Published in Mol Cell Biol on April 01, 1986
A recombinant murine retrovirus for simian virus 40 large T cDNA transforms mouse fibroblasts to anchorage-independent growth. J Virol (1986) 1.68
Mutations which affect the inhibition of protein phosphatase 2A by simian virus 40 small-t antigen in vitro decrease viral transformation. J Virol (1994) 1.42
Simian virus 40 small t antigen cooperates with mitogen-activated kinases to stimulate AP-1 activity. Mol Cell Biol (1994) 1.27
Simian virus 40 small tumor antigen and an amino-terminal domain of large tumor antigen share a common transforming function. Proc Natl Acad Sci U S A (1990) 1.27
Purification and functional properties of simian virus 40 large and small T antigens overproduced in insect cells. J Virol (1988) 1.14
Mutational analysis of simian virus 40 small-t antigen. J Virol (1990) 1.13
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Construction and characterization of an SV40 mutant defective in nuclear transport of T antigen. Cell (1984) 5.81
Mutants of SV40 with an altered small t protein are reduced in their ability to transform cells. Cell (1978) 5.23
DNA infectivity and the induction of host DNA synthesis with temperature-sensitive mutants of simian virus 40. J Virol (1975) 5.22
Patterns of organization of actin and myosin in normal and transformed cultured cells. Proc Natl Acad Sci U S A (1975) 4.86
New region of the simian virus 40 genome required for efficient viral transformation. Proc Natl Acad Sci U S A (1978) 4.24
Temperature-sensitive changes in surface modulating assemblies of fibroblasts transformed by mutants of Rous sarcoma virus. Proc Natl Acad Sci U S A (1976) 3.29
Amino acid sequence homology between polyoma and SV40 tumour antigens deduced from nucleotide sequences. Nature (1978) 3.11
Comparisons of two early gene functions essential for transformation in polyoma virus and SV-40. Virology (1979) 2.64
Biological activity of purified simian virus 40 T antigen proteins. Proc Natl Acad Sci U S A (1978) 2.54
Cellular proteins associated with simian virus 40 early gene products in newly infected cells. J Virol (1979) 2.44
Fragments of the simian virus 40 transforming gene facilitate transformation of rat embryo cells. Proc Natl Acad Sci U S A (1982) 2.29
Properties of simian virus 40 small t antigen overproduced in bacteria. J Virol (1981) 2.08
Construction and functional characterization of polyomavirus genomes that separately encode the three early proteins. J Virol (1984) 2.02
A fragment of the SV40 large T-antigen gene transforms. Nature (1982) 1.82
Role of small t antigen in the acute transforming activity of SV40. Cell (1982) 1.76
Cytoskeletal F-actin patterns quantitated with fluorescein isothiocyanate-phalloidin in normal and transformed cells. Proc Natl Acad Sci U S A (1980) 1.73
Simian virus 40 small-t protein is required for loss of actin cable networks in rat cells. J Virol (1980) 1.68
Nucleotide sequence of the BK virus DNA segment encoding small t antigen. Proc Natl Acad Sci U S A (1979) 1.67
Purification of biologically active simian virus 40 small tumor antigen. Proc Natl Acad Sci U S A (1983) 1.61
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Simian virus 40 t antigen affects the sensitivity of cellular DNA synthesis to theophylline. J Virol (1979) 1.43
Genomic structure of human polyoma virus JC: nucleotide sequence of the region containing replication origin and small-T-antigen gene. J Virol (1983) 1.36
Transformation by purified early genes of simian virus 40. Virology (1984) 1.31
Tubulin and actin in paired nonneoplastic and spontaneously transformed neoplastic cell lines in vitro: fluorescent antibody studies. Cell (1978) 1.22
Monoclonal antibody to simian virus 40 small t. J Virol (1984) 1.08
Localization of the simian virus 40 small t antigen in the nucleus and cytoplasm of monkey and mouse cells. J Virol (1984) 1.07
A simian virus 40 dl884/tsA58 double mutant is temperature sensitive for abortive transformation. J Virol (1983) 1.04
Stimulation of host centriolar antigen in TC7 cells by simian virus 40: requirement for RNA and protein syntheses and an intact simian virus 40 small-t gene function. J Virol (1982) 0.88
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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene. Cell (1988) 12.69
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Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science (1985) 8.72
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Association of BRCA1 with Rad51 in mitotic and meiotic cells. Cell (1997) 8.28
Functional interactions of the retinoblastoma protein with mammalian D-type cyclins. Cell (1993) 7.19
Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell (1998) 6.73
Identification of cellular proteins that can interact specifically with the T/E1A-binding region of the retinoblastoma gene product. Cell (1991) 6.55
The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell (1989) 6.43
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High-pressure liquid chromatography in polynucleotide synthesis. Biochemistry (1978) 5.98
Dynamic changes of BRCA1 subnuclear location and phosphorylation state are initiated by DNA damage. Cell (1997) 5.92
Evaluation of normalization procedures for oligonucleotide array data based on spiked cRNA controls. Genome Biol (2001) 5.61
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection. Science (2001) 5.58
Transcription profiling-based identification of Staphylococcus aureus genes regulated by the agr and/or sarA loci. J Bacteriol (2001) 5.57
E2F-1 functions in mice to promote apoptosis and suppress proliferation. Cell (1996) 5.26
Activation of hypoxia-inducible transcription factor depends primarily upon redox-sensitive stabilization of its alpha subunit. J Biol Chem (1996) 5.15
