Published in Proc Natl Acad Sci U S A on May 01, 1991
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cDNA selection: efficient PCR approach for the selection of cDNAs encoded in large chromosomal DNA fragments. Proc Natl Acad Sci U S A (1991) 3.31
Positional cloning of ZNF217 and NABC1: genes amplified at 20q13.2 and overexpressed in breast carcinoma. Proc Natl Acad Sci U S A (1998) 2.80
Inactivating mutations in an SH2 domain-encoding gene in X-linked lymphoproliferative syndrome. Proc Natl Acad Sci U S A (1998) 2.46
Mutations of CD40 gene cause an autosomal recessive form of immunodeficiency with hyper IgM. Proc Natl Acad Sci U S A (2001) 2.39
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Forward and reverse genetic approaches to behavior in the mouse. Science (1994) 2.20
Tricellulin is a tight-junction protein necessary for hearing. Am J Hum Genet (2006) 2.05
Identification of the TCL1 gene involved in T-cell malignancies. Proc Natl Acad Sci U S A (1994) 2.02
Structure and expression of the hairless gene of mice. Proc Natl Acad Sci U S A (1994) 1.85
An efficient strategy to isolate full-length cDNAs based on an mRNA cap retention procedure (CAPture). Mol Cell Biol (1995) 1.70
Cloning and characterization of developmental endothelial locus-1: an embryonic endothelial cell protein that binds the alphavbeta3 integrin receptor. Genes Dev (1998) 1.69
Elements regulating an alternatively spliced exon of the rat fibronectin gene. Mol Cell Biol (1993) 1.54
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RNA splicing in Borna disease virus, a nonsegmented, negative-strand RNA virus. J Virol (1994) 1.50
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Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3. Am J Hum Genet (1996) 1.32
Construction of a BAC contig map of chromosome 16q by two-dimensional overgo hybridization. Genome Res (2000) 1.32
The selective isolation of novel cDNAs encoded by the regions surrounding the human interleukin 4 and 5 genes. Nucleic Acids Res (1992) 1.26
Construction of a yeast artificial chromosome contig spanning the spinal muscular atrophy disease gene region. Proc Natl Acad Sci U S A (1993) 1.21
Noncoding mutations of HGF are associated with nonsyndromic hearing loss, DFNB39. Am J Hum Genet (2009) 1.21
A unique human gene that spans over 230 kb in the human chromosome 8p11-12 and codes multiple family proteins sharing RNA-binding motifs. Proc Natl Acad Sci U S A (1996) 1.20
Establishment of a highly sensitive and specific exon-trapping system. Proc Natl Acad Sci U S A (1992) 1.17
Exome sequencing identifies a REEP1 mutation involved in distal hereditary motor neuropathy type V. Am J Hum Genet (2012) 1.16
Isolation and characterization of a MAGE gene family in the Xp21.3 region. Proc Natl Acad Sci U S A (1995) 1.13
Efficient selection of 3'-terminal exons from vertebrate DNA. Nucleic Acids Res (1993) 1.10
Construction of a 2.8-megabase yeast artificial chromosome contig and cloning of the human methylthioadenosine phosphorylase gene from the tumor suppressor region on 9p21. Proc Natl Acad Sci U S A (1995) 1.07
A genome-wide survey of switchgrass genome structure and organization. PLoS One (2012) 1.03
Conservation of synteny between the genome of the pufferfish (Fugu rubripes) and the region on human chromosome 14 (14q24.3) associated with familial Alzheimer disease (AD3 locus) Proc Natl Acad Sci U S A (1996) 1.00
A cluster of four receptor-like genes resides in the Vf locus that confers resistance to apple scab disease. Genetics (2002) 0.99
A 1.5-megabase yeast artificial chromosome contig from human chromosome 10q11.2 connecting three genetic loci (RET, D10S94, and D10S102) closely linked to the MEN2A locus. Proc Natl Acad Sci U S A (1993) 0.98
Novel mutations affecting LRP5 splicing in patients with osteoporosis-pseudoglioma syndrome (OPPG). Eur J Hum Genet (2011) 0.97
A transcription map of the 6p22.3 reading disability locus identifying candidate genes. BMC Genomics (2003) 0.96
Genes in one megabase of the HLA class I region. Proc Natl Acad Sci U S A (1993) 0.94
Epidermolysis bullosa simplex associated with pyloric atresia is a novel clinical subtype caused by mutations in the plectin gene (PLEC1). J Mol Diagn (2005) 0.93
