Published in Proc Natl Acad Sci U S A on December 01, 1984
Genes for low-molecular-weight heat shock proteins of soybeans: sequence analysis of a multigene family. Mol Cell Biol (1985) 2.30
Ontogenic activation of a fusion gene introduced into sea urchin eggs. Proc Natl Acad Sci U S A (1987) 1.69
Heat shock and the heat shock proteins. Biochem J (1986) 1.64
Comparison of the late H1 histone genes of the sea urchins Lytechinus pictus and Strongelocentrotus purpuratus. Nucleic Acids Res (1986) 1.09
The embryonic enhancer-binding protein SSAP contains a novel DNA-binding domain which has homology to several RNA-binding proteins. Mol Cell Biol (1995) 1.00
An embryonic enhancer determines the temporal activation of a sea urchin late H1 gene. Mol Cell Biol (1989) 0.91
Purification and characterization of the stage-specific embryonic enhancer-binding protein SSAP-1. Mol Cell Biol (1993) 0.80
Developmental expression of synthetic cis-regulatory systems composed of spatial control elements from two different genes. Proc Natl Acad Sci U S A (1996) 0.80
Rapid intranasal delivery of chloramphenicol acetyltransferase in the active form to different brain regions as a model for enzyme therapy in the CNS. J Neurosci Methods (2015) 0.79
Functional conservation of cis-regulatory elements of heat-shock genes over long evolutionary distances. PLoS One (2011) 0.79
Do echinoderm genomes measure up? Mar Genomics (2015) 0.76
Temporal activation of the sea urchin late H1 gene requires stage-specific phosphorylation of the embryonic transcription factor SSAP. Mol Cell Biol (1999) 0.75
Activity of heat shock genes' promoters in thermally contrasting animal species. PLoS One (2015) 0.75
Eric Davidson: Steps to a gene regulatory network for development. Dev Biol (2016) 0.75
Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol Cell Biol (1982) 116.75
A regulatory upstream promoter element in the Drosophila hsp 70 heat-shock gene. Cell (1982) 14.32
High efficiency transformation by direct microinjection of DNA into cultured mammalian cells. Cell (1980) 8.30
Protein synthesis in salivary glands of Drosophila melanogaster: relation to chromosome puffs. J Mol Biol (1974) 6.60
Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus. J Bacteriol (1968) 6.28
Localization of RNA from heat-induced polysomes at puff sites in Drosophila melanogaster. Proc Natl Acad Sci U S A (1975) 5.29
A synthetic heat-shock promoter element confers heat-inducibility on the herpes simplex virus thymidine kinase gene. EMBO J (1982) 5.19
Production of human beta interferon in insect cells infected with a baculovirus expression vector. Mol Cell Biol (1983) 5.00
Transient expression of genes introduced into cultured cells of Drosophila. Proc Natl Acad Sci U S A (1983) 3.93
Integration, transcription, and control of a Drosophila heat shock gene in mouse cells. Proc Natl Acad Sci U S A (1981) 3.70
Primary structure of a chloramphenicol acetyltransferase specified by R plasmids. Nature (1980) 3.63
Regulation of heat-shock genes: a DNA sequence upstream of Drosophila hsp70 genes is essential for their induction in monkey cells. EMBO J (1982) 2.76
Copurification of actin and desmin from chicken smooth muscle and their copolymerization in vitro to intermediate filaments. J Cell Biol (1979) 2.74
Transcription of a Drosophila heat shock gene is heat-induced in Xenopus oocytes. Proc Natl Acad Sci U S A (1982) 2.47
Parallel changes in puffing activity and patterns of protein synthesis in salivary glands of Drosophila. Proc Natl Acad Sci U S A (1975) 2.03
Heat-shock proteins are associated with hnRNA in Drosophila melanogaster tissue culture cells. EMBO J (1983) 2.00
Regulated transcription of the genes for actin and heat-shock proteins in cultured Drosophila cells. J Cell Biol (1981) 1.95
Expression of a Drosophila heat-shock protein in Xenopus oocytes: conserved and divergent regulatory signals. EMBO J (1982) 1.72
Direct measurement of histone peptide elongation rate in cleaving sea urchin embryos. Biochim Biophys Acta (1982) 0.83
