Published in Br J Cancer on May 29, 2007
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition. Oncogene (2010) 1.99
Hyperglycemia, insulin resistance, impaired pancreatic β-cell function, and risk of pancreatic cancer. J Natl Cancer Inst (2013) 1.80
Diabetes and pancreatic cancer. Mol Carcinog (2012) 1.71
Mechanisms of obesity-induced gastrointestinal neoplasia. Gastroenterology (2013) 1.18
Serum IGF-I, IGF-II, IGFBP-3, and IGF-I/IGFBP-3 molar ratio and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial. Cancer Epidemiol Biomarkers Prev (2010) 1.07
An overview of genetic polymorphisms and pancreatic cancer risk in molecular epidemiologic studies. J Epidemiol (2010) 0.99
Effect of insulin-like growth factor gene polymorphisms alone or in interaction with diabetes on the risk of pancreatic cancer. Cancer Epidemiol Biomarkers Prev (2008) 0.97
Glycemic index, carbohydrates, glycemic load, and the risk of pancreatic cancer in a prospective cohort study. Cancer Epidemiol Biomarkers Prev (2009) 0.94
Soft drink and juice consumption and risk of pancreatic cancer: the Singapore Chinese Health Study. Cancer Epidemiol Biomarkers Prev (2010) 0.91
Concentrations of IGF-I and IGFBP-3 and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition. Br J Cancer (2012) 0.85
Association between somatostatin receptor 5 gene polymorphisms and pancreatic cancer risk and survival. Cancer (2011) 0.81
Epidemiology and Inherited Predisposition for Sporadic Pancreatic Adenocarcinoma. Hematol Oncol Clin North Am (2015) 0.77
Understanding the Key to Targeting the IGF Axis in Cancer: A Biomarker Assessment. Front Oncol (2015) 0.76
IGF-I and IGFBP-3 before and after inpatient alcohol detoxification in alcohol-dependent subjects. Med Sci Monit (2011) 0.75
Serum Insulin-Like Growth Factor Axis and the Risk of Pancreatic Cancer: Systematic Review and Meta-Analysis. Nutrients (2017) 0.75
Pancreatic cancer. Lancet (2004) 11.63
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet (1998) 10.11
Insulin-like growth factors and their binding proteins: biological actions. Endocr Rev (1995) 9.54
Insulin-like growth factor (IGF)-I, IGF binding protein-3, and cancer risk: systematic review and meta-regression analysis. Lancet (2004) 8.77
Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science (2003) 6.85
Fasting serum glucose level and cancer risk in Korean men and women. JAMA (2005) 6.69
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science (1998) 6.50
Test of the National Death Index and Equifax Nationwide Death Search. Am J Epidemiol (1994) 6.47
Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev (2002) 6.43
Type-II diabetes and pancreatic cancer: a meta-analysis of 36 studies. Br J Cancer (2005) 6.06
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst (1999) 5.27
Physical activity, obesity, height, and the risk of pancreatic cancer. JAMA (2001) 4.30
Abnormal glucose metabolism and pancreatic cancer mortality. JAMA (2000) 4.01
Serum C-peptide, insulin-like growth factor (IGF)-I, IGF-binding proteins, and colorectal cancer risk in women. J Natl Cancer Inst (2000) 3.57
Prevention of pancreatic cancer induction in hamsters by metformin. Gastroenterology (2001) 3.38
The epigenetics of cancer etiology. Semin Cancer Biol (2004) 3.24
The effects of insulin-like growth factors on tumorigenesis and neoplastic growth. Endocr Rev (2000) 3.01
Loss of imprinting of Igf2 alters intestinal maturation and tumorigenesis in mice. Science (2005) 2.72
Insulin, glucose, insulin resistance, and pancreatic cancer in male smokers. JAMA (2005) 2.71
Energy balance and cancer: the role of insulin and insulin-like growth factor-I. Proc Nutr Soc (2001) 2.68
Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism. J Biol Chem (1997) 2.44
