl Acad Sci U S A (1990) 1.94
Total synthesis of the structural gene for the precursor of a tyrosine suppressor transfer RNA from Escherichia coli. 1. General introduction. J Biol Chem (1976) 1.91
Studies on polynucleotides. 103. Total synthesis of the structural gene for an alanine transfer ribonucleic acid from yeast. J Mol Biol (1972) 1.90
Structural features and light-dependent changes in the cytoplasmic interhelical E-F loop region of rhodopsin: a site-directed spin-labeling study. Biochemistry (1996) 1.88
Studies on polynucleotides. XCVI. Repair replications of short synthetic DNA's as catalyzed by DNA polymerases. J Mol Biol (1971) 1.87
Site of attachment of retinal in bacteriorhodopsin. Proc Natl Acad Sci U S A (1981) 1.87
Structure of the lipopolysaccharide from an Escherichia coli heptose-less mutant. I. Chemical degradations and identification of products. J Biol Chem (1979) 1.86
Structure and function in rhodopsin. Studies of the interaction between the rhodopsin cytoplasmic domain and transducin. J Biol Chem (1992) 1.82
Mapping of the amino acids in membrane-embedded helices that interact with the retinal chromophore in bovine rhodopsin. J Biol Chem (1991) 1.80
Rapid long-range proton diffusion along the surface of the purple membrane and delayed proton transfer into the bulk. Proc Natl Acad Sci U S A (1995) 1.77
Structure-function studies on bacteriorhodopsin. X. Individual substitutions of arginine residues by glutamine affect chromophore formation, photocycle, and proton translocation. J Biol Chem (1989) 1.73
Studies on polynucleotides. LXXXVII. The joining of short deoxyribopolynucleotides by DNA-joining enzymes. Proc Natl Acad Sci U S A (1968) 1.72
Polynucleotide ligase-catalyzed joining of deoxyribo-oligonucleotides on ribopolynucleotide templates and of ribo-oligonucleotides on deoxyribopolynucleotide templates. Proc Natl Acad Sci U S A (1970) 1.70
Time-resolved detection of structural changes during the photocycle of spin-labeled bacteriorhodopsin. Science (1994) 1.70
Replacement of leucine-93 by alanine or threonine slows down the decay of the N and O intermediates in the photocycle of bacteriorhodopsin: implications for proton uptake and 13-cis-retinal----all-trans-retinal reisomerization. Proc Natl Acad Sci U S A (1991) 1.69
Site-directed isotope labelling and FTIR spectroscopy of bacteriorhodopsin. Nat Struct Biol (1994) 1.67
A further study of misreading of codons induced by streptomycin and neomycin using ribopolynucleotides containing two nucleotides in alternating sequence as templates. J Mol Biol (1966) 1.65
Vibrational spectroscopy of bacteriorhodopsin mutants: I. Tyrosine-185 protonates and deprotonates during the photocycle. Proteins (1988) 1.63
Chemical synthesis and cloning of a tyrosine tRNA gene. Methods Enzymol (1979) 1.63
Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. Proc Natl Acad Sci U S A (1994) 1.62
Structure-function studies on bacteriorhodopsin. III. Total synthesis of a gene for bacterio-opsin and its expression in Escherichia coli. J Biol Chem (1987) 1.62
Nucleotide sequence studies on yeast phenylalanine sRNA. Cold Spring Harb Symp Quant Biol (1966) 1.61
Structure and function in rhodopsin: correct folding and misfolding in two point mutants in the intradiscal domain of rhodopsin identified in retinitis pigmentosa. Proc Natl Acad Sci U S A (1996) 1.61
Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent. Proc Natl Acad Sci U S A (2001) 1.61
Denaturation and renaturation of bacteriorhodopsin in detergents and lipid-detergent mixtures. J Biol Chem (1982) 1.60
Bacteriorhodopsin mutants containing single tyrosine to phenylalanine substitutions are all active in proton translocation. Proc Natl Acad Sci U S A (1987) 1.58
Studies on polynucleotides. CXVII. Hybridization of polydeoxynucleotides with tyrosine transfer RNA sequences to the r-strand of phi80psu + 3 DNA. J Mol Biol (1972) 1.58
Studies on polynucleotides, 88. Enzymatic joining of chemically synthesized segments corresponding to the gene for alanine-tRNA. Proc Natl Acad Sci U S A (1968) 1.57
Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. Biochemistry (1993) 1.55
Mechanism of light-dependent proton translocation by bacteriorhodopsin. J Bacteriol (1993) 1.52
Structure-function studies on bacteriorhodopsin. V. Effects of amino acid substitutions in the putative helix F. J Biol Chem (1987) 1.51
Bacteriorhodopsin: partial sequence of mRNA provides amino acid sequence in the precursor region. Proc Natl Acad Sci U S A (1981) 1.48
Studies on polynucleotides. CXXII. The dodecanucleotide sequence adjoining the C-C-A end of the tyrosine transfer ribonucleic acid gene. J Biol Chem (1973) 1.48
Structure and function in rhodopsin: kinetic studies of retinal binding to purified opsin mutants in defined phospholipid-detergent mixtures serve as probes of the retinal binding pocket. Proc Natl Acad Sci U S A (1999) 1.46
NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. Proc Natl Acad Sci U S A (1999) 1.43
Delipidation of bacteriorhodopsin and reconstitution with exogenous phospholipid. Proc Natl Acad Sci U S A (1980) 1.43
Orientation of retinal in bacteriorhodopsin as studied by cross-linking using a photosensitive analog of retinal. J Biol Chem (1982) 1.43
The retinylidene Schiff base counterion in bacteriorhodopsin. J Biol Chem (1991) 1.42
Bacteriorhodopsin mutants containing single substitutions of serine or threonine residues are all active in proton translocation. J Biol Chem (1991) 1.41
Studies on polynucleotides. CII. The use of aromatic isocyanates for selective blocking of the terminal 3'-hydroxyl group in protected deoxyribooligonucleotides. J Am Chem Soc (1972) 1.41
Palmitoylation of bovine opsin and its cysteine mutants in COS cells. Proc Natl Acad Sci U S A (1993) 1.41
Structure-function studies on bacteriorhodopsin. IX. Substitutions of tryptophan residues affect protein-retinal interactions in bacteriorhodopsin. J Biol Chem (1989) 1.40
Studies on polynucleotides. LXXIV. Direct translation in vitro of single-stranded DNA-like polymers with repeating nucleotide sequences in the presence of neomycin B. J Mol Biol (1967) 1.38
The role of the retinylidene Schiff base counterion in rhodopsin in determining wavelength absorbance and Schiff base pKa. Proc Natl Acad Sci U S A (1991) 1.38
Expression of the bacterioopsin gene in Halobacterium halobium using a multicopy plasmid. Proc Natl Acad Sci U S A (1991) 1.37
Mapping light-dependent structural changes in the cytoplasmic loop connecting helices C and D in rhodopsin: a site-directed spin labeling study. Biochemistry (1995) 1.37
Chemical synthesis of polynucleotides. Angew Chem Int Ed Engl (1972) 1.36