Published in Cell Mol Life Sci on January 29, 2014
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Oligonucleotide-based strategies to combat polyglutamine diseases. Nucleic Acids Res (2014) 0.90
Interactions between cancer cells and normal cells via miRNAs in extracellular vesicles. Cell Mol Life Sci (2015) 0.87
Lithium protects against paraquat neurotoxicity by NRF2 activation and miR-34a inhibition in SH-SY5Y cells. Front Cell Neurosci (2015) 0.87
Modulation of miRNAs in Pulmonary Hypertension. Int J Hypertens (2015) 0.86
The potential of microRNAs in personalized medicine against cancers. Biomed Res Int (2014) 0.84
RNA imaging in living cells - methods and applications. RNA Biol (2014) 0.82
Transmissible gastroenteritis virus (TGEV) infection alters the expression of cellular microRNA species that affect transcription of TGEV gene 7. Int J Biol Sci (2015) 0.81
MicroRNAs regulate tight junction proteins and modulate epithelial/endothelial barrier functions. Tissue Barriers (2014) 0.81
Mini but mighty: microRNAs in the pathobiology of periodontal disease. Periodontol 2000 (2015) 0.80
A simple metric of promoter architecture robustly predicts expression breadth of human genes suggesting that most transcription factors are positive regulators. Genome Biol (2014) 0.80
Current understanding of the role of microRNAs in spinocerebellar ataxias. Cerebellum Ataxias (2014) 0.78
An Improved microRNA Annotation of the Canine Genome. PLoS One (2016) 0.77
Small RNA Detection by in Situ Hybridization Methods. Int J Mol Sci (2015) 0.77
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Endogenous and tumour-derived microRNAs regulate cross-presentation in dendritic cells and consequently cytotoxic T cell function. Cytotechnology (2016) 0.75
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MicroRNA-directed cleavage of HOXB8 mRNA. Science (2004) 18.33
Fast and effective prediction of microRNA/target duplexes. RNA (2004) 18.10
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Modulation of hepatitis C virus RNA abundance by a liver-specific MicroRNA. Science (2005) 16.84
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TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature (2005) 13.44
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Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. RNA (2004) 11.52
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Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science (2009) 10.30
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Treatment of HCV infection by targeting microRNA. N Engl J Med (2013) 9.91
MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation. Nature (2008) 9.83
Intronic microRNA precursors that bypass Drosha processing. Nature (2007) 9.65
A long noncoding RNA controls muscle differentiation by functioning as a competing endogenous RNA. Cell (2011) 9.24
Natural RNA circles function as efficient microRNA sponges. Nature (2013) 8.93
Potent effect of target structure on microRNA function. Nat Struct Mol Biol (2007) 8.92
CLIP identifies Nova-regulated RNA networks in the brain. Science (2003) 8.88
mRNA degradation by miRNAs and GW182 requires both CCR4:NOT deadenylase and DCP1:DCP2 decapping complexes. Genes Dev (2006) 8.78
Circular RNAs are a large class of animal RNAs with regulatory potency. Nature (2013) 8.54
Characterization of Dicer-deficient murine embryonic stem cells. Proc Natl Acad Sci U S A (2005) 8.35
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Structural basis for overhang-specific small interfering RNA recognition by the PAZ domain. Nature (2004) 7.63
A role for the P-body component GW182 in microRNA function. Nat Cell Biol (2005) 7.54
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat Struct Mol Biol (2005) 7.49
RNAhybrid: microRNA target prediction easy, fast and flexible. Nucleic Acids Res (2006) 7.39
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science (2007) 7.15
Mammalian microRNAs: experimental evaluation of novel and previously annotated genes. Genes Dev (2010) 7.14
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA. Cell (2007) 7.06
Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs. Cell (2011) 7.02
The crystal structure of the Argonaute2 PAZ domain reveals an RNA binding motif in RNAi effector complexes. Nat Struct Biol (2003) 6.90
RNA polymerase III transcribes human microRNAs. Nat Struct Mol Biol (2006) 6.81
Short RNAs repress translation after initiation in mammalian cells. Mol Cell (2006) 6.70
Purified Argonaute2 and an siRNA form recombinant human RISC. Nat Struct Mol Biol (2005) 6.64
MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. Mol Cell (2008) 6.58
Translation repression in human cells by microRNA-induced gene silencing requires RCK/p54. PLoS Biol (2006) 6.41
A dicer-independent miRNA biogenesis pathway that requires Ago catalysis. Nature (2010) 6.37
Processing of intronic microRNAs. EMBO J (2007) 6.32
CLIP: a method for identifying protein-RNA interaction sites in living cells. Methods (2005) 6.26
Identification of novel argonaute-associated proteins. Curr Biol (2005) 6.13
Illuminating the silence: understanding the structure and function of small RNAs. Nat Rev Mol Cell Biol (2007) 6.11
TUT4 in concert with Lin28 suppresses microRNA biogenesis through pre-microRNA uridylation. Cell (2009) 5.99
A novel miRNA processing pathway independent of Dicer requires Argonaute2 catalytic activity. Science (2010) 5.84
TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing. EMBO Rep (2005) 5.82
An extensive microRNA-mediated network of RNA-RNA interactions regulates established oncogenic pathways in glioblastoma. Cell (2011) 5.75
Mammalian mirtron genes. Mol Cell (2007) 5.75
Crystal structures of RNase H bound to an RNA/DNA hybrid: substrate specificity and metal-dependent catalysis. Cell (2005) 5.43
MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat Rev Genet (2012) 5.38
MicroRNAs control translation initiation by inhibiting eukaryotic initiation factor 4E/cap and poly(A) tail function. Proc Natl Acad Sci U S A (2005) 5.35
A phosphorylated cytoplasmic autoantigen, GW182, associates with a unique population of human mRNAs within novel cytoplasmic speckles. Mol Biol Cell (2002) 5.34
The many pathways of RNA degradation. Cell (2009) 5.31
miR-24 Inhibits cell proliferation by targeting E2F2, MYC, and other cell-cycle genes via binding to "seedless" 3'UTR microRNA recognition elements. Mol Cell (2009) 5.22
An analysis of human microRNA and disease associations. PLoS One (2008) 5.21
Dual role for argonautes in microRNA processing and posttranscriptional regulation of microRNA expression. Cell (2007) 5.19
A search for conserved sequences in coding regions reveals that the let-7 microRNA targets Dicer within its coding sequence. Proc Natl Acad Sci U S A (2008) 5.11
Distance constraints between microRNA target sites dictate efficacy and cooperativity. Nucleic Acids Res (2007) 4.91
RISC is a 5' phosphomonoester-producing RNA endonuclease. Genes Dev (2004) 4.73
A Slicer-independent role for Argonaute 2 in hematopoiesis and the microRNA pathway. Genes Dev (2007) 4.69
Biochemical and genetic interaction between the fragile X mental retardation protein and the microRNA pathway. Nat Neurosci (2004) 4.69
Sorting of Drosophila small silencing RNAs. Cell (2007) 4.67
RNA structure of trinucleotide repeats associated with human neurological diseases. Nucleic Acids Res (2003) 2.34
Cellular toxicity of expanded RNA repeats: focus on RNA foci. Hum Mol Genet (2011) 2.05
Structural features of microRNA (miRNA) precursors and their relevance to miRNA biogenesis and small interfering RNA/short hairpin RNA design. J Biol Chem (2004) 2.01
Ribonuclease dicer cleaves triplet repeat hairpins into shorter repeats that silence specific targets. Mol Cell (2007) 1.87
Mutant CAG repeats of Huntingtin transcript fold into hairpins, form nuclear foci and are targets for RNA interference. Nucleic Acids Res (2011) 1.77
Structural basis of microRNA length variety. Nucleic Acids Res (2010) 1.56
CAG repeats mimic CUG repeats in the misregulation of alternative splicing. Nucleic Acids Res (2011) 1.42
Molecular architecture of CAG repeats in human disease related transcripts. J Mol Biol (2004) 1.37
Trinucleotide repeats in human genome and exome. Nucleic Acids Res (2010) 1.35
Structural diversity of triplet repeat RNAs. J Biol Chem (2010) 1.29
CAG repeats containing CAA interruptions form branched hairpin structures in spinocerebellar ataxia type 2 transcripts. J Biol Chem (2004) 1.29
Triplet repeat RNA structure and its role as pathogenic agent and therapeutic target. Nucleic Acids Res (2011) 1.29
Structural insights into CUG repeats containing the 'stretched U-U wobble': implications for myotonic dystrophy. Nucleic Acids Res (2009) 1.28
Inhibition of mutant huntingtin expression by RNA duplex targeting expanded CAG repeats. Nucleic Acids Res (2011) 1.27
Repetitive sequences that shape the human transcriptome. FEBS Lett (2004) 1.19
Atomic resolution structure of CAG RNA repeats: structural insights and implications for the trinucleotide repeat expansion diseases. Nucleic Acids Res (2010) 1.18
The role of Dicer protein partners in the processing of microRNA precursors. PLoS One (2011) 1.15
