Published in Genes Dev on October 16, 2012
lincRNAs: genomics, evolution, and mechanisms. Cell (2013) 6.50
Long noncoding RNAs: cellular address codes in development and disease. Cell (2013) 6.01
Detecting and characterizing circular RNAs. Nat Biotechnol (2014) 2.73
Ribosome profiling reveals pervasive translation outside of annotated protein-coding genes. Cell Rep (2014) 2.04
Multiplexed and programmable regulation of gene networks with an integrated RNA and CRISPR/Cas toolkit in human cells. Mol Cell (2014) 2.02
Posttranscriptional gene regulation by long noncoding RNA. J Mol Biol (2012) 1.87
Unique features of long non-coding RNA biogenesis and function. Nat Rev Genet (2015) 1.81
Evolutionary conservation of long non-coding RNAs; sequence, structure, function. Biochim Biophys Acta (2013) 1.79
Extensive localization of long noncoding RNAs to the cytosol and mono- and polyribosomal complexes. Genome Biol (2014) 1.66
Short intronic repeat sequences facilitate circular RNA production. Genes Dev (2014) 1.61
Molecular biology. A circuitous route to noncoding RNA. Science (2013) 1.47
A conserved virus-induced cytoplasmic TRAMP-like complex recruits the exosome to target viral RNA for degradation. Genes Dev (2016) 1.40
Selective Preference of Parallel DNA Triplexes Is Due to the Disruption of Hoogsteen Hydrogen Bonds Caused by the Severe Nonisostericity between the G*GC and T*AT Triplets. PLoS One (2016) 1.39
A 3' Poly(A) Tract Is Required for LINE-1 Retrotransposition. Mol Cell (2015) 1.23
Paraspeckle formation during the biogenesis of long non-coding RNAs. RNA Biol (2013) 1.22
microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus. Sci Rep (2013) 1.18
Widespread purifying selection on RNA structure in mammals. Nucleic Acids Res (2013) 1.18
Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix. Nat Struct Mol Biol (2014) 1.18
Circular RNAs in cancer: novel insights into origins, properties, functions and implications. Am J Cancer Res (2015) 1.13
LncRNA MALAT1 functions as a competing endogenous RNA to regulate ZEB2 expression by sponging miR-200s in clear cell kidney carcinoma. Oncotarget (2015) 1.12
p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med (2016) 1.10
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability. Biochim Biophys Acta (2015) 1.08
Pyrimidine motif triple helix in the Kluyveromyces lactis telomerase RNA pseudoknot is essential for function in vivo. Proc Natl Acad Sci U S A (2013) 1.08
Structural basis for the Nanos-mediated recruitment of the CCR4-NOT complex and translational repression. Genes Dev (2014) 1.04
Noncoding RNA in oncogenesis: a new era of identifying key players. Int J Mol Sci (2013) 1.03
The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay. PLoS Genet (2013) 1.01
Viral noncoding RNAs: more surprises. Genes Dev (2015) 0.99
Deep sequencing shows multiple oligouridylations are required for 3' to 5' degradation of histone mRNAs on polyribosomes. Mol Cell (2014) 0.99
Combinatorial control of Drosophila circular RNA expression by intronic repeats, hnRNPs, and SR proteins. Genes Dev (2015) 0.99
Nonsense-Mediated mRNA Decay: Degradation of Defective Transcripts Is Only Part of the Story. Annu Rev Genet (2015) 0.98
Non-coding RNA: a new frontier in regulatory biology. Natl Sci Rev (2014) 0.95
LncRNA MALAT1 enhances oncogenic activities of EZH2 in castration-resistant prostate cancer. Oncotarget (2015) 0.93
The emerging role of triple helices in RNA biology. Wiley Interdiscip Rev RNA (2013) 0.93
miRISC and the CCR4-NOT complex silence mRNA targets independently of 43S ribosomal scanning. EMBO J (2016) 0.92
