Published in EMBO J on August 17, 1998
Focal contacts as mechanosensors: externally applied local mechanical force induces growth of focal contacts by an mDia1-dependent and ROCK-independent mechanism. J Cell Biol (2001) 9.73
Rho GTPases and their effector proteins. Biochem J (2000) 8.89
Sensors and regulators of intracellular pH. Nat Rev Mol Cell Biol (2009) 4.30
Diversity of the mammalian sodium/proton exchanger SLC9 gene family. Pflugers Arch (2003) 2.89
Cell migration requires both ion translocation and cytoskeletal anchoring by the Na-H exchanger NHE1. J Cell Biol (2002) 2.76
Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol (2003) 2.14
Hyaluronan-mediated CD44 activation of RhoGTPase signaling and cytoskeleton function promotes tumor progression. Semin Cancer Biol (2008) 1.91
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Rho kinase in the regulation of cell death and survival. Arch Immunol Ther Exp (Warsz) (2007) 1.60
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Structural and functional analysis of the Na+/H+ exchanger. Biochem J (2007) 1.40
DIP (mDia interacting protein) is a key molecule regulating Rho and Rac in a Src-dependent manner. EMBO J (2004) 1.17
Protein kinase A gating of a pseudopodial-located RhoA/ROCK/p38/NHE1 signal module regulates invasion in breast cancer cell lines. Mol Biol Cell (2005) 1.14
Deficiency of the NHE1 gene prevents hypoxia-induced pulmonary hypertension and vascular remodeling. Am J Respir Crit Care Med (2008) 1.09
The Na+-H+ exchanger-1 induces cytoskeletal changes involving reciprocal RhoA and Rac1 signaling, resulting in motility and invasion in MDA-MB-435 cells. Breast Cancer Res (2004) 1.08
The sodium-hydrogen exchanger NHE1 is an Akt substrate necessary for actin filament reorganization by growth factors. J Biol Chem (2009) 1.05
Regulation of cell survival by Na+/H+ exchanger-1. Am J Physiol Renal Physiol (2008) 1.04
Ca2+ signaling, intracellular pH and cell volume in cell proliferation. J Membr Biol (2005) 0.99
The Na+/H+ exchanger NHE1 in stress-induced signal transduction: implications for cell proliferation and cell death. Pflugers Arch (2006) 0.98
Proton-sensitive cation channels and ion exchangers in ischemic brain injury: new therapeutic targets for stroke? Prog Neurobiol (2014) 0.96
Mislocalized scaffolding by the Na-H exchanger NHE1 dominantly inhibits fibronectin production and TGF-beta activation. Mol Biol Cell (2009) 0.95
The GTP-binding protein RhoA mediates Na,K-ATPase exocytosis in alveolar epithelial cells. Mol Biol Cell (2003) 0.95
Calcineurin B homologous protein 3 promotes the biosynthetic maturation, cell surface stability, and optimal transport of the Na+/H+ exchanger NHE1 isoform. J Biol Chem (2008) 0.95
Nerve growth factor inhibits Na+/H+ exchange and formula absorption through parallel phosphatidylinositol 3-kinase-mTOR and ERK pathways in thick ascending limb. J Biol Chem (2008) 0.93
Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem (2013) 0.89
Endothelin-1 augments Na⁺/H⁺ exchange activity in murine pulmonary arterial smooth muscle cells via Rho kinase. PLoS One (2012) 0.89
Apoptosis-induced alkalinization by the Na+/H+ exchanger isoform 1 is mediated through phosphorylation of amino acids Ser726 and Ser729. Am J Physiol Cell Physiol (2008) 0.83
Mitochondrial NHE1: a newly identified target to prevent heart disease. Front Physiol (2013) 0.82
Bioengineering paradigms for cell migration in confined microenvironments. Curr Opin Cell Biol (2014) 0.82
RhoA Kinase (Rock) and p90 Ribosomal S6 Kinase (p90Rsk) phosphorylation of the sodium hydrogen exchanger (NHE1) is required for lysophosphatidic acid-induced transport, cytoskeletal organization and migration. Cell Signal (2015) 0.81
Na(+)/H(+) exchange and hypoxic pulmonary hypertension. Pulm Circ (2015) 0.80
Na⁺/H⁺ exchangers and intracellular pH in perinatal brain injury. Transl Stroke Res (2014) 0.79
The GPR55 agonist lysophosphatidylinositol relaxes rat mesenteric resistance artery and induces Ca(2+) release in rat mesenteric artery endothelial cells. Br J Pharmacol (2015) 0.78
Na+-H+ exchanger-1 (NHE1) regulation in kidney proximal tubule. Cell Mol Life Sci (2015) 0.77
Role of Rho kinase and Na+/H+ exchange in hypoxia-induced pulmonary arterial smooth muscle cell proliferation and migration. Physiol Rep (2016) 0.77
Role of NHE1 in Nociception. Pain Res Treat (2013) 0.76
Cancer cell motility: lessons from migration in confined spaces. Nat Rev Cancer (2016) 0.76
High-mobility group box 1 inhibits HCO3- absorption in the medullary thick ascending limb through RAGE-Rho-ROCK-mediated inhibition of basolateral Na+/H+ exchange. Am J Physiol Renal Physiol (2016) 0.75
Glial Na(+) -dependent ion transporters in pathophysiological conditions. Glia (2016) 0.75
Uni-axial stretch induces actin stress fiber reorganization and activates c-Jun NH2 terminal kinase via RhoA and Rho kinase in human bladder smooth muscle cells. BMC Urol (2016) 0.75
The cleaved FAS ligand activates the Na(+)/H(+) exchanger NHE1 through Akt/ROCK1 to stimulate cell motility. Sci Rep (2016) 0.75
A Histidine Cluster in the Cytoplasmic Domain of the Na-H Exchanger NHE1 Confers pH-sensitive Phospholipid Binding and Regulates Transporter Activity. J Biol Chem (2016) 0.75
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The carboxyl-terminal region of the Na+/H+ exchanger interacts with mammalian heat shock protein. Biochemistry (1995) 1.17
Modulation of band 3-ankyrin interaction by protein 4.1. Functional implications in regulation of erythrocyte membrane mechanical properties. J Biol Chem (1996) 1.16
Induction of tyrosine phosphorylation and Na+/H+ exchanger activation during shrinkage of human neutrophils. J Biol Chem (1997) 1.14
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The links between cellular Ca2+ and Na+/H+ exchange in the pathophysiology of essential hypertension. Am J Hypertens (1996) 0.78
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Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science (1999) 7.12
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