Published in BMC Genet on May 19, 2005
A high-throughput method for quantifying alleles and haplotypes of the malaria vaccine candidate Plasmodium falciparum merozoite surface protein-1 19 kDa. Malar J (2006) 1.41
A survey on haplotyping algorithms for tightly linked markers. J Bioinform Comput Biol (2008) 1.06
Impact of genotyping errors on the type I error rate and the power of haplotype-based association methods. BMC Genet (2009) 0.85
Genotyping error detection in samples of unrelated individuals without replicate genotyping. Hum Hered (2008) 0.82
Estimating the single nucleotide polymorphism genotype misclassification from routine double measurements in a large epidemiologic sample. Am J Epidemiol (2008) 0.81
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A physical map of 30,000 human genes. Science (1998) 12.43
Accuracy of haplotype frequency estimation for biallelic loci, via the expectation-maximization algorithm for unphased diploid genotype data. Am J Hum Genet (2000) 11.47
DNA Pooling: a tool for large-scale association studies. Nat Rev Genet (2002) 5.66
Accessing genetic variation: genotyping single nucleotide polymorphisms. Nat Rev Genet (2001) 5.00
Power and sample size calculations for case-control genetic association tests when errors are present: application to single nucleotide polymorphisms. Hum Hered (2002) 2.74
The impact of genotyping error on haplotype reconstruction and frequency estimation. Eur J Hum Genet (2002) 2.51
Probability of detection of genotyping errors and mutations as inheritance inconsistencies in nuclear-family data. Am J Hum Genet (2002) 2.15
SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis. Nucleic Acids Res (2002) 2.12
Universal, robust, highly quantitative SNP allele frequency measurement in DNA pools. Hum Genet (2002) 2.03
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Determining SNP allele frequencies in DNA pools. Biotechniques (2000) 1.46
Estimation of haplotype frequencies, linkage-disequilibrium measures, and combination of haplotype copies in each pool by use of pooled DNA data. Am J Hum Genet (2003) 1.42
On the use of DNA pooling to estimate haplotype frequencies. Genet Epidemiol (2003) 1.33
Haplotype frequency estimation in the presence of genotyping errors. Hum Hered (2003) 0.86
SNP analysis to dissect human traits. Curr Opin Neurobiol (2001) 0.86
Optimal two-stage genotyping in population-based association studies. Genet Epidemiol (2003) 6.01
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Improved power by use of a weighted score test for linkage disequilibrium mapping. Am J Hum Genet (2006) 3.36
Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered (2003) 3.33
Choosing an optimal method to combine P-values. Stat Med (2009) 3.15
The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol (2007) 3.01
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet (2003) 2.92
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet (2005) 2.80
Cost-effectiveness analysis of screening for KRAS and BRAF mutations in metastatic colorectal cancer. J Natl Cancer Inst (2012) 2.52
Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet (2004) 2.36
Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet (2004) 2.21
Risk of heart failure in breast cancer patients after anthracycline and trastuzumab treatment: a retrospective cohort study. J Natl Cancer Inst (2012) 2.21
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. Am J Hum Genet (2008) 2.20
Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet (2005) 2.18
A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Stat Med (2006) 2.18
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (2006) 2.08
Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am J Respir Crit Care Med (2004) 2.03
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. J Diabetes Complications (2005) 1.87
Self-reported race and genetic admixture. N Engl J Med (2006) 1.85
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A (2003) 1.84
The meaning of interaction. Hum Hered (2010) 1.83
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
A whole-genome scan for obstructive sleep apnea and obesity. Am J Hum Genet (2002) 1.81
Awareness and utilization of BRCA1/2 testing among U.S. primary care physicians. Am J Prev Med (2011) 1.80
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes (2007) 1.61
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet (2007) 1.55
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet (2003) 1.53
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (2007) 1.44
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol (2002) 1.44
Sampling correction in linkage analysis. Genet Epidemiol (2004) 1.43
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol (2011) 1.43
Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One (2008) 1.41
Plasma aldosterone is independently associated with the metabolic syndrome. Hypertension (2006) 1.40
Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association. Hum Hered (2007) 1.39
Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res (2009) 1.38
Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am J Hum Genet (2004) 1.36
Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. Hum Mol Genet (2005) 1.36
Stakeholder assessment of the evidence for cancer genomic tests: insights from three case studies. Genet Med (2012) 1.32