Long non-coding RNAs in cancer and development: where do we go from here? Int J Mol Sci (2015) 0.92
Elements and machinery of non-coding RNAs: toward their taxonomy. EMBO Rep (2014) 0.88
Long noncoding RNAs in diseases of aging. Biochim Biophys Acta (2015) 0.88
On-enzyme refolding permits small RNA and tRNA surveillance by the CCA-adding enzyme. Cell (2015) 0.88
The many faces of long noncoding RNAs. FEBS J (2014) 0.87
Long noncoding RNA turnover. Biochimie (2015) 0.84
Non-mRNA 3' end formation: how the other half lives. Wiley Interdiscip Rev RNA (2013) 0.84
Evolution to the rescue: using comparative genomics to understand long non-coding RNAs. Nat Rev Genet (2016) 0.83
Controlling translation via modulation of tRNA levels. Wiley Interdiscip Rev RNA (2015) 0.83
Long and short non-coding RNAs as regulators of hematopoietic differentiation. Int J Mol Sci (2013) 0.83
Major satellite repeat RNA stabilize heterochromatin retention of Suv39h enzymes by RNA-nucleosome association and RNA:DNA hybrid formation. Elife (2017) 0.83
Discovery and Classification of Fusion Transcripts in Prostate Cancer and Normal Prostate Tissue. Am J Pathol (2015) 0.83
Non-coding RNAs in muscle dystrophies. Int J Mol Sci (2013) 0.82
Cytoplasmic long noncoding RNAs are frequently bound to and degraded at ribosomes in human cells. RNA (2016) 0.82
Panning for Long Noncoding RNAs. Biomolecules (2013) 0.81
DIS3 shapes the RNA polymerase II transcriptome in humans by degrading a variety of unwanted transcripts. Genome Res (2015) 0.81
Determinants and implications of mRNA poly(A) tail size--does this protein make my tail look big? Semin Cell Dev Biol (2014) 0.80
RNA cleavage products generated by antisense oligonucleotides and siRNAs are processed by the RNA surveillance machinery. Nucleic Acids Res (2016) 0.80
Functions and mechanisms of long noncoding RNAs in lung cancer. Onco Targets Ther (2016) 0.79
High-Resolution Mapping of RNA-Binding Regions in the Nuclear Proteome of Embryonic Stem Cells. Mol Cell (2016) 0.79
New insights into the expression and functions of the Kaposi's sarcoma-associated herpesvirus long noncoding PAN RNA. Virus Res (2015) 0.78
Novel 3' ends that support translation. Genes Dev (2012) 0.78
Myriad Triple-Helix-Forming Structures in the Transposable Element RNAs of Plants and Fungi. Cell Rep (2016) 0.78
Long non-coding RNAs in corticogenesis: deciphering the non-coding code of the brain. EMBO J (2015) 0.78
Long noncoding RNAs in viral infections. Virus Res (2015) 0.78
CCAR1 5' UTR as a natural miRancer of miR-1254 overrides tamoxifen resistance. Cell Res (2016) 0.77
Viral Evasion and Manipulation of Host RNA Quality Control Pathways. J Virol (2016) 0.77
Hoogsteen-position pyrimidines promote the stability and function of the MALAT1 RNA triple helix. RNA (2016) 0.77
Structure Prediction: New Insights into Decrypting Long Noncoding RNAs. Int J Mol Sci (2016) 0.77
Chromatin remodeling complexes in the assembly of long noncoding RNA-dependent nuclear bodies. Nucleus (2015) 0.77
Oligoadenylation of 3' decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells. RNA (2016) 0.77
Paraspeckles modulate the intranuclear distribution of paraspeckle-associated Ctn RNA. Sci Rep (2016) 0.77
Controlling mRNA stability and translation with the CRISPR endoribonuclease Csy4. RNA (2015) 0.77
New Perspectives on DNA and RNA Triplexes As Effectors of Biological Activity. PLoS Genet (2015) 0.77
Widespread Influence of 3'-End Structures on Mammalian mRNA Processing and Stability. Cell (2017) 0.76
Functions of long noncoding RNAs in the nucleus. Nucleus (2016) 0.76