Binding and modulation of p53 by p300/CBP coactivators. Nature (1997) 5.12
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis. Proc Natl Acad Sci U S A (1994) 5.11
The transcription factor E2F interacts with the retinoblastoma product and a p107-cyclin A complex in a cell cycle-regulated manner. Cell (1992) 5.05
BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function. Cell (2001) 5.05
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
An essential role for p300/CBP in the cellular response to hypoxia. Proc Natl Acad Sci U S A (1996) 4.57
Identification of a growth suppression domain within the retinoblastoma gene product. Genes Dev (1992) 4.56
A family of transcriptional adaptor proteins targeted by the E1A oncoprotein. Nature (1995) 4.40
In search of the tumour-suppressor functions of BRCA1 and BRCA2. Nature (2000) 4.38
The T/E1A-binding domain of the retinoblastoma product can interact selectively with a sequence-specific DNA-binding protein. Cell (1991) 4.24
Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase. Cell (1994) 4.01
Spinocerebellar ataxia type 5 in a family descended from the grandparents of President Lincoln maps to chromosome 11. Nat Genet (1994) 3.89
Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature (1996) 3.88
SV40 large T antigen binds preferentially to an underphosphorylated member of the retinoblastoma susceptibility gene product family. Cell (1989) 3.88
Stable interaction between the products of the BRCA1 and BRCA2 tumor suppressor genes in mitotic and meiotic cells. Mol Cell (1998) 3.86
Genetic analysis of BRCA1 function in a defined tumor cell line. Mol Cell (1999) 3.83
Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med (2000) 3.72
Mapping of SV40 DNA replication origin region binding sites for the SV40 T antigen by protection against exonuclease III digestion. Cell (1980) 3.62
Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation. Cell (1990) 3.61
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature (2000) 3.48
Molecular cloning, chromosomal mapping, and expression of the cDNA for p107, a retinoblastoma gene product-related protein. Cell (1991) 3.47
The nuclear hormone receptor coactivator SRC-1 is a specific target of p300. Proc Natl Acad Sci U S A (1996) 3.43
Self-excising retroviral vectors encoding the Cre recombinase overcome Cre-mediated cellular toxicity. Mol Cell (2001) 3.43
Interaction between the retinoblastoma protein and the oncoprotein MDM2. Nature (1995) 3.39
lac repressor can regulate expression from a hybrid SV40 early promoter containing a lac operator in animal cells. Cell (1987) 3.33
Infectious C-type virus isolated from a baboon placenta. Nature (1974) 3.32
Stringent regulation of stably integrated chloramphenicol acetyl transferase genes by E. coli lac repressor in monkey cells. Cell (1988) 3.29
p300/MDM2 complexes participate in MDM2-mediated p53 degradation. Mol Cell (1998) 3.27
Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev (1996) 3.24
Gene dose-dependent control of hematopoiesis and hematologic tumor suppression by CBP. Genes Dev (2000) 3.24
E1A-associated p300 and CREB-associated CBP belong to a conserved family of coactivators. Cell (1994) 3.24
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The retinoblastoma susceptibility gene product undergoes cell cycle-dependent dephosphorylation and binding to and release from SV40 large T. Cell (1990) 3.19
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The p400 complex is an essential E1A transformation target. Cell (2001) 3.05
E2F-4, a new member of the E2F transcription factor family, interacts with p107. Genes Dev (1994) 3.05
Functional interaction between E2F-4 and p130: evidence for distinct mechanisms underlying growth suppression by different retinoblastoma protein family members. Genes Dev (1995) 3.02
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Decorin-binding adhesins from Borrelia burgdorferi. Mol Microbiol (1998) 2.85
An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120. Cell (1989) 2.78
Interaction of the protein kinase Raf-1 with 14-3-3 proteins. Science (1994) 2.74
Cyclin A-kinase regulation of E2F-1 DNA binding function underlies suppression of an S phase checkpoint. Cell (1995) 2.70
Binding to DNA and the retinoblastoma gene product promoted by complex formation of different E2F family members. Science (1993) 2.70
Involvement of the cell-cycle inhibitor Cip1/WAF1 and the E1A-associated p300 protein in terminal differentiation. Proc Natl Acad Sci U S A (1995) 2.70
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Identification of regions of the SV40 genome which contain preferred SV40 T antigen-binding sites. Cell (1976) 2.47
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Association of p300 and CBP with simian virus 40 large T antigen. Mol Cell Biol (1996) 2.40
Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins. Science (1992) 2.39
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Specific enzymatic dephosphorylation of the retinoblastoma protein. Mol Cell Biol (1993) 2.37
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Molecular characterization and expression of the gene encoding human erythroid-potentiating activity. Nature (1985) 2.25
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Interaction of partially purified simian virus 40 T antigen with circular viral DNA molecules. Proc Natl Acad Sci U S A (1975) 2.17
Consensus topography in the ATP binding site of the simian virus 40 and polyomavirus large tumor antigens. Proc Natl Acad Sci U S A (1987) 2.15
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SV40 small t antigen enhances the transformation activity of limiting concentrations of SV40 large T antigen. Cell (1987) 2.13
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