A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans. Am J Hum Genet (2006) 1.31
Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci (2008) 1.29
Statistical interaction in human genetics: how should we model it if we are looking for biological interaction? Nat Rev Genet (2010) 1.28
Two-level Haseman-Elston regression for general pedigree data analysis. Genet Epidemiol (2005) 1.28
Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study. Proc Natl Acad Sci U S A (2004) 1.27
Identification of Barrett's esophagus in relatives by endoscopic screening. Am J Gastroenterol (2004) 1.26
The power of independent types of genetic information to detect association in a case-control study design. Genet Epidemiol (2008) 1.24
CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt. Hypertension (2007) 1.23
Adaptive two-stage analysis of genetic association in case-control designs. Hum Hered (2007) 1.23
Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population. Physiol Genomics (2005) 1.22
Single-marker and two-marker association tests for unphased case-control genotype data, with a power comparison. Genet Epidemiol (2010) 1.22
A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotyped. Genet Epidemiol (2009) 1.18
A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study. Sarcoidosis Vasc Diffuse Lung Dis (2005) 1.18
Two-marker association tests yield new disease associations for coronary artery disease and hypertension. Hum Genet (2011) 1.16
Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m. Proc Natl Acad Sci U S A (2004) 1.16
Heritability analysis of cytokines as intermediate phenotypes of tuberculosis. J Infect Dis (2003) 1.16
Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Hum Hered (2003) 1.15
Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence. Biol Psychiatry (2008) 1.13
Heritability of renal function in hypertensive families of African descent in the Seychelles (Indian Ocean). Kidney Int (2005) 1.13
Detecting genetic interactions for quantitative traits with U-statistics. Genet Epidemiol (2011) 1.13
The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity. Am J Hum Genet (2003) 1.11
Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. Am J Hum Genet (2008) 1.10
Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure. BMC Genet (2003) 1.10
In silico gene prioritization by integrating multiple data sources. PLoS One (2011) 1.10
GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks. AIDS (2004) 1.08
Robust asymptotic sampling theory for correlations in pedigrees. Stat Med (2003) 1.07
Haplotype-based quantitative trait mapping using a clustering algorithm. BMC Bioinformatics (2006) 1.07
Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. Am J Nephrol (2011) 1.07
Genetic ancestry and income are associated with dengue hemorrhagic fever in a highly admixed population. Eur J Hum Genet (2008) 1.07
Genetic analysis of polymorphisms in biologically relevant candidate genes in patients with abdominal aortic aneurysms. J Vasc Surg (2005) 1.07
A second locus for very-late-onset Alzheimer disease: a genome scan reveals linkage to 20p and epistasis between 20p and the amyloid precursor protein region. Am J Hum Genet (2002) 1.07
Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans. Biol Psychiatry (2006) 1.05
Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis. Hum Hered (2005) 1.05
Association of vitamin D receptor gene variants, adiposity and colon cancer. Carcinogenesis (2008) 1.05
Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes. Hum Genet (2007) 1.04
Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes. Hum Mol Genet (2007) 1.03
The distribution of long range admixture linkage disequilibrium in an African-American population. Hum Hered (2002) 1.03
A modified revisited Haseman-Elston method to further improve power. Hum Hered (2004) 1.02
A framework for structural equation models in general pedigrees. Hum Hered (2011) 1.02
Structural equation model-based genome scan for the metabolic syndrome. BMC Genet (2003) 1.02
High heritability of ambulatory blood pressure in families of East African descent. Hypertension (2005) 1.02
Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs. Ann Hum Genet (2005) 1.01
A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology. Int J Epidemiol (2007) 1.01
A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. Genet Epidemiol (2012) 1.00
Identification of gene-gene interactions in the presence of missing data using the multifactor dimensionality reduction method. Genet Epidemiol (2009) 1.00
The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium. Am J Hum Genet (2006) 1.00
KRAS testing and epidermal growth factor receptor inhibitor treatment for colorectal cancer in community settings. Cancer Epidemiol Biomarkers Prev (2012) 1.00
Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data. BMC Syst Biol (2012) 1.00
Evaluation of removable statistical interaction for binary traits. Stat Med (2012) 0.99
Comparative effectiveness research in cancer genomics and precision medicine: current landscape and future prospects. J Natl Cancer Inst (2013) 0.98
Distribution and magnitude of type I error of model-based multipoint lod scores: implications for multipoint mod scores. Genet Epidemiol (2006) 0.98
Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2. Hum Immunol (2008) 0.97