Triple helix-interacting proteins and cancer. OA Mol Oncol (2013) 0.76
Exploring the stability of long intergenic non-coding RNA in K562 cells by comparative studies of RNA-Seq datasets. Biol Direct (2014) 0.76
Pan-cancer transcriptomic analysis associates long non-coding RNAs with key mutational driver events. Nat Commun (2016) 0.75
Conserved 3' UTR stem-loop structure in L1 and Alu transposons in human genome: possible role in retrotransposition. BMC Genomics (2016) 0.75
Natural antisense RNA promotes 3' end processing and maturation of MALAT1 lncRNA. Nucleic Acids Res (2016) 0.75
HER3 and LINC00052 interplay promotes tumor growth in breast cancer. Oncotarget (2016) 0.75
RNA modifications and structures cooperate to guide RNA-protein interactions. Nat Rev Mol Cell Biol (2017) 0.75
A magnesium-induced triplex pre-organizes the SAM-II riboswitch. PLoS Comput Biol (2017) 0.75
Methyltransferase-like protein 16 binds the 3'-terminal triple helix of MALAT1 long noncoding RNA. Proc Natl Acad Sci U S A (2016) 0.75
Malat1 regulates myogenic differentiation and muscle regeneration through modulating MyoD transcriptional activity. Cell Discov (2017) 0.75
Emerging roles for long noncoding RNAs in skeletal biology and disease. Connect Tissue Res (2016) 0.75
Ribozyme Mediated gRNA Generation for In Vitro and In Vivo CRISPR/Cas9 Mutagenesis. PLoS One (2016) 0.75
Guide RNA engineering for versatile Cas9 functionality. Nucleic Acids Res (2016) 0.75
Understanding the Functions of Long Non-Coding RNAs through Their Higher-Order Structures. Int J Mol Sci (2016) 0.75
Targeted CRISPR disruption reveals a role for RNase MRP RNA in human preribosomal RNA processing. Genes Dev (2017) 0.75
The mutant p53-ID4 complex controls VEGFA isoforms by recruiting lncRNA MALAT1. EMBO Rep (2017) 0.75
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression. Genes Dev (2017) 0.75
The More the Merrier-Complexity in Long Non-Coding RNA Loci. Front Endocrinol (Lausanne) (2017) 0.75
Intronless β-Globin Reporter: A Tool for Studying Nuclear RNA Stability Elements. Methods Mol Biol (2016) 0.75
Dicer loss and recovery induce an oncogenic switch driven by transcriptional activation of the oncofetal Imp1-3 family. Genes Dev (2017) 0.75
MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17
Transcriptional maps of 10 human chromosomes at 5-nucleotide resolution. Science (2005) 16.82
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis. Microbiol Mol Biol Rev (1999) 11.32
Ribosome profiling of mouse embryonic stem cells reveals the complexity and dynamics of mammalian proteomes. Cell (2011) 10.56
Long noncoding RNAs: functional surprises from the RNA world. Genes Dev (2009) 9.14
The nuclear-retained noncoding RNA MALAT1 regulates alternative splicing by modulating SR splicing factor phosphorylation. Mol Cell (2010) 8.66
Cryptic pol II transcripts are degraded by a nuclear quality control pathway involving a new poly(A) polymerase. Cell (2005) 8.55
Whole-genome analysis informs breast cancer response to aromatase inhibition. Nature (2012) 8.03
MALAT-1, a novel noncoding RNA, and thymosin beta4 predict metastasis and survival in early-stage non-small cell lung cancer. Oncogene (2003) 7.90
Mechanism and regulation of mRNA polyadenylation. Genes Dev (1997) 7.48
RNA exosome depletion reveals transcription upstream of active human promoters. Science (2008) 6.80
A screen for nuclear transcripts identifies two linked noncoding RNAs associated with SC35 splicing domains. BMC Genomics (2007) 6.28
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell (2009) 5.99
