Published in Cell on May 01, 1975
Anatomy of herpes simplex virus (HSV) DNA. X. Mapping of viral genes by analysis of polypeptides and functions specified by HSV-1 X HSV-2 recombinants. J Virol (1978) 11.19
Physical mapping of herpes simplex virus-induced polypeptides. J Virol (1978) 6.08
Anatomy of herpes simplex virus DNA. IX. Apparent exclusion of some parental DNA arrangements in the generation of intertypic (HSV-1 X HSV-2) recombinants. J Virol (1977) 5.98
Recombinants between herpes simplex virus types 1 and 2: analyses of genome structures and expression of immediate early polypeptides. J Virol (1978) 4.87
Purification of specific adenovirus 2 RNAs by preparative hybridization and selective thermal elution. Nucleic Acids Res (1979) 2.78
Direct biochemical mapping of eukaryotic viral DNA by means of a linked transcription-translation cell-free system. Proc Natl Acad Sci U S A (1976) 2.17
Groups of adenovirus type 2 mRNA's derived from a large primary transcript: probable nuclear origin and possible common 3' ends. J Virol (1978) 2.06
Electron microscopy of late adenovirus type 2 mRNA hybridized to double-stranded viral DNA. J Virol (1977) 1.45
Species identification and genome mapping of cytoplasmic adenovirus type 2 RNAs synthesized late in infection. J Virol (1977) 1.43
Molecular evolution of human species D adenoviruses. Infect Genet Evol (2011) 1.25
Assembly intermediates among adenovirus type 5 temperature-sensitive mutants. J Virol (1978) 1.20
Restriction Map of Rachiplusia ou and Rachiplusia ou-Autographa californica Baculovirus Recombinants. J Virol (1980) 1.18
Characterization of a temperature-sensitive, hexon transport mutant of type 5 adenovirus. J Virol (1976) 1.17
Simian virus 40-specific polypeptides in AD2+ ND1- and Ad2+ ND4-infected cells. J Virol (1976) 1.13
The revolution in viral genomics as exemplified by the bioinformatic analysis of human adenoviruses. Viruses (2010) 0.88
Physical mapping of adenovirus type 2 temperature-sensitive mutations by restriction endonuclease analysis of interserotypic recombinants. J Virol (1982) 0.84
Sizing and mapping of early adenovirus mRNAs by gel electrophoresis of S1 endonuclease-digested hybrids. Cell (1977) 61.24
Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry (1973) 43.61
DNA-dependent transcription of adenovirus genes in a soluble whole-cell extract. Proc Natl Acad Sci U S A (1980) 24.21
RNAi: double-stranded RNA directs the ATP-dependent cleavage of mRNA at 21 to 23 nucleotide intervals. Cell (2000) 20.32
A protein interaction map of Drosophila melanogaster. Science (2003) 20.06
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. I. Structure of F-prime factors. J Mol Biol (1972) 19.88
Protein folding in the cell. Nature (1992) 19.60
Spliced early mRNAs of simian virus 40. Proc Natl Acad Sci U S A (1978) 18.67
An outbreak of multidrug-resistant tuberculosis among hospitalized patients with the acquired immunodeficiency syndrome. N Engl J Med (1992) 18.11
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (1986) 14.34
Spliced segments at the 5' terminus of adenovirus 2 late mRNA. Proc Natl Acad Sci U S A (1977) 14.34
Pre-early adenovirus 5 gene product regulates synthesis of early viral messenger RNAs. Cell (1979) 12.83
The arrangement of simian virus 40 sequences in the DNA of transformed cells. Cell (1976) 12.60
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors. J Mol Biol (1973) 11.40
Structure of the adenovirus 2 early mRNAs. Cell (1978) 10.54
An RNA polymerase II transcription factor binds to an upstream element in the adenovirus major late promoter. Cell (1985) 10.06
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet (2013) 9.46
Adenovirus E1b-58kd tumor antigen and SV40 large tumor antigen are physically associated with the same 54 kd cellular protein in transformed cells. Cell (1982) 9.27
Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Expression of wild-type and mutant forms of influenza hemagglutinin: the role of folding in intracellular transport. Cell (1986) 9.16