Systematic screening of an arrayed cDNA library by PCR. Proc Natl Acad Sci U S A (1995) 0.92
Molecular analysis of radiation-induced albino (c)-locus mutations that cause death at preimplantation stages of development. Genetics (1993) 0.91
A gene map of the Best's vitelliform macular dystrophy region in chromosome 11q12-q13.1. Genome Res (1998) 0.89
Rapid isolation of cDNA by hybridization. Proc Natl Acad Sci U S A (1998) 0.87
An integrated approach for identifying and mapping human genes. Proc Natl Acad Sci U S A (1993) 0.87
A YAC contig encompassing the Treacher Collins syndrome critical region at 5q31.3-32. Am J Hum Genet (1994) 0.86
Direct selection of cDNAs using whole chromosomes. Nucleic Acids Res (1995) 0.86
A murine TSPY. Chromosome Res (1998) 0.86
High-resolution physical map and transcript identification of a prostate cancer deletion interval on 8p22. Genome Res (2000) 0.86
Isolation of novel non-HLA gene fragments from the hemochromatosis region (6p21.3) by cDNA hybridization selection. Am J Hum Genet (1994) 0.86
Physical mapping, cloning, and identification of genes within a 500-kb region containing BRCA1. Proc Natl Acad Sci U S A (1995) 0.85
Preferential isolation of DNA fragments associated with CpG islands. Proc Natl Acad Sci U S A (1995) 0.85
The genes encoding the peripheral cannabinoid receptor and alpha-L-fucosidase are located near a newly identified common virus integration site, Evi11. J Virol (1997) 0.84
The development of chromosome microdissection and microcloning technique and its applications in genomic research. Curr Genomics (2007) 0.83
Scanning for genes in large genomic regions: cosmid-based exon trapping of multiple exons in a single product. Nucleic Acids Res (1996) 0.83
Identification of a precursor genomic segment that provided a sequence unique to glycophorin B and E genes. Proc Natl Acad Sci U S A (1993) 0.82
Signal-exon trap: a novel method for the identification of signal sequences from genomic DNA. Nucleic Acids Res (2000) 0.82
Construction of a genomic DNA 'feature map' by sequencing from nested deletions: application to the HLA class I region. Nucleic Acids Res (1995) 0.82
Isolation of yeast artificial chromosomes free of endogenous yeast chromosomes: construction of alternate hosts with defined karyotypic alterations. Proc Natl Acad Sci U S A (1995) 0.82
The exon trapping assay partly discriminates against alternatively spliced exons. Nucleic Acids Res (1993) 0.81
Construction of an approximately 700-kb transcript map around the familial Mediterranean fever locus on human chromosome 16p13.3. Genome Res (1998) 0.80
Direct selection of DNA sequences conserved between species. Nucleic Acids Res (1993) 0.80
Novel transcripts discovered by mining genomic DNA from defined regions of bovine chromosome 6. BMC Genomics (2009) 0.80
Specific isolation of 3'-terminal exons of human genes by exon trapping. Nucleic Acids Res (1994) 0.79
Direct isolation of genes encoded within a homogeneously staining region by chromosome microdissection. Proc Natl Acad Sci U S A (1994) 0.79
High-resolution physical mapping by combined Alu-hybridization/PCR screening: construction of a yeast artificial chromosome map covering 31 centimorgans in 3p21-p14. Proc Natl Acad Sci U S A (1996) 0.79
A 4.5-megabase yeast artificial chromosome contig from human chromosome 13q14.3 ordering 9 polymorphic microsatellites (22 sequence-tagged sites) tightly linked to the Wilson disease locus. Proc Natl Acad Sci U S A (1993) 0.78
Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant. J Neurochem (2010) 0.76
Isolation of coding sequences from bovine cosmids by means of exon trapping. Mamm Genome (1997) 0.76
Isolation of human transcripts expressed in hamster cells from YACs by cDNA representational difference analysis. Genome Res (1999) 0.75
Direct isolation of human transcribed sequences from yeast artificial chromosomes through the application of RNA fingerprinting. Proc Natl Acad Sci U S A (1997) 0.75
Expression of peptides encoded by exons in cloned mammalian DNA. Nucleic Acids Res (1996) 0.75
Improved method of gene detection using exon amplification. Nucleic Acids Res (1994) 0.75