Methylation protects miRNAs and siRNAs from a 3'-end uridylation activity in Arabidopsis. Curr Biol (2005) 5.99
A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol Cell Biol (1987) 5.66
Metabolism and regulation of canonical histone mRNAs: life without a poly(A) tail. Nat Rev Genet (2008) 5.42
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
RNA-quality control by the exosome. Nat Rev Mol Cell Biol (2006) 5.26
MEN epsilon/beta nuclear-retained non-coding RNAs are up-regulated upon muscle differentiation and are essential components of paraspeckles. Genome Res (2008) 5.06
Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation. Mol Cell (2009) 4.57
3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. Cell (2008) 4.54
ncRNA- and Pc2 methylation-dependent gene relocation between nuclear structures mediates gene activation programs. Cell (2011) 4.26
New perspectives on connecting messenger RNA 3' end formation to transcription. Curr Opin Cell Biol (2004) 4.04
Structural basis of glmS ribozyme activation by glucosamine-6-phosphate. Science (2006) 3.94
MicroRNAs can generate thresholds in target gene expression. Nat Genet (2011) 3.90
A large noncoding RNA is a marker for murine hepatocellular carcinomas and a spectrum of human carcinomas. Oncogene (2006) 3.89
Automated de novo prediction of native-like RNA tertiary structures. Proc Natl Acad Sci U S A (2007) 3.87
The Xist RNA gene evolved in eutherians by pseudogenization of a protein-coding gene. Science (2006) 3.50
Degradation of histone mRNA requires oligouridylation followed by decapping and simultaneous degradation of the mRNA both 5' to 3' and 3' to 5'. Genes Dev (2008) 3.30
Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation. Med Oncol (2011) 3.24
Atomic accuracy in predicting and designing noncanonical RNA structure. Nat Methods (2010) 3.07
Uridine addition after microRNA-directed cleavage. Science (2004) 2.96
Genomewide characterization of non-polyadenylated RNAs. Genome Biol (2011) 2.92
GW182 proteins directly recruit cytoplasmic deadenylase complexes to miRNA targets. Mol Cell (2011) 2.80
Peptides encoded by short ORFs control development and define a new eukaryotic gene family. PLoS Biol (2007) 2.54
The lncRNA Malat1 is dispensable for mouse development but its transcription plays a cis-regulatory role in the adult. Cell Rep (2012) 2.45
Decapping is preceded by 3' uridylation in a novel pathway of bulk mRNA turnover. Nat Struct Mol Biol (2009) 2.30
Spliceosomal cleavage generates the 3' end of telomerase RNA. Nature (2008) 1.93
PABP and the poly(A) tail augment microRNA repression by facilitated miRISC binding. Nat Struct Mol Biol (2012) 1.91
Loss of the abundant nuclear non-coding RNA MALAT1 is compatible with life and development. RNA Biol (2012) 1.90
Malat1 is not an essential component of nuclear speckles in mice. RNA (2012) 1.90
Poly(A) tail recognition by a viral RNA element through assembly of a triple helix. Science (2010) 1.73
Cloning of an Alpha-TFEB fusion in renal tumors harboring the t(6;11)(p21;q13) chromosome translocation. Proc Natl Acad Sci U S A (2003) 1.73
Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing. EMBO J (2010) 1.64
Triple-helix structure in telomerase RNA contributes to catalysis. Nat Struct Mol Biol (2008) 1.62
Noncoding RNA gene silencing through genomic integration of RNA destabilizing elements using zinc finger nucleases. Genome Res (2011) 1.59
3' Terminal oligo U-tract-mediated stimulation of decapping. RNA (2007) 1.59
Upregulation of the transcription factor TFEB in t(6;11)(p21;q13)-positive renal cell carcinomas due to promoter substitution. Hum Mol Genet (2003) 1.47
