MicroRNA control of signal transduction.

MicroRNA functions in stress responses. Mol Cell (2010) 4.46

The 'ins' and 'outs' of podosomes and invadopodia: characteristics, formation and function. Nat Rev Mol Cell Biol (2011) 4.24

Cellular and molecular mechanisms of renal fibrosis. Nat Rev Nephrol (2011) 3.68

RNA-ligase-dependent biases in miRNA representation in deep-sequenced small RNA cDNA libraries. RNA (2011) 3.00

The Notch signalling system: recent insights into the complexity of a conserved pathway. Nat Rev Genet (2012) 2.77

MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth factor receptor-1. Arterioscler Thromb Vasc Biol (2011) 2.31

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells. Kidney Int (2011) 2.30

The microRNA miR-181 is a critical cellular metabolic rheostat essential for NKT cell ontogenesis and lymphocyte development and homeostasis. Immunity (2013) 2.13

ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data. Nucleic Acids Res (2012) 2.11

Interactions of miR-323/miR-326/miR-329 and miR-130a/miR-155/miR-210 as prognostic indicators for clinical outcome of glioblastoma patients. J Transl Med (2013) 2.04

Focal segmental glomerulosclerosis is induced by microRNA-193a and its downregulation of WT1. Nat Med (2013) 1.98

Regulating the regulators: the pervasive effects of Pol II pausing on stimulus-responsive gene networks. Genes Dev (2012) 1.91

MicroRNAs in resolution of acute inflammation: identification of novel resolvin D1-miRNA circuits. FASEB J (2010) 1.87

microRNA-1/133a and microRNA-206/133b clusters: dysregulation and functional roles in human cancers. Oncotarget (2012) 1.83

miR-27b controls venous specification and tip cell fate. Blood (2011) 1.79

Context-dependent functions of specific microRNAs in neuronal development. Neural Dev (2010) 1.74

Aberrant expression of microRNAs in bladder cancer. Nat Rev Urol (2013) 1.74

miRNA expression in colon polyps provides evidence for a multihit model of colon cancer. PLoS One (2011) 1.72

Inhibiting microRNA-192 ameliorates renal fibrosis in diabetic nephropathy. J Am Soc Nephrol (2012) 1.70

Global microRNA level regulation of EGFR-driven cell-cycle protein network in breast cancer. Mol Syst Biol (2012) 1.69

Nanopore-based detection of circulating microRNAs in lung cancer patients. Nat Nanotechnol (2011) 1.68

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy. J Biol Chem (2011) 1.68

MicroRNA-155 targets SMAD2 and modulates the response of macrophages to transforming growth factor-{beta}. J Biol Chem (2010) 1.67

miR-194 is a marker of hepatic epithelial cells and suppresses metastasis of liver cancer cells in mice. Hepatology (2010) 1.66

microRNA-214 contributes to melanoma tumour progression through suppression of TFAP2C. EMBO J (2011) 1.66

Cancer chemoprevention by dietary polyphenols: promising role for epigenetics. Biochem Pharmacol (2010) 1.63

miR-29 inhibits bleomycin-induced pulmonary fibrosis in mice. Mol Ther (2012) 1.56

Conserved regulation of p53 network dosage by microRNA-125b occurs through evolving miRNA-target gene pairs. PLoS Genet (2011) 1.55

Therapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorder. Pharmacol Rev (2013) 1.52

Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study. BMJ Open (2012) 1.50

Role of Notch and its oncogenic signaling crosstalk in breast cancer. Biochim Biophys Acta (2010) 1.50

Targeting epigenetic regulation of miR-34a for treatment of pancreatic cancer by inhibition of pancreatic cancer stem cells. PLoS One (2011) 1.48

The biological functions of miRNAs: lessons from in vivo studies. Trends Cell Biol (2014) 1.47

Reactive oxygen species in cancer stem cells. Antioxid Redox Signal (2012) 1.44

miR-1-mediated induction of cardiogenesis in mesenchymal stem cells via downregulation of Hes-1. Biomed Res Int (2012) 1.44

Post-transcriptional up-regulation of Tsc-22 by Ybx1, a target of miR-216a, mediates TGF-{beta}-induced collagen expression in kidney cells. J Biol Chem (2010) 1.42

