Published in Nat Struct Mol Biol on November 05, 2007
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Integrated genome-wide chromatin occupancy and expression analyses identify key myeloid pro-differentiation transcription factors repressed by Myb. Nucleic Acids Res (2011) 1.13
Compensatory functions of histone deacetylase 1 (HDAC1) and HDAC2 regulate transcription and apoptosis during mouse oocyte development. Proc Natl Acad Sci U S A (2012) 1.12
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Deficiency of H3K79 histone methyltransferase Dot1-like protein (DOT1L) inhibits cell proliferation. J Biol Chem (2011) 1.04
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Inhibition of histone H3K79 methylation selectively inhibits proliferation, self-renewal and metastatic potential of breast cancer. Oncotarget (2014) 1.03
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IDEAL in 2014 illustrates interaction networks composed of intrinsically disordered proteins and their binding partners. Nucleic Acids Res (2013) 0.98
Epigenetic factors and cardiac development. Cardiovasc Res (2011) 0.97
Efficient cell migration requires global chromatin condensation. J Cell Sci (2010) 0.97
Histone variants and their post-translational modifications in primary human fat cells. PLoS One (2011) 0.97
Histone methylase MLL1 has critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo. Oncogene (2012) 0.96
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. Mol Biosyst (2011) 0.96
A medicinal chemistry perspective for targeting histone H3 lysine-79 methyltransferase DOT1L. J Med Chem (2013) 0.95
Histone arginine methylations: their roles in chromatin dynamics and transcriptional regulation. Biosci Rep (2009) 0.95
Assay development for histone methyltransferases. Assay Drug Dev Technol (2013) 0.94
MRG15, a component of HAT and HDAC complexes, is essential for proliferation and differentiation of neural precursor cells. J Neurosci Res (2009) 0.94
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The histone H3K36 demethylase Rph1/KDM4 regulates the expression of the photoreactivation gene PHR1. Nucleic Acids Res (2011) 0.93
MicroRNAs and epigenetic regulation in the mammalian inner ear: implications for deafness. Mamm Genome (2009) 0.93
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How the epigenome contributes to the development of psychiatric disorders. Dev Psychobiol (2010) 0.92
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Histone deacetylase inhibitors as novel anticancer therapeutics. Curr Oncol (2008) 0.92
Developmental regulation of N-terminal H2B methylation in Drosophila melanogaster. Nucleic Acids Res (2011) 0.92
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New nomenclature for chromatin-modifying enzymes. Cell (2007) 5.34
Histone H2B monoubiquitination functions cooperatively with FACT to regulate elongation by RNA polymerase II. Cell (2006) 5.14
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AFF4, a component of the ELL/P-TEFb elongation complex and a shared subunit of MLL chimeras, can link transcription elongation to leukemia. Mol Cell (2010) 4.99
Methylation of histone H3 by COMPASS requires ubiquitination of histone H2B by Rad6. J Biol Chem (2002) 4.75
Bre1, an E3 ubiquitin ligase required for recruitment and substrate selection of Rad6 at a promoter. Mol Cell (2003) 4.49
Histone crosstalk between H2B monoubiquitination and H3 methylation mediated by COMPASS. Cell (2007) 4.49
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Human mediator subunit MED26 functions as a docking site for transcription elongation factors. Cell (2011) 2.53
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The trithorax-group gene in Drosophila little imaginal discs encodes a trimethylated histone H3 Lys4 demethylase. Nat Struct Mol Biol (2007) 2.05
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The COMPASS family of H3K4 methylases in Drosophila. Mol Cell Biol (2011) 1.54
Drosophila Rtf1 functions in histone methylation, gene expression, and Notch signaling. Proc Natl Acad Sci U S A (2006) 1.54
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Ctk complex-mediated regulation of histone methylation by COMPASS. Mol Cell Biol (2006) 1.50
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Cdk9 is an essential kinase in Drosophila that is required for heat shock gene expression, histone methylation and elongation factor recruitment. Mol Genet Genomics (2006) 1.42
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The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation. Cell (2012) 1.33
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Structural analysis of the core COMPASS family of histone H3K4 methylases from yeast to human. Proc Natl Acad Sci U S A (2011) 1.12
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Global proteomic analysis of S. cerevisiae (GPS) to identify proteins required for histone modifications. Methods Enzymol (2004) 1.07
The little elongation complex regulates small nuclear RNA transcription. Mol Cell (2011) 1.06
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MQX-503, a novel formulation of nitroglycerin, improves the severity of Raynaud's phenomenon: a randomized, controlled trial. Arthritis Rheum (2009) 1.03
Increased levels of transforming growth factor beta receptor type I and up-regulation of matrix gene program: A model of scleroderma. Arthritis Rheum (2006) 1.02
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In vivo requirement of the RNA polymerase II elongation factor elongin A for proper gene expression and development. Mol Cell Biol (2004) 1.01
Transcriptional elongation checkpoint control in development and disease. Genes Dev (2013) 0.98
SnapShot: Histone lysine methylase complexes. Cell (2012) 0.92
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Mutational analysis of an RNA polymerase II elongation factor in Drosophila melanogaster. Mol Cell Biol (2005) 0.90
Developmental biology. Histone cross-talk in stem cells. Science (2009) 0.88
The curious case of bivalent marks. Dev Cell (2009) 0.87
Drosophila SETs its sights on cancer: Trr/MLL3/4 COMPASS-like complexes in development and disease. Mol Cell Biol (2013) 0.87
Impact of interactions of cigarette smoking with NAT2 polymorphisms on rheumatoid arthritis risk in African Americans. Arthritis Rheum (2012) 0.87
The little elongation complex functions at initiation and elongation phases of snRNA gene transcription. Mol Cell (2013) 0.86
Histone demethylase dUTX antagonizes JAK-STAT signaling to maintain proper gene expression and architecture of the Drosophila testis niche. Development (2013) 0.86