A prospective study of cigarette smoking and the risk of pancreatic cancer. Arch Intern Med (1996) 2.31
A prospective study of C-peptide, insulin-like growth factor-I, insulin-like growth factor binding protein-1, and the risk of colorectal cancer in women. Cancer Epidemiol Biomarkers Prev (2005) 2.15
Epidemiology of insulin-like growth factor-I in elderly men and women. The Rancho Bernardo Study. Am J Epidemiol (1997) 2.06
Insulin-like growth factor I overexpression in human pancreatic cancer: evidence for autocrine and paracrine roles. Cancer Res (1995) 1.89
Nutrition, insulin, insulin-like growth factors and cancer. Horm Metab Res (2004) 1.84
Overall obesity, abdominal adiposity, diabetes and cigarette smoking in relation to the risk of pancreatic cancer in two Swedish population-based cohorts. Br J Cancer (2005) 1.71
Insulin promotes pancreatic cancer: evidence for endocrine influence on exocrine pancreatic tumors. J Surg Res (1996) 1.69
Regulation of hypoxia-inducible factor-1alpha, vascular endothelial growth factor, and angiogenesis by an insulin-like growth factor-I receptor autocrine loop in human pancreatic cancer. Am J Pathol (2003) 1.45
Insulin-like growth factor I and transforming growth factor alpha as autocrine growth factors in human pancreatic cancer cell growth. Cancer Res (1990) 1.38
Dietary sugar, glycemic load, and pancreatic cancer risk in a prospective study. J Natl Cancer Inst (2002) 1.35
Physiological concentrations of insulin augment pancreatic cancer cell proliferation and glucose utilization by activating MAP kinase, PI3 kinase and enhancing GLUT-1 expression. Pancreas (2000) 1.33
Racial variation in insulin-like growth factor-1 and binding protein-3 concentrations in middle-aged men. Cancer Epidemiol Biomarkers Prev (1999) 1.30
Anthropometric factors and pancreatic cancer in a population-based case-control study in the San Francisco Bay area. Cancer Causes Control (2005) 1.17
Deregulation of the IGF axis in cancer: epidemiological evidence and potential therapeutic interventions. Endocr Relat Cancer (2003) 1.14
On the role of the islets of Langerhans in pancreatic cancer. Histol Histopathol (2004) 1.10
Serum insulin-like growth factor-I, insulin-like growth factor binding protein-3, and the risk of pancreatic cancer death. Int J Cancer (2004) 1.10
In vitro influences between pancreatic adenocarcinoma cells and pancreatic islets. J Surg Res (1998) 1.04
Requirement of different signaling pathways mediated by insulin-like growth factor-I receptor for proliferation, invasion, and VPF/VEGF expression in a pancreatic carcinoma cell line. Biochem Biophys Res Commun (2003) 1.02
Insulin-like growth factor (IGF)-1, IGF-binding protein-3, and pancreatic cancer in male smokers. Cancer Epidemiol Biomarkers Prev (2004) 1.00
Role of insulin receptor substrates and protein kinase C-zeta in vascular permeability factor/vascular endothelial growth factor expression in pancreatic cancer cells. J Biol Chem (2003) 0.90
Influence of diabetes on susceptibility to experimental pancreatic cancer. Am J Surg (1988) 0.88
Growth inhibition by insulin-like growth factor (IGF) binding protein-3--what's IGF got to do with it? Endocrinology (1997) 0.83
CHARMM: the biomolecular simulation program. J Comput Chem (2009) 27.71
Reproducibility and validity of a semiquantitative food frequency questionnaire. Am J Epidemiol (1985) 26.13
Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med (1997) 18.85
An STS-based map of the human genome. Science (1995) 17.72
Reproducibility and validity of an expanded self-administered semiquantitative food frequency questionnaire among male health professionals. Am J Epidemiol (1992) 17.17
GAL4-VP16 is an unusually potent transcriptional activator. Nature (1988) 16.53