Structures of trinucleotide repeats in human transcripts and their functional implications. Nucleic Acids Res (2003) 1.14
Facile FMR1 mRNA structure regulation by interruptions in CGG repeats. Nucleic Acids Res (2005) 1.14
Sequence-non-specific effects of RNA interference triggers and microRNA regulators. Nucleic Acids Res (2009) 1.11
The role of the precursor structure in the biogenesis of microRNA. Cell Mol Life Sci (2011) 1.11
Patterns of CAG repeat interruptions in SCA1 and SCA2 genes in relation to repeat instability. Hum Mutat (2004) 1.10
Crystal structures of CGG RNA repeats with implications for fragile X-associated tremor ataxia syndrome. Nucleic Acids Res (2011) 1.06
Structural determinants of BRCA1 translational regulation. J Biol Chem (2002) 1.05
Imperfect CAG repeats form diverse structures in SCA1 transcripts. J Biol Chem (2004) 1.03
Genotyping of simple sequence repeats--factors implicated in shadow band generation revisited. Electrophoresis (2006) 0.98
Structure analysis of microRNA precursors. Methods Mol Biol (2006) 0.97
Copy number variation of microRNA genes in the human genome. BMC Genomics (2011) 0.97
CAG repeat RNA as an auxiliary toxic agent in polyglutamine disorders. RNA Biol (2011) 0.97
Triplet repeats in transcripts: structural insights into RNA toxicity. Biol Chem (2012) 0.96
RNA toxicity in polyglutamine disorders: concepts, models, and progress of research. J Mol Med (Berl) (2013) 0.94
RNAimmuno: a database of the nonspecific immunological effects of RNA interference and microRNA reagents. RNA (2012) 0.94
Hairpin structure within the 3'UTR of DNA polymerase beta mRNA acts as a post-transcriptional regulatory element and interacts with Hax-1. Nucleic Acids Res (2007) 0.93
An evaluation of oligonucleotide-based therapeutic strategies for polyQ diseases. BMC Mol Biol (2012) 0.91
High-resolution northern blot for a reliable analysis of microRNAs and their precursors. ScientificWorldJournal (2011) 0.91
Structural aspects of microRNA biogenesis. IUBMB Life (2004) 0.90
Crystallographic characterization of CCG repeats. Nucleic Acids Res (2012) 0.90
Recent advances in understanding of the immunological off-target effects of siRNA. Curr Gene Ther (2011) 0.90
CAG and CTG repeat polymorphism in exons of human genes shows distinct features at the expandable loci. Hum Mutat (2007) 0.90
Trinucleotide repeat system for sequence specificity analysis of RNA structure probing reagents. Anal Biochem (2010) 0.89
Regulation of huntingtin gene expression by miRNA-137, -214, -148a, and their respective isomiRs. Int J Mol Sci (2013) 0.88
Mouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II. Mol Neurobiol (2012) 0.86
Northern blotting analysis of microRNAs, their precursors and RNA interference triggers. BMC Mol Biol (2011) 0.85
Mouse ataxin-3 functional knock-out model. Neuromolecular Med (2010) 0.84
Mouse models of polyglutamine diseases: review and data table. Part I. Mol Neurobiol (2012) 0.84
Self-duplexing CUG repeats selectively inhibit mutant huntingtin expression. Nucleic Acids Res (2013) 0.82
RNA imaging in living cells - methods and applications. RNA Biol (2014) 0.82
Analysis of microRNA length variety generated by recombinant human Dicer. Methods Mol Biol (2013) 0.79
Trinucleotide repeats: triggers for genomic disorders? Genome Med (2010) 0.78
Diced triplets expose neurons to RISC. PLoS Genet (2012) 0.78
Optimum sample medium for single-nucleotide polymorphism and mutation detection by capillary electrophoresis. Electrophoresis (2004) 0.78
Characterization of a naturally occurring truncated Dicer. Mol Biol Rep (2015) 0.76
RNA structure analysis assisted by capillary electrophoresis. Nucleic Acids Res (2002) 0.76
Pseudouridylation of U(35) in the anticodon of Arabidopsis thaliana pre-tRNA(Tyr) depends on length rather than structure of an intron. Biochim Biophys Acta (2002) 0.76
Expression characteristics of triplet repeat-containing RNAs and triplet repeat-interacting proteins in human tissues. Acta Biochim Pol (2008) 0.75
Pathogenesis of spinocerebellar ataxias viewed from the RNA perspective. Cerebellum (2005) 0.75
Structural factors determining DNA length limitations in conformation-sensitive mutation detection methods. Electrophoresis (2005) 0.75
Economical protocol for combined single-strand conformation polymorphism and heteroduplex analysis on a standard capillary electrophoresis apparatus. Methods Mol Biol (2010) 0.75
Accurate and sensitive analysis of triplet repeat expansions by capillary electrophoresis. Electrophoresis (2005) 0.75
Rapid heteroduplex analysis by capillary electrophoresis. Clin Chim Acta (2005) 0.75