Metabolite recognition principles and molecular mechanisms underlying riboswitch function. Annu Rev Biophys (2012) 1.47
Poly A- transcripts expressed in HeLa cells. PLoS One (2008) 1.42
DNA sequence of the translocation breakpoints in undifferentiated embryonal sarcoma arising in mesenchymal hamartoma of the liver harboring the t(11;19)(q11;q13.4) translocation. Genes Chromosomes Cancer (2007) 1.40
Conservation of a triple-helix-forming RNA stability element in noncoding and genomic RNAs of diverse viruses. Cell Rep (2012) 1.34
Identification of cis- and trans-acting factors involved in the localization of MALAT-1 noncoding RNA to nuclear speckles. RNA (2012) 1.33
tRNAs marked with CCACCA are targeted for degradation. Science (2011) 1.30
Novel features in the tRNA-like world of plant viral RNAs. Cell Mol Life Sci (2001) 1.29
PABP is not essential for microRNA-mediated translational repression and deadenylation in vitro. EMBO J (2011) 1.29
RNase P RNA mediated cleavage: substrate recognition and catalysis. Biochimie (2007) 1.28
A viral nuclear noncoding RNA binds re-localized poly(A) binding protein and is required for late KSHV gene expression. PLoS Pathog (2011) 1.17
Translational inhibition by deadenylation-independent mechanisms is central to microRNA-mediated silencing in zebrafish. Proc Natl Acad Sci U S A (2012) 1.17
An unexpected ending: noncanonical 3' end processing mechanisms. RNA (2009) 1.13
Alternative mRNA polyadenylation in eukaryotes: an effective regulator of gene expression. Wiley Interdiscip Rev RNA (2011) 1.06
Widespread RNA 3'-end oligouridylation in mammals. RNA (2012) 1.04
Argonaute2 is the catalytic engine of mammalian RNAi. Science (2004) 22.86
Specificity of microRNA target selection in translational repression. Genes Dev (2004) 21.14
Predictive identification of exonic splicing enhancers in human genes. Science (2002) 16.86
Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38
siRNAs can function as miRNAs. Genes Dev (2003) 16.08
Histone H3K27ac separates active from poised enhancers and predicts developmental state. Proc Natl Acad Sci U S A (2010) 15.13
MicroRNA sponges: competitive inhibitors of small RNAs in mammalian cells. Nat Methods (2007) 13.94
Embryonic stem cell-specific MicroRNAs. Dev Cell (2003) 13.05
Crystal structure of Argonaute and its implications for RISC slicer activity. Science (2004) 12.48
Targeted deletion reveals essential and overlapping functions of the miR-17 through 92 family of miRNA clusters. Cell (2008) 12.29
c-Myc regulates transcriptional pause release. Cell (2010) 11.64
Proliferating cells express mRNAs with shortened 3' untranslated regions and fewer microRNA target sites. Science (2008) 11.33
Divergent transcription from active promoters. Science (2008) 11.03
Cre-lox-regulated conditional RNA interference from transgenes. Proc Natl Acad Sci U S A (2004) 9.33
Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA (2003) 8.07
Gene silencing in mammals by small interfering RNAs. Nat Rev Genet (2002) 7.80
Killing the messenger: short RNAs that silence gene expression. Nat Rev Mol Cell Biol (2003) 7.38
Analysis of the C. elegans Argonaute family reveals that distinct Argonautes act sequentially during RNAi. Cell (2006) 7.14
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol (2003) 6.90
Suppression of non-small cell lung tumor development by the let-7 microRNA family. Proc Natl Acad Sci U S A (2008) 6.89
Short RNAs repress translation after initiation in mammalian cells. Mol Cell (2006) 6.70
Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol (2005) 6.64
siRNA-directed inhibition of HIV-1 infection. Nat Med (2002) 6.36