Total energy intake: implications for epidemiologic analyses. Am J Epidemiol (1986) 16.34
C-reactive protein, interleukin 6, and risk of developing type 2 diabetes mellitus. JAMA (2001) 15.85
Diet, lifestyle, and the risk of type 2 diabetes mellitus in women. N Engl J Med (2001) 14.48
A gene map of the human genome. Science (1996) 14.32
Deletion analysis of GAL4 defines two transcriptional activating segments. Cell (1987) 14.13
A physical map of 30,000 human genes. Science (1998) 12.43
Design and serendipity in establishing a large cohort with wide dietary intake distributions : the National Institutes of Health-American Association of Retired Persons Diet and Health Study. Am J Epidemiol (2001) 11.17
The use of estrogens and progestins and the risk of breast cancer in postmenopausal women. N Engl J Med (1995) 11.08
Body weight and mortality among women. N Engl J Med (1995) 11.04
Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption. Int J Epidemiol (1989) 10.98
Validation of questionnaire information on risk factors and disease outcomes in a prospective cohort study of women. Am J Epidemiol (1986) 10.84
Validity of self-reported waist and hip circumferences in men and women. Epidemiology (1990) 10.57
Circulating concentrations of insulin-like growth factor-I and risk of breast cancer. Lancet (1998) 10.11
Reproducibility and validity of a self-administered physical activity questionnaire. Int J Epidemiol (1994) 9.90
Reproducibility and validity of food intake measurements from a semiquantitative food frequency questionnaire. J Am Diet Assoc (1993) 9.90
Highly pathogenic H5N1 influenza virus infection in migratory birds. Science (2005) 9.64
Aspirin and the risk of colorectal cancer in women. N Engl J Med (1995) 9.59
Dietary fat and coronary heart disease: a comparison of approaches for adjusting for total energy intake and modeling repeated dietary measurements. Am J Epidemiol (1999) 9.34
Intravenous and intracoronary fibrinolytic therapy in acute myocardial infarction: overview of results on mortality, reinfarction and side-effects from 33 randomized controlled trials. Eur Heart J (1985) 9.28
Expression cloning of a cDNA encoding a retinoblastoma-binding protein with E2F-like properties. Cell (1992) 9.19
The genome of the social amoeba Dictyostelium discoideum. Nature (2005) 9.18
Primary prevention of coronary heart disease in women through diet and lifestyle. N Engl J Med (2000) 9.05
Relation of meat, fat, and fiber intake to the risk of colon cancer in a prospective study among women. N Engl J Med (1990) 8.98
Postmenopausal estrogen therapy and cardiovascular disease. Ten-year follow-up from the nurses' health study. N Engl J Med (1991) 8.66
Prospective study of alcohol consumption and risk of coronary disease in men. Lancet (1991) 8.64
Annual deaths attributable to obesity in the United States. JAMA (1999) 8.62
A prospective evaluation of plasma prostate-specific antigen for detection of prostatic cancer. JAMA (1995) 8.60
Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. N Engl J Med (1996) 8.57
Test of the National Death Index. Am J Epidemiol (1984) 8.46
Dietary fat intake and the risk of coronary heart disease in women. N Engl J Med (1997) 8.43
Plasma concentration of interleukin-6 and the risk of future myocardial infarction among apparently healthy men. Circulation (2000) 8.17
The Nurses' Health Study: 20-year contribution to the understanding of health among women. J Womens Health (1997) 8.00
Physical activity and incidence of non-insulin-dependent diabetes mellitus in women. Lancet (1991) 7.87
Weight gain as a risk factor for clinical diabetes mellitus in women. Ann Intern Med (1995) 7.62
Obesity, fat distribution, and weight gain as risk factors for clinical diabetes in men. Diabetes Care (1994) 7.11
Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. JAMA (1998) 7.09