Recognition of cap structure in splicing in vitro of mRNA precursors. Cell (1984) 8.67
A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
The integrated state of viral DNA in SV40-transformed cells. Proc Natl Acad Sci U S A (1968) 8.38
Amount of viral DNA in the genome of cells transformed by adenovirus type 2. J Mol Biol (1973) 8.28
Mapping temperature-sensitive and host-range mutations of adenovirus type 5 by marker rescue. Virology (1978) 8.28
Speculations on RNA splicing. Cell (1981) 8.28
Targeted mRNA degradation by double-stranded RNA in vitro. Genes Dev (1999) 8.21
GPs in principle but not in practice: a study of vocationally trained doctors not currently working as principals. BMJ (1995) 8.09
Electrophoretic separation of complexes involved in the splicing of precursors to mRNAs. Cell (1986) 8.06
Molecular cloning of an enhancer binding protein: isolation by screening of an expression library with a recognition site DNA. Cell (1988) 8.00
The presence of malfolded proteins in the endoplasmic reticulum signals the induction of glucose-regulated proteins. Nature (1988) 7.98
Cleavage of adenovirus type 2 DNA into six unique fragments by endonuclease R-RI. Proc Natl Acad Sci U S A (1973) 7.75
Splicing of messenger RNA precursors. Science (1987) 7.61
Transcription of Simian virus 40. I. Separation of the strands of SV40 DNA and hybridization of the separated strands to RNA extracted from lytically infected and transformed cells. J Mol Biol (1972) 7.49
A single polypeptide possesses the binding and transcription activities of the adenovirus major late transcription factor. Mol Cell Biol (1986) 7.49
Interactions between small nuclear ribonucleoprotein particles in formation of spliceosomes. Cell (1987) 7.44
Regulation by HIV Rev depends upon recognition of splice sites. Cell (1989) 7.13
In vitro transcription of adenovirus. J Virol (1981) 7.06
A transmembrane protein with a cdc2+/CDC28-related kinase activity is required for signaling from the ER to the nucleus. Cell (1993) 6.82
A quantitative approach to perceived health status: a validation study. J Epidemiol Community Health (1980) 6.29
A multicomponent complex is involved in the splicing of messenger RNA precursors. Cell (1985) 6.27
Evolutionary fates and origins of U12-type introns. Mol Cell (1998) 6.25
The POU domain: a large conserved region in the mammalian pit-1, oct-1, oct-2, and Caenorhabditis elegans unc-86 gene products. Genes Dev (1988) 6.23
Disruption of p53 in human cancer cells alters the responses to therapeutic agents. J Clin Invest (1999) 6.13
Direct inhibition of the signaling functions of the mammalian target of rapamycin by the phosphoinositide 3-kinase inhibitors, wortmannin and LY294002. EMBO J (1996) 6.08
Site-specific modification of pre-mRNA: the 2'-hydroxyl groups at the splice sites. Science (1992) 5.87
Human CCAAT-binding proteins have heterologous subunits. Cell (1988) 5.81
A high-efficiency HeLa cell nuclear transcription extract. DNA (1988) 5.81
Heterogeneous nuclear ribonucleoproteins: role in RNA splicing. Science (1986) 5.52
Accurate cleavage and polyadenylation of exogenous RNA substrate. Cell (1985) 5.27
Prenatal screening for Down's syndrome with use of maternal serum markers. N Engl J Med (1992) 5.21
Lariat RNA's as intermediates and products in the splicing of messenger RNA precursors. Science (1984) 5.11
Binding of a nuclear factor to a regulatory sequence in the promoter of the mouse H-2Kb class I major histocompatibility gene. Mol Cell Biol (1987) 5.05
The Nottingham Health Profile: subjective health status and medical consultations. Soc Sci Med A (1981) 5.02
Mapping of adenovirus 2 RNA sequences in lytically infected cells and transformed cell lines. Cold Spring Harb Symp Quant Biol (1975) 4.87
Two transcription factors, NF-kappa B and H2TF1, interact with a single regulatory sequence in the class I major histocompatibility complex promoter. Proc Natl Acad Sci U S A (1988) 4.83
