Published in Am J Hum Genet on March 09, 2005
Cholinergic nicotinic receptor genes implicated in a nicotine dependence association study targeting 348 candidate genes with 3713 SNPs. Hum Mol Genet (2006) 13.16
Novel genes identified in a high-density genome wide association study for nicotine dependence. Hum Mol Genet (2006) 7.90
Alpha-5/alpha-3 nicotinic receptor subunit alleles increase risk for heavy smoking. Mol Psychiatry (2008) 6.37
Identifying susceptibility loci for nicotine dependence: 2008 update based on recent genome-wide linkage analyses. Hum Genet (2008) 1.94
Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking. Addiction (2008) 1.91
New insights into the genetics of addiction. Nat Rev Genet (2009) 1.70
Nicotine response genetics in the zebrafish. Proc Natl Acad Sci U S A (2009) 1.45
Oral clefts and life style factors--a case-cohort study based on prospective Danish data. Eur J Epidemiol (2007) 1.33
A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans. Am J Hum Genet (2006) 1.31
Genetics of nicotine dependence and pharmacotherapy. Biochem Pharmacol (2007) 1.21
Convergent evidence that choline acetyltransferase gene variation is associated with prospective smoking cessation and nicotine dependence. Neuropsychopharmacology (2010) 1.17
Genome-wide association analyses suggested a novel mechanism for smoking behavior regulated by IL15. Mol Psychiatry (2009) 1.09
Genome wide association for addiction: replicated results and comparisons of two analytic approaches. PLoS One (2010) 1.04
Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology (2009) 1.04
Common and unique biological pathways associated with smoking initiation/progression, nicotine dependence, and smoking cessation. Neuropsychopharmacology (2009) 1.03
Cannabinoid receptor 1 gene association with nicotine dependence. Arch Gen Psychiatry (2008) 1.01
Association and interaction analyses of GABBR1 and GABBR2 with nicotine dependence in European- and African-American populations. PLoS One (2009) 1.00
GENES AS INSTRUMENTS FOR STUDYING RISK BEHAVIOR EFFECTS: AN APPLICATION TO MATERNAL SMOKING AND OROFACIAL CLEFTS. Health Serv Outcomes Res Methodol (2011) 0.98
Susceptibility locus in neurokinin-1 receptor gene associated with alcohol dependence. Neuropsychopharmacology (2009) 0.94
Symbiotic relationship of pharmacogenetics and drugs of abuse. AAPS J (2006) 0.93
Transcriptome sequencing of gene expression in the brain of the HIV-1 transgenic rat. PLoS One (2013) 0.91
The role of 5-HT3 receptors in drug abuse and as a target for pharmacotherapy. CNS Neurol Disord Drug Targets (2008) 0.91
The Role of the Habenula in Nicotine Addiction. J Addict Res Ther (2011) 0.90
Smoking and body weight: evidence using genetic instruments. Econ Hum Biol (2011) 0.88
Genetics of GABAergic signaling in nicotine and alcohol dependence. Hum Genet (2011) 0.87
Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers. Drug Alcohol Depend (2013) 0.84
Significant associations of CHRNA2 and CHRNA6 with nicotine dependence in European American and African American populations. Hum Genet (2013) 0.83
The contribution of rare and common variants in 30 genes to risk nicotine dependence. Mol Psychiatry (2014) 0.82
A genetic instrumental variables analysis of the effects of prenatal smoking on birth weight: evidence from two samples. Biodemography Soc Biol (2011) 0.82
Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerström Test for Nicotine Dependence. Addiction (2009) 0.79
Gene network analysis shows immune-signaling and ERK1/2 as novel genetic markers for multiple addiction phenotypes: alcohol, smoking and opioid addiction. BMC Syst Biol (2015) 0.78
New mechanisms and perspectives in nicotine withdrawal. Neuropharmacology (2014) 0.77
Intergenerational continuity in parents' and adolescents' externalizing problems: The role of life events and their interaction with GABRA2. J Abnorm Psychol (2015) 0.76
Assessing the impact of nicotine dependence genes on the risk of facial clefts: An example of the use of national registry and biobank data. Nor Epidemiol (2015) 0.76
Converging findings from linkage and association analyses on susceptibility genes for smoking and other addictions. Mol Psychiatry (2016) 0.75
Targeted sequencing identifies genetic polymorphisms of flavin-containing monooxygenase genes contributing to susceptibility of nicotine dependence in European American and African American. Brain Behav (2017) 0.75
Genetic research on nicotine dependence will facilitate public health. PLoS Med (2005) 0.75
Ethnic-specific genetic association of variants in the corticotropin-releasing hormone receptor 1 gene with nicotine dependence. Biomed Res Int (2015) 0.75
GABA Receptors Genes Polymorphisms and Alcohol Dependence: No Evidence of an Association in an Italian Male Population. Clin Psychopharmacol Neurosci (2014) 0.75
