The ubiquitin binding region of the Smurf HECT domain facilitates polyubiquitylation and binding of ubiquitylated substrates.

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Published in J Biol Chem on December 21, 2009

Authors

Abiodun A Ogunjimi1, Silke Wiesner, Douglas J Briant, Xaralabos Varelas, Frank Sicheri, Julie Forman-Kay, Jeffrey L Wrana

Author Affiliations

1: Center for Systems Biology, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario M5G 1X5, Canada.

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