Published in Nature on March 23, 1995
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Transforming growth factor-beta 3 is required for secondary palate fusion. Nat Genet (1995) 4.46
M2 microglia and macrophages drive oligodendrocyte differentiation during CNS remyelination. Nat Neurosci (2013) 3.59
Regulation of muscle growth by multiple ligands signaling through activin type II receptors. Proc Natl Acad Sci U S A (2005) 3.52
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The orphan receptor ALK7 and the Activin receptor ALK4 mediate signaling by Nodal proteins during vertebrate development. Genes Dev (2001) 2.17
Activin receptor patterning of foregut organogenesis. Genes Dev (2000) 1.91
Activin type IIA and IIB receptors mediate Gdf11 signaling in axial vertebral patterning. Genes Dev (2002) 1.68
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Activin is an essential early mesenchymal signal in tooth development that is required for patterning of the murine dentition. Genes Dev (1998) 1.30
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Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1. Mol Endocrinol (2004) 1.22
Transforming growth factor β receptor type 1 is essential for female reproductive tract integrity and function. PLoS Genet (2011) 1.20
Activin in the brain modulates anxiety-related behavior and adult neurogenesis. PLoS One (2008) 1.14
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Conditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality. J Invest Dermatol (2010) 1.09
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Activin induces x-zone apoptosis that inhibits luteinizing hormone-dependent adrenocortical tumor formation in inhibin-deficient mice. Mol Cell Biol (2003) 1.07
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Reduced sperm count and normal fertility in male mice with targeted disruption of the ADP-ribosylation factor-like 4 (Arl4) gene. Mol Cell Biol (2002) 1.02
Activin and glucocorticoids synergistically activate follicle-stimulating hormone beta-subunit gene expression in the immortalized LbetaT2 gonadotrope cell line. Endocrinology (2006) 1.01
Activin bioactivity affects germ cell differentiation in the postnatal mouse testis in vivo. Biol Reprod (2010) 1.00
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Essential roles of inhibin beta A in mouse epididymal coiling. Proc Natl Acad Sci U S A (2007) 0.95
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Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn (2009) 0.94
Inhibin at 90: from discovery to clinical application, a historical review. Endocr Rev (2014) 0.91
MicroRNA-181a suppresses mouse granulosa cell proliferation by targeting activin receptor IIA. PLoS One (2013) 0.91
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Redirecting intracellular trafficking and the secretion pattern of FSH dramatically enhances ovarian function in mice. Proc Natl Acad Sci U S A (2014) 0.91
Impaired fertility and FSH synthesis in gonadotrope-specific Foxl2 knockout mice. Mol Endocrinol (2013) 0.88
Differential regulation of follicle stimulating hormone by activin A and TGFB1 in murine gonadotropes. Reprod Biol Endocrinol (2005) 0.87
Defective gonadotropin-dependent ovarian folliculogenesis and granulosa cell gene expression in inhibin-deficient mice. Endocrinology (2010) 0.86
Vascularization of the developing chick limb bud: role of the TGFbeta signalling pathway. J Anat (2003) 0.85
Unique mutation portraits and frequent COL2A1 gene alteration in chondrosarcoma. Genome Res (2014) 0.85
Uterine activin receptor-like kinase 5 is crucial for blastocyst implantation and placental development. Proc Natl Acad Sci U S A (2015) 0.84
Bone morphogenetic protein signaling transcription factor (SMAD) function in granulosa cells. Mol Cell Endocrinol (2011) 0.84
Activin/Nodal signalling before implantation: setting the stage for embryo patterning. Philos Trans R Soc Lond B Biol Sci (2014) 0.84
Markers of growth and development in primate primordial follicles are preserved after slow cryopreservation. Fertil Steril (2010) 0.84
Identification of multiple quantitative trait loci affecting the size and shape of the mandible in mice. Mamm Genome (2008) 0.84
Runt-related transcription factors impair activin induction of the follicle-stimulating hormone {beta}-subunit gene. Endocrinology (2010) 0.83
Functional redundancy of type II BMP receptor and type IIB activin receptor in BMP2-induced osteoblast differentiation. J Cell Physiol (2012) 0.83
Nodal·Gdf1 heterodimers with bound prodomains enable serum-independent nodal signaling and endoderm differentiation. J Biol Chem (2014) 0.82
BMP signaling dynamics in embryonic orofacial tissue. J Cell Physiol (2008) 0.81
New insights into ovarian function. Handb Exp Pharmacol (2010) 0.81
Characterization of follistatin-type domains and their contribution to myostatin and activin A antagonism. Mol Endocrinol (2012) 0.81
Bone anabolic agents for the treatment of multiple myeloma. Cancer Microenviron (2011) 0.81
Developmental biology. Angles on activin's absence. Nature (1995) 0.80
Molecular specification of germ layers in vertebrate embryos. Cell Mol Life Sci (2015) 0.80
A truncated, activin-induced Smad3 isoform acts as a transcriptional repressor of FSHβ expression in mouse pituitary. Mol Cell Endocrinol (2011) 0.79
Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development (2015) 0.79
Activin A promotes neuronal differentiation of cerebrocortical neural progenitor cells. PLoS One (2012) 0.79
Fshb-iCre mice are efficient and specific Cre deleters for the gonadotrope lineage. Mol Cell Endocrinol (2015) 0.79
Smad4 overexpression causes germ cell ablation and leydig cell hyperplasia in transgenic mice. Am J Pathol (2002) 0.79
Expression profiling of transforming growth factor beta superfamily genes in developing orofacial tissue. Birth Defects Res A Clin Mol Teratol (2006) 0.79
Molecular basis of cleft palates in mice. World J Biol Chem (2015) 0.78
Testicular cell adhesion molecule 1 (TCAM1) is not essential for fertility. Mol Cell Endocrinol (2009) 0.78
Virtual High-Throughput Screening To Identify Novel Activin Antagonists. J Med Chem (2015) 0.78
Constitutively active FOXO1 diminishes activin induction of Fshb transcription in immortalized gonadotropes. PLoS One (2014) 0.77
Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma. Oncotarget (2015) 0.77
GATA factors in endocrine neoplasia. Mol Cell Endocrinol (2015) 0.77
Transforming Growth Factor β Superfamily Signaling in Development of Colorectal Cancer. Gastroenterology (2016) 0.77
Activin B is produced early in antral follicular development and suppresses thecal androgen production. Reproduction (2012) 0.76
Activin A induces craniofacial cartilage from undifferentiated Xenopus ectoderm in vitro. Proc Natl Acad Sci U S A (2002) 0.76
The TGF-β Family in the Reproductive Tract. Cold Spring Harb Perspect Biol (2017) 0.76
Activin-A co-opts IRF4 and AhR signaling to induce human regulatory T cells that restrain asthmatic responses. Proc Natl Acad Sci U S A (2017) 0.75
Profile of Martin Matzuk. Proc Natl Acad Sci U S A (2016) 0.75
Regulation and 3 dimensional culture of tertiary follicle growth. Clin Exp Reprod Med (2012) 0.75
Towards a cure for Fibrodysplasia ossificans progressiva. Ann Transl Med (2016) 0.75
Overexpression of follistatin in the mouse epididymis disrupts fluid resorption and sperm transit in testicular excurrent ducts. Biol Reprod (2012) 0.75
Activins and their related proteins in colon carcinogenesis: insights from early and advanced azoxymethane rat models of colon cancer. BMC Cancer (2016) 0.75
Activin in acute pancreatitis: Potential risk-stratifying marker and novel therapeutic target. Sci Rep (2017) 0.75
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