The Impact of Cigarette Quitting during Pregnancy on Other Prenatal Health Behaviors. Rev Econ Househ (2013) 0.75
Detecting Gene-Gene Interactions Associated with Multiple Complex Traits with U-Statistics. Curr Genomics (2016) 0.75
The Fagerström Test for Nicotine Dependence: a revision of the Fagerström Tolerance Questionnaire. Br J Addict (1991) 63.91
PedCheck: a program for identification of genotype incompatibilities in linkage analysis. Am J Hum Genet (1998) 23.25
A simple correction for multiple testing for single-nucleotide polymorphisms in linkage disequilibrium with each other. Am J Hum Genet (2004) 14.76
GOLD--graphical overview of linkage disequilibrium. Bioinformatics (2000) 9.43
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics. Genet Epidemiol (2004) 5.57
GABA(B) receptors function as a heteromeric assembly of the subunits GABA(B)R1 and GABA(B)R2. Nature (1998) 5.03
Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations. Am J Hum Genet (2004) 5.02
A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
GABA(B)-receptor subtypes assemble into functional heteromeric complexes. Nature (1998) 4.33
A multivariate family-based association test using generalized estimating equations: FBAT-GEE. Biostatistics (2003) 3.52
The genetic epidemiology of smoking. Nicotine Tob Res (1999) 3.21
Epilepsy, hyperalgesia, impaired memory, and loss of pre- and postsynaptic GABA(B) responses in mice lacking GABA(B(1)). Neuron (2001) 2.51
The genetics of smoking persistence in men and women: a multicultural study. Behav Genet (1999) 2.11
A genomic scan for habitual smoking in families of alcoholics: common and specific genetic factors in substance dependence. Am J Med Genet A (2004) 1.88
Results of a genomewide linkage scan: support for chromosomes 9 and 11 loci increasing risk for cigarette smoking. Am J Med Genet B Neuropsychiatr Genet (2004) 1.67
Genetics of alcohol and tobacco use in humans. Ann Med (2003) 1.62
A genome-wide search for loci contributing to smoking and alcoholism. Genet Epidemiol (1999) 1.55
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
A pharmacologic strategy for the treatment of nicotine addiction. Synapse (1999) 1.27
Substance abuse vulnerability loci: converging genome scanning data. Trends Genet (2002) 1.26
Progress in searching for susceptibility loci and genes for smoking-related behaviour. Clin Genet (2004) 1.24
Effects of a single dose of baclofen on self-reported subjective effects and tobacco smoking. Nicotine Tob Res (2001) 1.16
Baclofen antagonizes intravenous self-administration of nicotine in mice and rats. Alcohol Alcohol (2002) 1.16
Response of nicotine self-administration in the rat to manipulations of mu-opioid and gamma-aminobutyric acid receptors in the ventral tegmental area. Psychopharmacology (Berl) (2000) 1.16
Genetic and social determinants of initiation and age at onset of smoking in Australian twins. Behav Genet (1999) 1.10
Human GABA(B)R genomic structure: evidence for splice variants in GABA(B)R1 but not GABA(B)R2. Gene (2001) 1.04
A placebo-controlled trial of pioglitazone in subjects with nonalcoholic steatohepatitis. N Engl J Med (2006) 10.97
Optimal two-stage genotyping in population-based association studies. Genet Epidemiol (2003) 6.01
Oral topiramate for treatment of alcohol dependence: a randomised controlled trial. Lancet (2003) 4.79
A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet (2007) 4.46
A meta-analysis of estimated genetic and environmental effects on smoking behavior in male and female adult twins. Addiction (2003) 4.37
Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD. PLoS Genet (2010) 3.91
Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A (2010) 3.78
Improved power by use of a weighted score test for linkage disequilibrium mapping. Am J Hum Genet (2006) 3.36
Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered (2003) 3.33
Choosing an optimal method to combine P-values. Stat Med (2009) 3.15
The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol (2007) 3.01
A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet (2008) 3.00
Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet (2003) 2.92
Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol (2010) 2.80
Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet (2005) 2.80
Blood pressure and mortality in U.S. veterans with chronic kidney disease: a cohort study. Ann Intern Med (2013) 2.74
Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet (2004) 2.36
Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet (2004) 2.21
Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. Am J Hum Genet (2008) 2.20
A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Stat Med (2006) 2.18
Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics (2006) 2.08
Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am J Respir Crit Care Med (2004) 2.03
Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetes. Circulation (2002) 1.91
Outcomes associated with microalbuminuria: effect modification by chronic kidney disease. J Am Coll Cardiol (2013) 1.89
Preoperative statin administration is associated with lower mortality and decreased need for postoperative hemodialysis in patients undergoing coronary artery bypass graft surgery. J Cardiothorac Vasc Anesth (2009) 1.88
The associations between race and geographic area and quality-of-care indicators in patients approaching ESRD. Clin J Am Soc Nephrol (2013) 1.87
The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. J Diabetes Complications (2005) 1.87
Hyponatremia, hypernatremia, and mortality in patients with chronic kidney disease with and without congestive heart failure. Circulation (2012) 1.86
Self-reported race and genetic admixture. N Engl J Med (2006) 1.85
A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A (2003) 1.84
The meaning of interaction. Hum Hered (2010) 1.83
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet (2009) 1.82
A whole-genome scan for obstructive sleep apnea and obesity. Am J Hum Genet (2002) 1.81
Influence of comorbid conditions on long-term mortality after pneumonia in older people. J Am Geriatr Soc (2007) 1.79
Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes (2007) 1.79
Pharmacogenetic approach at the serotonin transporter gene as a method of reducing the severity of alcohol drinking. Am J Psychiatry (2011) 1.69
Long-term survival of dialysis patients in the United States with prosthetic heart valves: should ACC/AHA practice guidelines on valve selection be modified? Circulation (2002) 1.63
Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes (2007) 1.61
Topiramate for the treatment of methamphetamine addiction: a multi-center placebo-controlled trial. Addiction (2012) 1.59
A survey of oral and maxillofacial surgeons' tobacco-use-related knowledge, attitudes and intervention behaviors. J Am Dent Assoc (2008) 1.58
Interleukin-1 receptor antagonist intron 2 variable number of tandem repeats polymorphism and respiratory failure in children with community-acquired pneumonia. Pediatr Crit Care Med (2008) 1.57
A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet (2008) 1.57
Significant association of BDNF haplotypes in European-American male smokers but not in European-American female or African-American smokers. Am J Med Genet B Neuropsychiatr Genet (2005) 1.55
Trial design: The St. Jude Children's Research Hospital Cancer Survivors Tobacco Quit Line study. Contemp Clin Trials (2009) 1.55
Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet (2007) 1.55
A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet (2003) 1.53
A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet (2003) 1.50
Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans. Am J Med Genet B Neuropsychiatr Genet (2010) 1.48
Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics (2007) 1.44
Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol (2002) 1.44
Sampling correction in linkage analysis. Genet Epidemiol (2004) 1.43
Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol (2011) 1.43
Genetic research and smoking behavior. JAMA (2007) 1.42
Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One (2008) 1.41
Plasma aldosterone is independently associated with the metabolic syndrome. Hypertension (2006) 1.40
The 5A's vs 3A's plus proactive quitline referral in private practice dental offices: preliminary results. Tob Control (2007) 1.40
Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association. Hum Hered (2007) 1.39
Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res (2009) 1.38
Differential allelic expression of dopamine D1 receptor gene (DRD1) is modulated by microRNA miR-504. Biol Psychiatry (2009) 1.37
Significant association of catechol-O-methyltransferase (COMT) haplotypes with nicotine dependence in male and female smokers of two ethnic populations. Neuropsychopharmacology (2006) 1.36
Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am J Hum Genet (2004) 1.36
Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. Hum Mol Genet (2005) 1.36
Smoking and genetic risk variation across populations of European, Asian, and African American ancestry--a meta-analysis of chromosome 15q25. Genet Epidemiol (2012) 1.34
Significant association of DRD1 with nicotine dependence. Hum Genet (2007) 1.33
The relationship of age, race, and ethnicity with survival in dialysis patients. Clin J Am Soc Nephrol (2013) 1.32
Significant association of ANKK1 and detection of a functional polymorphism with nicotine dependence in an African-American sample. Neuropsychopharmacology (2008) 1.31