Airway epithelial miRNA expression is altered in asthma. Am J Respir Crit Care Med (2012) 1.42

The microRNA body map: dissecting microRNA function through integrative genomics. Nucleic Acids Res (2011) 1.41

Tumor suppressor p53 meets microRNAs. J Mol Cell Biol (2011) 1.39

Circulating miR-125b is a novel biomarker for screening non-small-cell lung cancer and predicts poor prognosis. J Cancer Res Clin Oncol (2012) 1.38

Identification of Molecular Markers of Delayed Graft Function Based on the Regulation of Biological Ageing. PLoS One (2016) 1.38

Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. PLoS One (2016) 1.37

Barcoded cDNA library preparation for small RNA profiling by next-generation sequencing. Methods (2012) 1.37

Expression of miRNA-106b in conventional renal cell carcinoma is a potential marker for prediction of early metastasis after nephrectomy. J Exp Clin Cancer Res (2010) 1.36

Oncogenic miRNA-182-5p targets Smad4 and RECK in human bladder cancer. PLoS One (2012) 1.35

MAGIA²: from miRNA and genes expression data integrative analysis to microRNA-transcription factor mixed regulatory circuits (2012 update). Nucleic Acids Res (2012) 1.27

MicroRNA-182-5p promotes cell invasion and proliferation by down regulating FOXF2, RECK and MTSS1 genes in human prostate cancer. PLoS One (2013) 1.27

Cigarette smoke induces C/EBP-β-mediated activation of miR-31 in normal human respiratory epithelia and lung cancer cells. PLoS One (2010) 1.27

microRNA-Seq reveals cocaine-regulated expression of striatal microRNAs. RNA (2011) 1.26

Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos Trans R Soc Lond B Biol Sci (2013) 1.26

MIR-210 modulates mitochondrial respiration in placenta with preeclampsia. Placenta (2012) 1.26

Repertoire of porcine microRNAs in adult ovary and testis by deep sequencing. Int J Biol Sci (2011) 1.22

MicroRNA down-regulated in human cholangiocarcinoma control cell cycle through multiple targets involved in the G1/S checkpoint. Hepatology (2011) 1.22

miRNA-transcription factor interactions: a combinatorial regulation of gene expression. Mol Genet Genomics (2013) 1.21

Post-translational regulation of TGF-β receptor and Smad signaling. FEBS Lett (2012) 1.21

Modelling Competing Endogenous RNA Networks. PLoS One (2013) 1.21

MicroRNA regulatory networks in human adipose tissue and obesity. Nat Rev Endocrinol (2015) 1.20

miR-7a regulation of Pax6 controls spatial origin of forebrain dopaminergic neurons. Nat Neurosci (2012) 1.19

Vitamin D receptor signaling mechanisms: integrated actions of a well-defined transcription factor. Steroids (2012) 1.18

MicroRNA-1826 targets VEGFC, beta-catenin (CTNNB1) and MEK1 (MAP2K1) in human bladder cancer. Carcinogenesis (2011) 1.16

Good guy or bad guy: the opposing roles of microRNA 125b in cancer. Cell Commun Signal (2014) 1.15

Biological robustness and the role of microRNAs: a network perspective. Curr Top Dev Biol (2012) 1.14

The microRNA -23b/-27b cluster suppresses the metastatic phenotype of castration-resistant prostate cancer cells. PLoS One (2012) 1.14

Role of MicroRNAs in Fibrosis. Open Rheumatol J (2012) 1.14

Identification of MicroRNAs involved in hypoxia- and serum deprivation-induced apoptosis in mesenchymal stem cells. Int J Biol Sci (2011) 1.13

Insulin-like growth factor-1 receptor is regulated by microRNA-133 during skeletal myogenesis. PLoS One (2011) 1.13

In vivo NCL targeting affects breast cancer aggressiveness through miRNA regulation. J Exp Med (2013) 1.13

EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours. Sci Rep (2012) 1.10

Neuronal exosomal miRNA-dependent translational regulation of astroglial glutamate transporter GLT1. J Biol Chem (2013) 1.10

Loss of the miR-144/451 cluster impairs ischaemic preconditioning-mediated cardioprotection by targeting Rac-1. Cardiovasc Res (2012) 1.09

Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma. Cell Cycle (2012) 1.08

miR-145 functions as tumor suppressor and targets two oncogenes, ANGPT2 and NEDD9, in renal cell carcinoma. J Cancer Res Clin Oncol (2014) 1.07

Contact inhibition modulates intracellular levels of miR-223 in a p27kip1-dependent manner. Oncotarget (2014) 1.07

MicroRNAs--novel regulators of systemic lupus erythematosus pathogenesis. Nat Rev Rheumatol (2012) 1.06

miTALOS: analyzing the tissue-specific regulation of signaling pathways by human and mouse microRNAs. RNA (2011) 1.05

Modification of gene duplicability during the evolution of protein interaction network. PLoS Comput Biol (2011) 1.05

Discovery of novel human breast cancer microRNAs from deep sequencing data by analysis of pri-microRNA secondary structures. PLoS One (2011) 1.05

miR-200c sensitizes breast cancer cells to doxorubicin treatment by decreasing TrkB and Bmi1 expression. PLoS One (2012) 1.05

miR-19a: an effective regulator of SOCS3 and enhancer of JAK-STAT signalling. PLoS One (2013) 1.03

Integrated analyses identify the involvement of microRNA-26a in epithelial-mesenchymal transition during idiopathic pulmonary fibrosis. Cell Death Dis (2014) 1.03

Identification of serum microRNA profiles in colon cancer. Br J Cancer (2013) 1.02

Systems biology approach to identify transcriptome reprogramming and candidate microRNA targets during the progression of polycystic kidney disease. BMC Syst Biol (2011) 1.02

A systematic analysis of the 3'UTR of HNF4A mRNA reveals an interplay of regulatory elements including miRNA target sites. PLoS One (2011) 1.01

Reconstructing dynamic microRNA-regulated interaction networks. Proc Natl Acad Sci U S A (2013) 1.01

Targeted expression of miR-34a using the T-VISA system suppresses breast cancer cell growth and invasion. Mol Ther (2012) 1.00

Epigenetic silencing of microRNA-199b-5p is associated with acquired chemoresistance via activation of JAG1-Notch1 signaling in ovarian cancer. Oncotarget (2014) 0.99

MicroRNA-100 promotes the autophagy of hepatocellular carcinoma cells by inhibiting the expression of mTOR and IGF-1R. Oncotarget (2014) 0.99

Transcription factor/microRNA axis blocks melanoma invasion program by miR-211 targeting NUAK1. J Invest Dermatol (2013) 0.99

Functional implications of microRNA-215 in TGF-β1-induced phenotypic transition of mesangial cells by targeting CTNNBIP1. PLoS One (2013) 0.99

Genistein downregulates onco-miR-1260b and inhibits Wnt-signalling in renal cancer cells. Br J Cancer (2013) 0.99

MicroRNAs as regulators of metabolic disease: pathophysiologic significance and emerging role as biomarkers and therapeutics. Int J Obes (Lond) (2015) 0.98

MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10. J Cell Mol Med (2015) 0.98

The clinical relevance of the miR-197/CKS1B/STAT3-mediated PD-L1 network in chemoresistant non-small-cell lung cancer. Mol Ther (2015) 0.98

Homo sapiens systemic RNA interference-defective-1 transmembrane family member 1 (SIDT1) protein mediates contact-dependent small RNA transfer and microRNA-21-driven chemoresistance. J Biol Chem (2011) 0.98

The miR-424(322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes Dev (2014) 0.98

MicroRNAs and the glomerulus. Exp Cell Res (2012) 0.97

miR-524-5p suppresses the growth of oncogenic BRAF melanoma by targeting BRAF and ERK2. Oncotarget (2014) 0.97

MicroRNA-based molecular classification of non-BRCA1/2 hereditary breast tumours. Br J Cancer (2013) 0.97

MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization. FEBS Lett (2015) 0.97

Microarray and deep sequencing cross-platform analysis of the mirRNome and isomiR variation in response to epidermal growth factor. BMC Genomics (2013) 0.97

