PubRank

Robert C Elston

Author PubWeight™ 204.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Optimal two-stage genotyping in population-based association studies. Genet Epidemiol 2003 6.01
2 A generalized combinatorial approach for detecting gene-by-gene and gene-by-environment interactions with application to nicotine dependence. Am J Hum Genet 2007 4.46
3 Natural selection on EPAS1 (HIF2alpha) associated with low hemoglobin concentration in Tibetan highlanders. Proc Natl Acad Sci U S A 2010 3.78
4 Improved power by use of a weighted score test for linkage disequilibrium mapping. Am J Hum Genet 2006 3.36
5 Adding further power to the Haseman and Elston method for detecting linkage in larger sibships: weighting sums and differences. Hum Hered 2003 3.33
6 Choosing an optimal method to combine P-values. Stat Med 2009 3.15
7 The genetic basis of complex traits: rare variants or "common gene, common disease"? Methods Mol Biol 2007 3.01
8 A unified association analysis approach for family and unrelated samples correcting for stratification. Am J Hum Genet 2008 3.00
9 Dissection of genomewide-scan data in extended families reveals a major locus and oligogenic susceptibility for age-related macular degeneration. Am J Hum Genet 2003 2.92
10 Detecting rare variants for complex traits using family and unrelated data. Genet Epidemiol 2010 2.80
11 Ethnic- and gender-specific association of the nicotinic acetylcholine receptor alpha4 subunit gene (CHRNA4) with nicotine dependence. Hum Mol Genet 2005 2.80
12 Premature myocardial infarction novel susceptibility locus on chromosome 1P34-36 identified by genomewide linkage analysis. Am J Hum Genet 2004 2.36
13 Linkage analysis of a complex disease through use of admixed populations. Am J Hum Genet 2004 2.21
14 Using the optimal receiver operating characteristic curve to design a predictive genetic test, exemplified with type 2 diabetes. Am J Hum Genet 2008 2.20
15 Single- and multilocus allelic variants within the GABA(B) receptor subunit 2 (GABAB2) gene are significantly associated with nicotine dependence. Am J Hum Genet 2005 2.18
16 A powerful method of combining measures of association and Hardy-Weinberg disequilibrium for fine-mapping in case-control studies. Stat Med 2006 2.18
17 Odds ratio based multifactor-dimensionality reduction method for detecting gene-gene interactions. Bioinformatics 2006 2.08
18 Whole genome scan for obstructive sleep apnea and obesity in African-American families. Am J Respir Crit Care Med 2004 2.03
19 The Family Investigation of Nephropathy and Diabetes (FIND): design and methods. J Diabetes Complications 2005 1.87
20 Self-reported race and genetic admixture. N Engl J Med 2006 1.85
21 A subset of familial colorectal neoplasia kindreds linked to chromosome 9q22.2-31.2. Proc Natl Acad Sci U S A 2003 1.84
22 The meaning of interaction. Hum Hered 2010 1.83
23 EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS Genet 2009 1.82
24 A whole-genome scan for obstructive sleep apnea and obesity. Am J Hum Genet 2002 1.81
25 Changes in human immunodeficiency virus type 1 Gag at positions L449 and P453 are linked to I50V protease mutants in vivo and cause reduction of sensitivity to amprenavir and improved viral fitness in vitro. J Virol 2002 1.80
26 Genome-wide scans for diabetic nephropathy and albuminuria in multiethnic populations: the family investigation of nephropathy and diabetes (FIND). Diabetes 2007 1.79
27 Genome-wide scan for estimated glomerular filtration rate in multi-ethnic diabetic populations: the Family Investigation of Nephropathy and Diabetes (FIND). Diabetes 2007 1.61
28 A combinatorial approach to detecting gene-gene and gene-environment interactions in family studies. Am J Hum Genet 2008 1.57
29 Improving power in contrasting linkage-disequilibrium patterns between cases and controls. Am J Hum Genet 2007 1.55
30 A whole-genome screen of a quantitative trait of age-related maculopathy in sibships from the Beaver Dam Eye Study. Am J Hum Genet 2003 1.53
31 A genome-wide scan to identify loci for smoking rate in the Framingham Heart Study population. BMC Genet 2003 1.50
32 Log-linear model-based multifactor dimensionality reduction method to detect gene gene interactions. Bioinformatics 2007 1.44