T antigen repression of SV40 early transcription from two promoters. Cell (1981) 4.83
Separation and characterization of factors mediating accurate transcription by RNA polymerase II. J Biol Chem (1982) 4.71
Influence of substrate wettability on the attachment of marine bacteria to various surfaces. Appl Microbiol (1975) 4.70
On the origin of RNA splicing and introns. Cell (1985) 4.70
Sequence heterogeneity in closed simian virus 40 deoxyribonucleic acid. J Virol (1972) 4.69
Splicing of adenovirus RNA in a cell-free transcription system. Proc Natl Acad Sci U S A (1983) 4.69
Origin-defective mutants of SV40. Cold Spring Harb Symp Quant Biol (1980) 4.64
Identification and purification of a 62,000-dalton protein that binds specifically to the polypyrimidine tract of introns. Genes Dev (1989) 4.53
Studies on simian virus 40 excision from cellular chromosomes. Cold Spring Harb Symp Quant Biol (1979) 4.45
Splicing of messenger RNA precursors is inhibited by antisera to small nuclear ribonucleoprotein. Cell (1983) 4.42
Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proc Natl Acad Sci U S A (1981) 4.42
The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature (1982) 4.42
Host-range mutants of adenovirus type 5 defective for growth in HeLa cells. Virology (1977) 4.40
Viral DNA in transformed cells. I. A study of the sequences of adenovirus 2 DNA in a line of transformed rat cells using specific fragments of the viral genome. J Mol Biol (1974) 4.30
S. cerevisiae encodes an essential protein homologous in sequence and function to mammalian BiP. Cell (1989) 4.28
HIV-1 Tat protein promotes formation of more-processive elongation complexes. EMBO J (1991) 4.18
The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains. Genes Dev (1988) 4.14
In vitro transcription: whole-cell extract. Methods Enzymol (1983) 4.07
Affinity chromatography of splicing complexes: U2, U5, and U4 + U6 small nuclear ribonucleoprotein particles in the spliceosome. Science (1986) 4.01
Messenger RNA splicing in vitro: an excised intervening sequence and a potential intermediate. Cell (1984) 4.00
An improved bacteriophage lambda vector: construction of model recombinants coding for kanamycin resistance. Gene (1977) 3.94
Function of a yeast TATA element-binding protein in a mammalian transcription system. Nature (1988) 3.91
Agarose slab-gel electrophoresis equipment. Anal Biochem (1975) 3.88
Cleavage maps of DNA from adenovirus types 2 and 5 by restriction endonucleases EcoRI and HpaI. Cold Spring Harb Symp Quant Biol (1975) 3.87
Transcription maps of adenovirus. Methods Enzymol (1980) 3.82
Change in use of asthma as a diagnostic label for wheezing illness in schoolchildren. BMJ (1989) 3.80
Viral dynamics of primary viremia and antiretroviral therapy in simian immunodeficiency virus infection. J Virol (1997) 3.79
Nucleotide sequence analysis of the leader segments in a cloned copy of adenovirus 2 fiber mRNA. Cell (1979) 3.78
DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. Cell (1993) 3.77
The extent of early viral replication is a critical determinant of the natural history of simian immunodeficiency virus infection. J Virol (1997) 3.77
RNA synthesis in isolated nuclei: in vitro initiation of adenovirus 2 major late mRNA precursor. Proc Natl Acad Sci U S A (1979) 3.75
Construction of influenza haemagglutinin genes that code for intracellular and secreted forms of the protein. Nature (1982) 3.74
The influence of dominance rank on the reproductive success of female chimpanzees. Science (1997) 3.74
Site-specific polyadenylation in a cell-free reaction. Cell (1984) 3.59
HIV-1 Tat protein trans-activates transcription in vitro. Cell (1990) 3.57
Characterization of cDNAs encoding the polypyrimidine tract-binding protein. Genes Dev (1991) 3.55
SV40 DNA transfection of cells in suspension: analysis of efficiency of transcription and translation of T-antigen. Gene (1981) 3.54
Defective transforming capacity of adenovirus type 5 host-range mutants. Virology (1978) 3.52