Roles for microRNAs in conferring robustness to biological processes. Cell (2012) 6.32
MicroRNA-responsive 'sensor' transgenes uncover Hox-like and other developmentally regulated patterns of vertebrate microRNA expression. Nat Genet (2004) 6.11
TAZ, a transcriptional modulator of mesenchymal stem cell differentiation. Science (2005) 5.56
miRNA profiling of naïve, effector and memory CD8 T cells. PLoS One (2007) 5.43
RNA sequence analysis defines Dicer's role in mouse embryonic stem cells. Proc Natl Acad Sci U S A (2007) 5.26
Mechanism of DNA translocation in a replicative hexameric helicase. Nature (2006) 4.91
Dynamic regulation of miRNA expression in ordered stages of cellular development. Genes Dev (2007) 4.79
MicroRNA functions in stress responses. Mol Cell (2010) 4.46
Quantitative analysis of Argonaute protein reveals microRNA-dependent localization to stress granules. Proc Natl Acad Sci U S A (2006) 4.02
Slicer and the argonautes. Nat Chem Biol (2007) 3.99
The RNAi revolution. Nature (2004) 3.96
Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132. Neuron (2010) 3.96
MicroRNAs can generate thresholds in target gene expression. Nat Genet (2011) 3.90
Structural basis for the EBA-175 erythrocyte invasion pathway of the malaria parasite Plasmodium falciparum. Cell (2005) 3.79
RESCUE-ESE identifies candidate exonic splicing enhancers in vertebrate exons. Nucleic Acids Res (2004) 3.70
RNA interference of influenza virus production by directly targeting mRNA for degradation and indirectly inhibiting all viral RNA transcription. Proc Natl Acad Sci U S A (2003) 3.48
Gene silencing using micro-RNA designed hairpins. RNA (2002) 3.21
microRNAs: a safeguard against turmoil? Cell (2007) 3.11
14-3-3sigma controls mitotic translation to facilitate cytokinesis. Nature (2007) 2.98
MicroRNA sponges: progress and possibilities. RNA (2010) 2.96
Genome-wide identification of Ago2 binding sites from mouse embryonic stem cells with and without mature microRNAs. Nat Struct Mol Biol (2011) 2.85
The structure of human argonaute-2 in complex with miR-20a. Cell (2012) 2.83
Single nucleotide polymorphism-based validation of exonic splicing enhancers. PLoS Biol (2004) 2.77
Divergent transcription of long noncoding RNA/mRNA gene pairs in embryonic stem cells. Proc Natl Acad Sci U S A (2013) 2.75
Characterization of a highly variable eutherian microRNA gene. RNA (2005) 2.72
Research data in the digital age. Science (2009) 2.65
Promoter directionality is controlled by U1 snRNP and polyadenylation signals. Nature (2013) 2.63
Emerging roles for natural microRNA sponges. Curr Biol (2010) 2.62
Divergent transcription: a new feature of active promoters. Cell Cycle (2009) 2.50
Argonaute slicing is required for heterochromatic silencing and spreading. Science (2006) 2.48
On helicases and other motor proteins. Curr Opin Struct Biol (2008) 2.43
Poly(ADP-ribose) regulates stress responses and microRNA activity in the cytoplasm. Mol Cell (2011) 2.33
Sustained small interfering RNA-mediated human immunodeficiency virus type 1 inhibition in primary macrophages. J Virol (2003) 2.26
Comparison of siRNA-induced off-target RNA and protein effects. RNA (2007) 2.22
Transcriptional silencing of a transgene by RNAi in the soma of C. elegans. Genes Dev (2005) 2.16
RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genes. Mol Cell Biol (2003) 2.07
1918 flu and responsible science. Science (2005) 2.05
Proliferation and tumorigenesis of a murine sarcoma cell line in the absence of DICER1. Cancer Cell (2012) 2.04