33 Genetics of the apnea hypopnea index in Caucasians and African Americans: I. Segregation analysis. Genet Epidemiol 2002 1.44
34 Detecting rare and common variants for complex traits: sibpair and odds ratio weighted sum statistics (SPWSS, ORWSS). Genet Epidemiol 2011 1.43
35 Sampling correction in linkage analysis. Genet Epidemiol 2004 1.43
36 Genome scan of M. tuberculosis infection and disease in Ugandans. PLoS One 2008 1.41
37 Plasma aldosterone is independently associated with the metabolic syndrome. Hypertension 2006 1.40
38 Are linkage analysis and the collection of family data dead? Prospects for family studies in the age of genome-wide association. Hum Hered 2007 1.39
39 Infrequent detection of germline allele-specific expression of TGFBR1 in lymphoblasts and tissues of colon cancer patients. Cancer Res 2009 1.38
40 Pleiotropic effects of a chromosome 3 locus on speech-sound disorder and reading. Am J Hum Genet 2004 1.36
41 Haplotype analysis indicates an association between the DOPA decarboxylase (DDC) gene and nicotine dependence. Hum Mol Genet 2005 1.36
42 A genomewide search finds major susceptibility loci for nicotine dependence on chromosome 10 in African Americans. Am J Hum Genet 2006 1.31
43 Heritability of the severity of diabetic retinopathy: the FIND-Eye study. Invest Ophthalmol Vis Sci 2008 1.29
44 Statistical interaction in human genetics: how should we model it if we are looking for biological interaction? Nat Rev Genet 2010 1.28
45 Two-level Haseman-Elston regression for general pedigree data analysis. Genet Epidemiol 2005 1.28
46 Identification of a major locus for age-related cortical cataract on chromosome 6p12-q12 in the Beaver Dam Eye Study. Proc Natl Acad Sci U S A 2004 1.27
47 The power of independent types of genetic information to detect association in a case-control study design. Genet Epidemiol 2008 1.24
48 Adaptive two-stage analysis of genetic association in case-control designs. Hum Hered 2007 1.23
49 CYP3A5 and ABCB1 genes influence blood pressure and response to treatment, and their effect is modified by salt. Hypertension 2007 1.23
50 Single-marker and two-marker association tests for unphased case-control genotype data, with a power comparison. Genet Epidemiol 2010 1.22
51 A partial least-square approach for modeling gene-gene and gene-environment interactions when multiple markers are genotyped. Genet Epidemiol 2009 1.18
52 A sarcoidosis genetic linkage consortium: the sarcoidosis genetic analysis (SAGA) study. Sarcoidosis Vasc Diffuse Lung Dis 2005 1.18
53 Two-marker association tests yield new disease associations for coronary artery disease and hypertension. Hum Genet 2011 1.16
54 Higher offspring survival among Tibetan women with high oxygen saturation genotypes residing at 4,000 m. Proc Natl Acad Sci U S A 2004 1.16
55 Heritability analysis of cytokines as intermediate phenotypes of tuberculosis. J Infect Dis 2003 1.16
56 Regression models for linkage: issues of traits, covariates, heterogeneity, and interaction. Hum Hered 2003 1.15
57 Gene-gene interactions among CHRNA4, CHRNB2, BDNF, and NTRK2 in nicotine dependence. Biol Psychiatry 2008 1.13
58 Heritability of renal function in hypertensive families of African descent in the Seychelles (Indian Ocean). Kidney Int 2005 1.13
59 Detecting genetic interactions for quantitative traits with U-statistics. Genet Epidemiol 2011 1.13
60 The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine beta-hydroxylase activity. Am J Hum Genet 2003 1.11
61 Identification of susceptibility genes for cancer in a genome-wide scan: results from the colon neoplasia sibling study. Am J Hum Genet 2008 1.10
62 Mapping susceptibility loci for alcohol consumption using number of grams of alcohol consumed per day as a phenotype measure. BMC Genet 2003 1.10
63 In silico gene prioritization by integrating multiple data sources. PLoS One 2011 1.10
64 GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks. AIDS 2004 1.08
65 Genomewide linkage scan for diabetic renal failure and albuminuria: the FIND study. Am J Nephrol 2011 1.07
66 Haplotype-based quantitative trait mapping using a clustering algorithm. BMC Bioinformatics 2006 1.07
67 Robust asymptotic sampling theory for correlations in pedigrees. Stat Med 2003 1.07