MicroRNAs: target recognition and regulatory functions. Cell (2009) 92.17

MicroRNA expression profiles classify human cancers. Nature (2005) 69.12

The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell (1993) 64.62

The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell (2008) 46.08

A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A (2006) 40.09

The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans. Nature (2000) 39.31

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells. Nat Cell Biol (2007) 37.10

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell (1993) 33.79

Silencing of microRNAs in vivo with 'antagomirs'. Nature (2005) 32.56

The impact of microRNAs on protein output. Nature (2008) 32.39

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet (2008) 32.08

RAS is regulated by the let-7 microRNA family. Cell (2005) 30.24

Wnt/beta-catenin signaling in development and disease. Cell (2006) 30.09

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1. Nat Cell Biol (2008) 24.27

Segmental aneuploidy and the genetic gross structure of the Drosophila genome. Genetics (1972) 22.68

Origins and Mechanisms of miRNAs and siRNAs. Cell (2009) 20.77

Biogenesis of small RNAs in animals. Nat Rev Mol Cell Biol (2009) 19.99

Cancer metastasis: building a framework. Cell (2006) 19.67

Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA. Nature (2000) 19.15

Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits. Nat Rev Cancer (2009) 18.53

Cell signaling by receptor tyrosine kinases. Cell (2000) 18.16

Causes and consequences of microRNA dysregulation in cancer. Nat Rev Genet (2009) 16.58

Connecting microRNA genes to the core transcriptional regulatory circuitry of embryonic stem cells. Cell (2008) 16.38

Impaired microRNA processing enhances cellular transformation and tumorigenesis. Nat Genet (2007) 15.46

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution. Cell (2005) 15.38

Network motifs: theory and experimental approaches. Nat Rev Genet (2007) 15.04

The canonical Notch signaling pathway: unfolding the activation mechanism. Cell (2009) 14.72

Selective blockade of microRNA processing by Lin28. Science (2008) 14.39

let-7 regulates self renewal and tumorigenicity of breast cancer cells. Cell (2007) 13.69

MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology (2007) 13.20

Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs. Nat Rev Genet (2004) 12.97

Small non-coding RNAs in animal development. Nat Rev Mol Cell Biol (2008) 12.35

Regulation of the germinal center response by microRNA-155. Science (2007) 12.25

Extensive post-transcriptional regulation of microRNAs and its implications for cancer. Genes Dev (2006) 11.04

A genetic screen implicates miRNA-372 and miRNA-373 as oncogenes in testicular germ cell tumors. Cell (2006) 11.01

MicroRNA-21 contributes to myocardial disease by stimulating MAP kinase signalling in fibroblasts. Nature (2008) 10.73

Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science (2009) 10.30

SMAD proteins control DROSHA-mediated microRNA maturation. Nature (2008) 9.67

MiR-150 controls B cell differentiation by targeting the transcription factor c-Myb. Cell (2007) 9.33

Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35

MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells. Cell (2009) 8.14

Epidermal homeostasis: a balancing act of stem cells in the skin. Nat Rev Mol Cell Biol (2009) 7.95

The evolution of gene regulation by transcription factors and microRNAs. Nat Rev Genet (2007) 7.92

Modulation of microRNA processing by p53. Nature (2009) 7.88

Beyond PTEN mutations: the PI3K pathway as an integrator of multiple inputs during tumorigenesis. Nat Rev Cancer (2006) 7.53

A double-negative feedback loop between ZEB1-SIP1 and the microRNA-200 family regulates epithelial-mesenchymal transition. Cancer Res (2008) 7.45

MicroRNAs and cancer: short RNAs go a long way. Cell (2009) 7.25

The multiple roles of PTEN in tumor suppression. Cell (2000) 6.71

Hedgehog signaling in development and cancer. Dev Cell (2008) 6.60

miR-126 regulates angiogenic signaling and vascular integrity. Dev Cell (2008) 6.59

p63 Is essential for the proliferative potential of stem cells in stratified epithelia. Cell (2007) 6.50

Gene regulatory networks and the evolution of animal body plans. Science (2006) 6.42

TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol (2007) 6.34

Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity. Nat Cell Biol (2009) 6.03