Repeated sequences in DNA. Hundreds of thousands of copies of DNA sequences have been incorporated into the genomes of higher organisms. Science (1968) 30.37
Hedgehog signaling in animal development: paradigms and principles. Genes Dev (2001) 14.75
Gene regulation for higher cells: a theory. Science (1969) 14.19
High-Resolution Density Gradient Sedimentation Analysis. Science (1960) 12.12
Analysis of repeating DNA sequences by reassociation. Methods Enzymol (1974) 10.63
Modification of gene activity in mouse embryos in utero by a tamoxifen-inducible form of Cre recombinase. Curr Biol (1998) 10.58
Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development (2001) 9.00
SYNTHESIS OF NASCENT PROTEIN BY RIBOSOMES IN ESCHERICHIA COLI. Proc Natl Acad Sci U S A (1959) 8.76
Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation. Genes Dev (1999) 8.43
Fate of the mammalian cranial neural crest during tooth and mandibular morphogenesis. Development (2000) 8.07
Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell (1993) 7.41
Fate of the mammalian cardiac neural crest. Development (2000) 6.79
Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature (1994) 6.57
Rates of DNA sequence evolution differ between taxonomic groups. Science (1986) 6.46
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice. Science (2003) 6.35
A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development (1999) 5.85
Genomic cis-regulatory logic: experimental and computational analysis of a sea urchin gene. Science (1998) 5.66
Sonic hedgehog signaling is essential for hair development. Curr Biol (1998) 5.58
The hardwiring of development: organization and function of genomic regulatory systems. Development (1997) 5.55
Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol (1995) 5.36
Regulation of gene expression: possible role of repetitive sequences. Science (1979) 5.34
Repetitive and non-repetitive DNA sequences and a speculation on the origins of evolutionary novelty. Q Rev Biol (1971) 5.18
Reduction in the rate of DNA reassociation by sequence divergence. J Mol Biol (1973) 4.94
Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development (2001) 4.89
Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton. Science (1998) 4.72
Sonic hedgehog regulates growth and morphogenesis of the tooth. Development (2000) 4.71
Sonic hedgehog--regulated oligodendrocyte lineage genes encoding bHLH proteins in the mammalian central nervous system. Neuron (2000) 4.17
Female development in mammals is regulated by Wnt-4 signalling. Nature (1999) 4.13
Organization, transcription, and regulation in the animal genome. Q Rev Biol (1973) 3.95
Sources and evolution of human Alu repeated sequences. Proc Natl Acad Sci U S A (1988) 3.95
Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein. Nature (1999) 3.87
Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev (1994) 3.77
Hedgehog signals regulate multiple aspects of gastrointestinal development. Development (2000) 3.77
Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development (1993) 3.66
Nucleotide sequence repetition: a rapidly reassociating fraction of mouse DNA. Science (1966) 3.55
Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev (1998) 3.46
Structural gene sets active in embryos and adult tissues of the sea urchin. Cell (1976) 3.38
Essential function of Wnt-4 in mammary gland development downstream of progesterone signaling. Genes Dev (2000) 3.30
Sonic hedgehog regulates branching morphogenesis in the mammalian lung. Curr Biol (1998) 3.29
Expression of the proto-oncogene int-1 is restricted to specific neural cells in the developing mouse embryo. Cell (1987) 3.29
The Synthesis of Ribosomes in E. coli: I. The Incorporation of C-Uracil into the Metabolic Pool and RNA. Biophys J (1962) 3.16
The Synthesis of Ribosomes in E. coli: III. Synthesis of Ribosomal RNA. Biophys J (1962) 3.14
T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev (1999) 3.13
A program for least squares analysis of reassociation and hybridization data. Nucleic Acids Res (1977) 3.13