68 Association of specific haplotypes of neurotrophic tyrosine kinase receptor 2 gene (NTRK2) with vulnerability to nicotine dependence in African-Americans and European-Americans. Biol Psychiatry 2006 1.05
69 Evidence for a major gene influence on tumor necrosis factor-alpha expression in tuberculosis: path and segregation analysis. Hum Hered 2005 1.05
70 Association of vitamin D receptor gene variants, adiposity and colon cancer. Carcinogenesis 2008 1.05
71 Linkage and association analysis of candidate genes for TB and TNFalpha cytokine expression: evidence for association with IFNGR1, IL-10, and TNF receptor 1 genes. Hum Genet 2007 1.04
72 Complement factor H and hemicentin-1 in age-related macular degeneration and renal phenotypes. Hum Mol Genet 2007 1.03
73 The distribution of long range admixture linkage disequilibrium in an African-American population. Hum Hered 2002 1.03
74 A modified revisited Haseman-Elston method to further improve power. Hum Hered 2004 1.02
75 A framework for structural equation models in general pedigrees. Hum Hered 2011 1.02
76 Structural equation model-based genome scan for the metabolic syndrome. BMC Genet 2003 1.02
77 High heritability of ambulatory blood pressure in families of East African descent. Hypertension 2005 1.02
78 A cautionary note on the use of Mendelian randomization to infer causation in observational epidemiology. Int J Epidemiol 2007 1.01
79 Fine mapping functional sites or regions from case-control data using haplotypes of multiple linked SNPs. Ann Hum Genet 2005 1.01
80 A likelihood ratio-based Mann-Whitney approach finds novel replicable joint gene action for type 2 diabetes. Genet Epidemiol 2012 1.00
81 Identification of gene-gene interactions in the presence of missing data using the multifactor dimensionality reduction method. Genet Epidemiol 2009 1.00
82 The affected-/discordant-sib-pair design can guarantee validity of multipoint model-free linkage analysis of incomplete pedigrees when there is marker-marker disequilibrium. Am J Hum Genet 2006 1.00
83 Gene, pathway and network frameworks to identify epistatic interactions of single nucleotide polymorphisms derived from GWAS data. BMC Syst Biol 2012 1.00
84 Evaluation of removable statistical interaction for binary traits. Stat Med 2012 0.99
85 Distribution and magnitude of type I error of model-based multipoint lod scores: implications for multipoint mod scores. Genet Epidemiol 2006 0.98
86 Nonparametric disequilibrium mapping of functional sites using haplotypes of multiple tightly linked single-nucleotide polymorphism markers. Genetics 2003 0.97
87 Apolipoprotein E and obstructive sleep apnea: evaluating whether a candidate gene explains a linkage peak. Genet Epidemiol 2006 0.97
88 Immunoglobulin allotypes influence IgG antibody responses to hepatitis C virus envelope proteins E1 and E2. Hum Immunol 2008 0.97
89 A non-parametric method for building predictive genetic tests on high-dimensional data. Hum Hered 2011 0.96
90 A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer. Am J Epidemiol 2007 0.96
91 Genetic markers of IgG influence the outcome of infection with hepatitis C virus. J Infect Dis 2008 0.95
92 Genome scan for loci predisposing to anxiety disorders using a novel multivariate approach: strong evidence for a chromosome 4 risk locus. Am J Hum Genet 2006 0.94
93 Genome-wide linkage scan for genes affecting longitudinal trends in systolic blood pressure. BMC Genet 2003 0.93
94 Capability of common SNPs to tag rare variants. BMC Proc 2011 0.92
95 Linkage analysis of plasma dopamine β-hydroxylase activity in families of patients with schizophrenia. Hum Genet 2011 0.92
96 Using the optimal robust receiver operating characteristic (ROC) curve for predictive genetic tests. Biometrics 2009 0.91
97 Comparison of microsatellites, single-nucleotide polymorphisms (SNPs) and composite markers derived from SNPs in linkage analysis. BMC Genet 2005 0.91
98 Heritability and intrafamilial aggregation of arterial characteristics. J Hypertens 2008 0.91
99 Examination of association with candidate genes for diabetic nephropathy in a Mexican American population. Clin J Am Soc Nephrol 2010 0.91