Exon-enriched probe derived from a human chromosome 21 YAC by exon-amplification. Nucleic Acids Res (1993) 0.75
New nucleotide sequence data on the EMBL File Server. Nucleic Acids Res (1991) 0.75
High-resolution transcript map of the region spanning D12S1629 and D12S312 at chromosome 12q13: triple A syndrome-linked region. Genome Res (2000) 0.75
Exome sequencing revealed a splice site variant in the IQCE gene underlying post-axial polydactyly type A restricted to lower limb. Eur J Hum Genet (2017) 0.75
Localization of the casein kinase II beta-subunit gene within the mouse H-2 complex class III region and comparison of expression with Bat genes. Mamm Genome (1997) 0.75
CAND3: A ubiquitously expressed gene immediately adjacent and in opposite transcriptional orientation to the ATM gene at 1lq23.1. Mamm Genome (1997) 0.75
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CpG-rich islands and the function of DNA methylation. Nature (1986) 24.90
Identification of the cystic fibrosis gene: chromosome walking and jumping. Science (1989) 21.46
Splicing of messenger RNA precursors. Annu Rev Biochem (1986) 14.41
Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell (1984) 13.91
Polymerase chain reaction with single-sided specificity: analysis of T cell receptor delta chain. Science (1989) 9.01
Identification of a chromosome 18q gene that is altered in colorectal cancers. Science (1990) 8.32
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus. Cell (1990) 8.30
Regulation by HIV Rev depends upon recognition of splice sites. Cell (1989) 7.13
Isolation of candidate cDNAs for portions of the Duchenne muscular dystrophy gene. Nature (1986) 6.45
Immunodeficiency virus rev trans-activator modulates the expression of the viral regulatory genes. Nature (1988) 6.28
Comparison of intron-dependent and intron-independent gene expression. Mol Cell Biol (1988) 4.75
The sex-determining region of the human Y chromosome encodes a finger protein. Cell (1987) 4.43
Unusual splice sites revealed by mutagenic inactivation of an authentic splice site of the rabbit beta-globin gene. Nature (1983) 4.38
Molecular characterization of the human excision repair gene ERCC-1: cDNA cloning and amino acid homology with the yeast DNA repair gene RAD10. Cell (1986) 3.17
Hypomethylation of ras oncogenes in primary human cancers. Biochem Biophys Res Commun (1983) 2.41
Loss of intervening sequences in genomic mouse alpha-globin DNA inserted in an infectious retrovirus vector. Nature (1982) 2.38
Splicing of intervening sequences introduced into an infectious retroviral vector. J Mol Appl Genet (1982) 2.36
A gene chimaera of SV40 and mouse beta-globin is transcribed and properly spliced. Nature (1981) 2.35
Spontaneous splicing mutations at the dihydrofolate reductase locus in Chinese hamster ovary cells. Mol Cell Biol (1986) 2.19
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Efficient and stable expression of recombinant fibronectin polypeptides. Proc Natl Acad Sci U S A (1987) 1.21
Isolation of human transcribed sequences from human-rodent somatic cell hybrids. Science (1989) 1.21
Direct cloning of human transcripts with HnRNA from hybrid cell lines. Science (1990) 1.03
Functional expression of the genomic DNA sequences encoding mouse Na,K-ATPase alpha 1 gene by cotransfection of overlapping genomic DNA segments. Mol Cell Biol (1990) 0.85
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Detection of two restriction endonuclease activities in Haemophilus parainfluenzae using analytical agarose--ethidium bromide electrophoresis. Biochemistry (1973) 43.61
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Five intermediate complexes in transcription initiation by RNA polymerase II. Cell (1989) 9.22
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A lymphoid-specific protein binding to the octamer motif of immunoglobulin genes. Nature (1986) 8.64
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The sequences of an expressed rat alpha-tubulin gene and a pseudogene with an inserted repetitive element. Nature (1982) 4.42
Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor. Science (1987) 4.32
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