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell (2009) 6.03

TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell (2009) 5.99

Pervasive regulation of Drosophila Notch target genes by GY-box-, Brd-box-, and K-box-class microRNAs. Genes Dev (2005) 5.78

The Salvador-Warts-Hippo pathway - an emerging tumour-suppressor network. Nat Rev Cancer (2007) 5.78

MicroRNA-mediated feedback and feedforward loops are recurrent network motifs in mammals. Mol Cell (2007) 5.67

A skin microRNA promotes differentiation by repressing 'stemness'. Nature (2008) 5.66

Chromatin structure analyses identify miRNA promoters. Genes Dev (2008) 5.40

Most Caenorhabditis elegans microRNAs are individually not essential for development or viability. PLoS Genet (2007) 5.33

High-throughput mapping of the chromatin structure of human promoters. Nat Biotechnol (2007) 5.24

Dicer1 functions as a haploinsufficient tumor suppressor. Genes Dev (2009) 5.21

Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression. Cell (2008) 5.07

Target protectors reveal dampening and balancing of Nodal agonist and antagonist by miR-430. Science (2007) 4.72

A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell (2005) 4.54

MicroRNA-125b is a novel negative regulator of p53. Genes Dev (2009) 4.43

Revisiting the principles of microRNA target recognition and mode of action. Nat Rev Mol Cell Biol (2009) 4.38

let-7 microRNAs in development, stem cells and cancer. Trends Mol Med (2008) 4.29

Maternal microRNAs are essential for mouse zygotic development. Genes Dev (2007) 4.16

The PTEN-regulating microRNA miR-26a is amplified in high-grade glioma and facilitates gliomagenesis in vivo. Genes Dev (2009) 4.15

A microRNA imparts robustness against environmental fluctuation during development. Cell (2009) 4.08

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN. Nat Cell Biol (2009) 4.05

Antisense-mediated depletion reveals essential and specific functions of microRNAs in Drosophila development. Cell (2005) 3.95

The Hippo pathway regulates the bantam microRNA to control cell proliferation and apoptosis in Drosophila. Cell (2006) 3.81

The Bearded box, a novel 3' UTR sequence motif, mediates negative post-transcriptional regulation of Bearded and Enhancer of split Complex gene expression. Development (1997) 3.75

Let-7 and miR-200 microRNAs: guardians against pluripotency and cancer progression. Cell Cycle (2009) 3.68

The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts. Development (1998) 3.52

Silencing by small RNAs is linked to endosomal trafficking. Nat Cell Biol (2009) 3.25

Primary microRNA transcripts are processed co-transcriptionally. Nat Struct Mol Biol (2008) 3.21

A C. elegans genome-scale microRNA network contains composite feedback motifs with high flux capacity. Genes Dev (2008) 3.19

The bantam microRNA is a target of the hippo tumor-suppressor pathway. Curr Biol (2006) 3.11

Retracted Positive and negative roles of p85 alpha and p85 beta regulatory subunits of phosphoinositide 3-kinase in insulin signaling. J Biol Chem (2003) 3.06

MicroRNAs and the advent of vertebrate morphological complexity. Proc Natl Acad Sci U S A (2008) 3.00

p53--a Jack of all trades but master of none. Nat Rev Cancer (2009) 2.96

Spred is a Sprouty-related suppressor of Ras signalling. Nature (2001) 2.87

Three habits of highly effective signaling pathways: principles of transcriptional control by developmental cell signaling. Genes Dev (2002) 2.77

Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126. Development (2008) 2.71

The phylogenetic distribution of metazoan microRNAs: insights into evolutionary complexity and constraint. J Exp Zool B Mol Dev Evol (2006) 2.63

The establishment of Spemann's organizer and patterning of the vertebrate embryo. Nat Rev Genet (2000) 2.51

Drosophila lacking microRNA miR-278 are defective in energy homeostasis. Genes Dev (2006) 2.26

Pluripotent stem cell lines. Genes Dev (2008) 2.25

Concerted microRNA control of Hedgehog signalling in cerebellar neuronal progenitor and tumour cells. EMBO J (2008) 2.25

MicroRNA control of Nodal signalling. Nature (2007) 2.09

MicroRNA-23b cluster microRNAs regulate transforming growth factor-beta/bone morphogenetic protein signaling and liver stem cell differentiation by targeting Smads. Hepatology (2009) 2.04