100 Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility. PLoS One 2013 0.91
101 A variance component based multi-marker association test using family and unrelated data. BMC Genet 2013 0.90
102 Familial correlations and heritability of maxillary midline diastema. Am J Orthod Dentofacial Orthop 2003 0.90
103 Sampling correction in pedigree analysis. Stat Appl Genet Mol Biol 2003 0.89
104 The linkage information content value of polymorphism genetic markers in model-free linkage analysis. Hum Hered 2002 0.89
105 A generalized genetic random field method for the genetic association analysis of sequencing data. Genet Epidemiol 2014 0.88
106 Genome-wide analyses demonstrate novel loci that predispose to drusen formation. Invest Ophthalmol Vis Sci 2005 0.88
107 Is TGFBR1*6A a susceptibility allele for nonsyndromic familial colorectal neoplasia? Cancer Epidemiol Biomarkers Prev 2007 0.88
108 Interrogating population structure and its impact on association tests. BMC Proc 2011 0.88
109 The effect of multiple genetic variants in predicting the risk of type 2 diabetes. BMC Proc 2009 0.87
110 Genetic association tests: a method for the joint analysis of family and case-control data. Hum Genomics 2009 0.87
111 Estimating haplotype frequencies in pooled DNA samples when there is genotyping error. BMC Genet 2005 0.87
112 Melanocortin-3 receptor gene variants in a Maori kindred with obesity and early onset type 2 diabetes. Diabetes Res Clin Pract 2002 0.86
113 A quantitative linkage score for an association study following a linkage analysis. BMC Genet 2006 0.85
114 Testing gene-environment interactions in gene-based association studies. BMC Proc 2011 0.85
115 Power of single- vs. multi-marker tests of association. Genet Epidemiol 2012 0.85
116 Tests for a disease-susceptibility locus allowing for an inbreeding coefficient (F). Genetica 2003 0.85
117 Hybridization modeling of oligonucleotide SNP arrays for accurate DNA copy number estimation. Nucleic Acids Res 2009 0.85
118 Genome-wide association studies using an adaptive two-stage analysis for a case-control design. BMC Proc 2007 0.85
119 Association of CYP3A5 genotypes with blood pressure and renal function in African families. J Hypertens 2006 0.84
120 New multivariate test for linkage, with application to pleiotropy: fuzzy Haseman-Elston. Genet Epidemiol 2003 0.84
121 Gene-gene interaction in maternal and perinatal research. J Biomed Biotechnol 2010 0.83
122 Reduction of sample heterogeneity through use of population substructure: an example from a population of African American families with sarcoidosis. Am J Hum Genet 2006 0.83
123 Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances. Am J Med Genet B Neuropsychiatr Genet 2012 0.83
124 X-linked extension of the revised Haseman-Elston algorithm for linkage analysis in sib pairs. Hum Hered 2003 0.83
125 The null distribution of likelihood-ratio statistics in the conditional-logistic linkage model. Front Genet 2013 0.82
126 Using linkage and association to identify and model genetic effects: summary of GAW15 Group 4. Genet Epidemiol 2007 0.82
127 Improvement of mapping accuracy by unifying linkage and association analysis. Genetics 2005 0.82
128 PedWiz: a web-based tool for pedigree informatics. Front Genet 2013 0.81
129 A locus for generalized tonic-clonic seizure susceptibility maps to chromosome 10q25-q26. Ann Neurol 2005 0.81
130 Linkage analysis of alcohol dependence using both affected and discordant sib pairs. BMC Genet 2005 0.81
131 Prediction of empirical p values from asymptotic p values for conditional logistic affected relative pair linkage analysis. Hum Hered 2006 0.81
132 A genome-wide linkage scan identifies multiple quantitative trait loci for HDL-cholesterol levels in families with premature CAD and MI. J Lipid Res 2010 0.81
133 A method to detect single-nucleotide polymorphisms accounting for a linkage signal using covariate-based affected relative pair linkage analysis. BMC Proc 2011 0.81
134 Genetic linkage of prostate cancer risk to the chromosome 3 region bearing FHIT. Cancer Res 2005 0.80
135 A novel method to detect rare variants using both family and unrelated case-control data. BMC Proc 2011 0.80
136 Will formal genetics become dispensable? Hum Hered 2013 0.79