Regulation of CD44 alternative splicing by SRm160 and its potential role in tumor cell invasion. Mol Cell Biol (2006) 1.99
The structural biochemistry of Zucchini implicates it as a nuclease in piRNA biogenesis. Nature (2012) 1.97
Small interfering RNA-mediated gene silencing in T lymphocytes. J Immunol (2002) 1.90
A system for Cre-regulated RNA interference in vivo. Proc Natl Acad Sci U S A (2008) 1.87
Opposing functions of TFII-I spliced isoforms in growth factor-induced gene expression. Mol Cell (2006) 1.81
Antisense RNA polymerase II divergent transcripts are P-TEFb dependent and substrates for the RNA exosome. Proc Natl Acad Sci U S A (2011) 1.77
Pyruvate kinase M2-specific siRNA induces apoptosis and tumor regression. J Exp Med (2012) 1.76
The role of miRNAs in regulating gene expression networks. J Mol Biol (2013) 1.74
High-affinity binding of Chp1 chromodomain to K9 methylated histone H3 is required to establish centromeric heterochromatin. Mol Cell (2009) 1.65
A positive feedback loop couples Ras activation and CD44 alternative splicing. Genes Dev (2006) 1.60
Strategies for protein coexpression in Escherichia coli. Nat Methods (2006) 1.58
Molecular biology. A circuitous route to noncoding RNA. Science (2013) 1.47
Crystal structures of two intermediates in the assembly of the papillomavirus replication initiation complex. EMBO J (2002) 1.45
Transcription-coupled and DNA damage-dependent ubiquitination of RNA polymerase II in vitro. Proc Natl Acad Sci U S A (2002) 1.45
Argonaute and RNA--getting into the groove. Curr Opin Struct Biol (2006) 1.35
Mir-290-295 deficiency in mice results in partially penetrant embryonic lethality and germ cell defects. Proc Natl Acad Sci U S A (2011) 1.33
A latent pro-survival function for the mir-290-295 cluster in mouse embryonic stem cells. PLoS Genet (2011) 1.31
tRNAs marked with CCACCA are targeted for degradation. Science (2011) 1.30
Embryonic lethality, decreased erythropoiesis, and defective octamer-dependent promoter activation in Oct-1-deficient mice. Mol Cell Biol (2004) 1.30
Functional delivery of siRNA in mice using dendriworms. ACS Nano (2009) 1.27
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice. Blood (2011) 1.26
The octamer binding transcription factor Oct-1 is a stress sensor. Cancer Res (2005) 1.22
Argonautes confront new small RNAs. Curr Opin Chem Biol (2007) 1.20
Divergent transcription: a driving force for new gene origination? Cell (2013) 1.20
Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells. Proc Natl Acad Sci U S A (2010) 1.20
In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. RNA (2012) 1.20
The discovery of split genes and RNA splicing. Trends Biochem Sci (2005) 1.19
Eukaryotic Argonautes come into focus. Trends Biochem Sci (2013) 1.19
Rbfox2 controls autoregulation in RNA-binding protein networks. Genes Dev (2014) 1.18
The making of a slicer: activation of human Argonaute-1. Cell Rep (2013) 1.15
NADP regulates the yeast GAL induction system. Science (2008) 1.15
Characterization of the short RNAs bound by the P19 suppressor of RNA silencing in mouse embryonic stem cells. RNA (2006) 1.13
Effect of nanoparticle conjugation on gene silencing by RNA interference. J Am Chem Soc (2010) 1.11
Small RNA regulators of gene expression. Cell (2008) 1.10
Regulation of immunoglobulin promoter activity by TFII-I class transcription factors. J Biol Chem (2003) 1.09
PDCD2 is a negative regulator of HCF-1 (C1). Oncogene (2002) 1.08
B cell development and immunoglobulin transcription in Oct-1-deficient mice. Proc Natl Acad Sci U S A (2004) 1.03
Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes. Proc Natl Acad Sci U S A (2005) 1.02