Reproducibility and validity of dietary patterns assessed with a food-frequency questionnaire. Am J Clin Nutr (1999) 7.02
Plasma organochlorine levels and the risk of breast cancer. N Engl J Med (1997) 7.02
Dietary fiber, glycemic load, and risk of non-insulin-dependent diabetes mellitus in women. JAMA (1997) 6.92
Plasma insulin-like growth factor-I and prostate cancer risk: a prospective study. Science (1998) 6.50
Test of the National Death Index and Equifax Nationwide Death Search. Am J Epidemiol (1994) 6.47
The effect of fruit and vegetable intake on risk for coronary heart disease. Ann Intern Med (2001) 6.37
Vitamin E consumption and the risk of coronary heart disease in men. N Engl J Med (1993) 6.37
Physical activity and television watching in relation to risk for type 2 diabetes mellitus in men. Arch Intern Med (2001) 6.23
Abdominal adiposity and coronary heart disease in women. JAMA (1998) 6.21
Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med (1999) 6.17
A prospective study of family history and the risk of colorectal cancer. N Engl J Med (1994) 6.12
A prospective study of obesity and risk of coronary heart disease in women. N Engl J Med (1990) 6.06
Cost-effectiveness of screening for colorectal cancer in the general population. JAMA (2000) 5.88
A prospective study of dietary calcium and other nutrients and the risk of symptomatic kidney stones. N Engl J Med (1993) 5.87
Triggering of sudden death from cardiac causes by vigorous exertion. N Engl J Med (2000) 5.63
The assessment of alcohol consumption by a simple self-administered questionnaire. Am J Epidemiol (1991) 5.60
Physical activity, obesity, and risk for colon cancer and adenoma in men. Ann Intern Med (1995) 5.42
Aspirin use and the risk for colorectal cancer and adenoma in male health professionals. Ann Intern Med (1994) 5.42
Vitamin E consumption and the risk of coronary disease in women. N Engl J Med (1993) 5.39
The use of a self-administered questionnaire to assess diet four years in the past. Am J Epidemiol (1988) 5.32
Tubal ligation, hysterectomy, and risk of ovarian cancer. A prospective study. JAMA (1993) 5.31
Prospective study of colorectal cancer risk in men and plasma levels of insulin-like growth factor (IGF)-I and IGF-binding protein-3. J Natl Cancer Inst (1999) 5.27
A prospective, observational study of postmenopausal hormone therapy and primary prevention of cardiovascular disease. Ann Intern Med (2000) 5.17
Prospective study of major dietary patterns and risk of coronary heart disease in men. Am J Clin Nutr (2000) 5.17
A prospective cohort study of vasectomy and prostate cancer in US men. JAMA (1993) 5.09
Birthweight as a risk factor for breast cancer. Lancet (1996) 5.05
Intake of trans fatty acids and risk of coronary heart disease among women. Lancet (1993) 5.00
Postmenopausal hormone therapy and mortality. N Engl J Med (1997) 4.96
A prospective evaluation of an angiotensin-converting-enzyme gene polymorphism and the risk of ischemic heart disease. N Engl J Med (1995) 4.94
Variation in the incidence of uterine leiomyoma among premenopausal women by age and race. Obstet Gynecol (1997) 4.84
Dual effects of weight and weight gain on breast cancer risk. JAMA (1997) 4.81
Dietary fat and fiber in relation to risk of breast cancer. An 8-year follow-up. JAMA (1992) 4.80
Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range. JAMA (1995) 4.78
Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood (1997) 4.78
Plasma sex steroid hormone levels and risk of breast cancer in postmenopausal women. J Natl Cancer Inst (1998) 4.74
Menopause and the risk of coronary heart disease in women. N Engl J Med (1987) 4.70
Prospective study of sex hormone levels and risk of prostate cancer. J Natl Cancer Inst (1996) 4.66