137 Evaluation of a LASSO regression approach on the unrelated samples of Genetic Analysis Workshop 17. BMC Proc 2011 0.79
138 Estimating heritability using family and unrelated individuals data. BMC Proc 2011 0.79
139 Increase in power of transmission-disequilibrium tests for quantitative traits. Genet Epidemiol 2002 0.79
140 A novel approach to detect parent-of-origin effects from pedigree data with application to Beckwith-Wiedemann syndrome. Ann Hum Genet 2007 0.79
141 Heritability estimation for speech-sound traits with developmental trajectories. Behav Genet 2010 0.79
142 The bias introduced by population stratification in IBD based linkage analysis. Hum Hered 2005 0.79
143 Linkage studies of catechol-O-methyltransferase (COMT) and dopamine-beta-hydroxylase (DBH) cDNA expression levels. BMC Proc 2007 0.79
144 Association of ABCB1 genetic variants with renal function in Africans and in Caucasians. BMC Med Genomics 2008 0.78
145 Linkage-disequilibrium-based binning misleads the interpretation of genome-wide association studies. Am J Hum Genet 2012 0.78
146 Linkage mapping methods applied to the COGA data set: presentation Group 4 of Genetic Analysis Workshop 14. Genet Epidemiol 2005 0.78
147 Tapasin gene polymorphism in systemic onset juvenile rheumatoid arthritis: a family-based case-control study. Arthritis Res Ther 2005 0.78
148 Two-stage analysis strategy for identifying the IgM quantitative trait locus. BMC Proc 2007 0.78
149 Genetic characterization and fine mapping of susceptibility loci for sarcoidosis in African Americans on chromosome 5. Hum Genet 2006 0.78
150 Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions. BMC Genet 2005 0.78
151 Enhancing the power to detect low-frequency variants in genome-wide screens. Genetics 2014 0.77
152 A method to correct for population structure using a segregation model. BMC Proc 2009 0.77
153 Bagging optimal ROC curve method for predictive genetic tests, with an application for rheumatoid arthritis. J Biopharm Stat 2010 0.77
154 Haseman-Elston weighted by marker informativity. BMC Genet 2005 0.76
155 Phase uncertainty in case-control association studies. Genet Epidemiol 2009 0.76
156 Comparison of a unified analysis approach for family and unrelated samples with the transmission-disequilibrium test to study associations of hypertension in the Framingham Heart Study. BMC Proc 2009 0.76
157 Paternal age effect on age of onset in bipolar I disorder is mediated by sex and family history. Am J Med Genet B Neuropsychiatr Genet 2012 0.76
158 Extension of the Haseman-Elston regression model to longitudinal data. Hum Hered 2006 0.76
159 Familial aggregation of allergen-specific sensitization and asthma. Pediatr Allergy Immunol 2011 0.76
160 Prospects of admixture linkage disequilibrium mapping in the African-American genome. Cytometry 2002 0.75
161 Optimizing the evidence for linkage by permuting marker order. BMC Genet 2005 0.75
162 Program update and novel use of the DESPAIR program to design a genome-wide linkage study using relative pairs. Hum Hered 2009 0.75
163 Comparison of sarcoidosis phenotypes among affected African-American siblings. Chest 2006 0.75
164 Fine-mapping using the weighted average method for a case-control study. BMC Genet 2005 0.75
165 Modeling Genetic and Environmental Factors in Biological Systems Using Structural Equation Modeling: An Application to Energy Balance. Proc Ohio Collab Conf Bioinform 2009 0.75
166 A logistic mixture model for a family-based association study. BMC Proc 2007 0.75
167 Response to Epstein et al. Am J Hum Genet 2002 0.75
168 Bayesian intervals for linkage locations. Genet Epidemiol 2009 0.75
169 Treatment of uninformative families in mean allele sharing tests for linkage. Stat Appl Genet Mol Biol 2006 0.75
170 Correcting for ascertainment. Methods Mol Biol 2012 0.75
171 A polymorphism (D20S32e) close to the human melanocortin receptor 3 is associated with insulin resistance but not the metabolic syndrome. Diabetes Res Clin Pract 2008 0.75
172 Effect of linkage disequilibrium between markers in linkage and association analyses. Genet Epidemiol 2007 0.75
173 Model-free tests for genetic linkage. Curr Protoc Hum Genet 2012 0.75
174 Parametric linkage analysis. Methods Mol Biol 2002 0.75