Regionally specific induction by the Spemann-Mangold organizer. Nat Rev Genet (2004) 1.92

From nuclear transfer to nuclear reprogramming: the reversal of cell differentiation. Annu Rev Cell Dev Biol (2006) 1.91

Coherent but overlapping expression of microRNAs and their targets during vertebrate development. Genes Dev (2009) 1.77

The microRNA miR-8 is a conserved negative regulator of Wnt signaling. Proc Natl Acad Sci U S A (2008) 1.76

Role of YAP/TAZ in mechanotransduction. Nature (2011) 11.56

Mapping Wnt/beta-catenin signaling during mouse development and in colorectal tumors. Proc Natl Acad Sci U S A (2003) 7.60

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis. Cell (2009) 6.03

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell (2011) 5.06

A MicroRNA targeting dicer for metastasis control. Cell (2010) 4.81

FAM/USP9x, a deubiquitinating enzyme essential for TGFbeta signaling, controls Smad4 monoubiquitination. Cell (2009) 4.11

Links between tumor suppressors: p53 is required for TGF-beta gene responses by cooperating with Smads. Cell (2003) 3.45

A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors. Cell (2013) 3.17

Glycogen synthase kinase-3beta haploinsufficiency mimics the behavioral and molecular effects of lithium. J Neurosci (2004) 3.12

Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol (2012) 3.07

Role of TAZ as mediator of Wnt signaling. Cell (2012) 3.05

Emilin1 links TGF-beta maturation to blood pressure homeostasis. Cell (2006) 2.84

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol (2005) 2.73

Germ-layer specification and control of cell growth by Ectodermin, a Smad4 ubiquitin ligase. Cell (2005) 2.66

Beta-catenin is required for endothelial-mesenchymal transformation during heart cushion development in the mouse. J Cell Biol (2004) 2.57

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors. Nature (2012) 2.46

Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol (2007) 2.26

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction. Dev Cell (2009) 2.17

MicroRNA control of Nodal signalling. Nature (2007) 2.09

Activation of beta-catenin signaling programs embryonic epidermis to hair follicle fate. Development (2008) 1.96

BMP signaling controls muscle mass. Nat Genet (2013) 1.68

Integration of TGF-beta and Ras/MAPK signaling through p53 phosphorylation. Science (2007) 1.65

USP15 is a deubiquitylating enzyme for receptor-activated SMADs. Nat Cell Biol (2011) 1.61

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis. Development (2006) 1.55

Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression. Development (2009) 1.39

Negative control of Smad activity by ectodermin/Tif1gamma patterns the mammalian embryo. Development (2010) 1.35

Cooperating pre-T-cell receptor and TCF-1-dependent signals ensure thymocyte survival. Blood (2005) 1.25

Targeting triple negative breast cancer: is p53 the answer? Cancer Treat Rev (2013) 1.23

Developmental phenotypes and reduced Wnt signaling in mice deficient for pygopus 2. Genesis (2007) 1.15

Rebuilding pluripotency from primordial germ cells. Stem Cell Reports (2013) 1.09

Epithelial-mesenchymal transition in malignant mesothelioma. Mod Pathol (2011) 1.05

Convergence of p53 and TGF-beta signaling networks. Cancer Lett (2004) 1.05

Identification of new p63 targets in human keratinocytes. Cell Cycle (2006) 0.97

Activation of the Wnt-beta catenin pathway in a cell population on the surface of the forebrain is essential for the establishment of olfactory axon connections. J Neurosci (2007) 0.92

Fat facets deubiquitylation of Medea/Smad4 modulates interpretation of a Dpp morphogen gradient. Development (2012) 0.87

miRNAs and morphogen gradients. Curr Opin Cell Biol (2011) 0.86

Self-regulation of the head-inducing properties of the Spemann organizer. Proc Natl Acad Sci U S A (2012) 0.82

LIF-ting Hippo averts metastasis. Nat Med (2012) 0.78

Unilateral rosacea in patients with facial nerve palsy: a mere example of immunocompromised district. J Dermatol (2013) 0.75

Twists of fate. Sci Am (2014) 0.75