Wnt signalling required for expansion of neural crest and CNS progenitors. Nature (1997) 3.11
General interspersion of repetitive with non-repetitive sequence elements in the DNA of Xenopus. J Mol Biol (1973) 3.08
The single-copy DNA sequence polymorphism of the sea urchin Strongylocentrotus purpuratus. Cell (1978) 3.06
Noggin is a mesenchymally derived stimulator of hair-follicle induction. Nat Cell Biol (1999) 2.99
Neural tube, skeletal and body wall defects in mice lacking transcription factor AP-2. Nature (1996) 2.98
Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development (1998) 2.90
The echinoid immune system and the phylogenetic occurrence of immune mechanisms in deuterostomes. Immunol Today (1992) 2.86
Cholesterol modification of sonic hedgehog is required for long-range signaling activity and effective modulation of signaling by Ptc1. Cell (2001) 2.84
Comparative aspects of DNA organization in Metazoa. Chromosoma (1975) 2.82
Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution. Proc Natl Acad Sci U S A (1986) 2.81
The organizer factors Chordin and Noggin are required for mouse forebrain development. Nature (2000) 2.78
A local Wnt-3a signal is required for development of the mammalian hippocampus. Development (2000) 2.75
Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature (1995) 2.73
Cis-acting regulatory sequences governing Wnt-1 expression in the developing mouse CNS. Development (1994) 2.73
Signal relay by BMP antagonism controls the SHH/FGF4 feedback loop in vertebrate limb buds. Nature (1999) 2.69
Smoothened mutants reveal redundant roles for Shh and Ihh signaling including regulation of L/R symmetry by the mouse node. Cell (2001) 2.65
Sertoli cell signaling by Desert hedgehog regulates the male germline. Curr Biol (1996) 2.59
The world according to hedgehog. Trends Genet (1997) 2.52
Studies on nucleic acid reassociation kinetics: reactivity of single-stranded tails in DNA-DNA renaturation. Proc Natl Acad Sci U S A (1975) 2.50
Schwann cell-derived Desert hedgehog controls the development of peripheral nerve sheaths. Neuron (1999) 2.50
Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development. J Clin Invest (2001) 2.49
Requirement of 19K form of Sonic hedgehog for induction of distinct ventral cell types in CNS explants. Nature (1995) 2.46
Very short repeats and coordinate induction of genes. Nature (1983) 2.44
A molecular analysis of mouse development from 8 to 10 days post coitum detects changes only in embryonic globin expression. Development (1987) 2.44
Regulation of pancreas development by hedgehog signaling. Development (2000) 2.43
Mapping of gene transcripts by nuclease protection assays and cDNA primer extension. Methods Enzymol (1987) 2.41
A measurement of the sequence complexity of polysomal messenger RNA in sea urchin embryos. Cell (1974) 2.41
Indian hedgehog coordinates endochondral bone growth and morphogenesis via parathyroid hormone related-protein-dependent and -independent pathways. Development (2000) 2.39
Differential transformation of mammary epithelial cells by Wnt genes. Mol Cell Biol (1994) 2.37
BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation. Development (2001) 2.37
Cis-regulatory logic in the endo16 gene: switching from a specification to a differentiation mode of control. Development (2001) 2.36
Structural genes adjacent to interspersed repetitive DNA sequences. Cell (1975) 2.35
Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev Biol (1985) 2.23
Combinatorial signaling by Sonic hedgehog and Wnt family members induces myogenic bHLH gene expression in the somite. Genes Dev (1995) 2.22
Expression of the FGF-related proto-oncogene int-2 during gastrulation and neurulation in the mouse. EMBO J (1988) 2.08
The zebrafish organizer requires chordino. Nature (1997) 2.06
Note on the control of gene expression during development. J Theor Biol (1971) 2.05
Multistep signaling requirements for pituitary organogenesis in vivo. Genes Dev (1998) 2.02
Sonic hedgehog regulates proliferation and inhibits differentiation of CNS precursor cells. J Neurosci (1999) 2.02