Published in Protein Cell on July 12, 2011
Hydrogen peroxide sensing, signaling and regulation of transcription factors. Redox Biol (2014) 1.54
Quantitative Proteomic Atlas of Ubiquitination and Acetylation in the DNA Damage Response. Mol Cell (2015) 1.12
Inhibition of AMP-activated protein kinase α (AMPKα) by doxorubicin accentuates genotoxic stress and cell death in mouse embryonic fibroblasts and cardiomyocytes: role of p53 and SIRT1. J Biol Chem (2012) 1.08
Emerging beneficial roles of sirtuins in heart failure. Basic Res Cardiol (2012) 1.08
p53 N-terminal phosphorylation: a defining layer of complex regulation. Carcinogenesis (2012) 1.06
c-Jun N-terminal kinase 1/c-Jun activation of the p53/microRNA 34a/sirtuin 1 pathway contributes to apoptosis induced by deoxycholic acid in rat liver. Mol Cell Biol (2014) 1.06
p53-mediated heterochromatin reorganization regulates its cell fate decisions. Nat Struct Mol Biol (2012) 1.00
NORE1A is a Ras senescence effector that controls the apoptotic/senescent balance of p53 via HIPK2. J Cell Biol (2015) 0.99
hSSB1 regulates both the stability and the transcriptional activity of p53. Cell Res (2012) 0.97
p53 Acetylation: Regulation and Consequences. Cancers (Basel) (2014) 0.97
BRD4 associates with p53 in DNMT3A-mutated leukemia cells and is implicated in apoptosis by the bromodomain inhibitor JQ1. Cancer Med (2013) 0.96
Transcription, epigenetics and ameliorative strategies in Huntington's Disease: a genome-wide perspective. Mol Neurobiol (2014) 0.96
Sulforaphane induction of p21(Cip1) cyclin-dependent kinase inhibitor expression requires p53 and Sp1 transcription factors and is p53-dependent. J Biol Chem (2012) 0.94
Acetylation dynamics of human nuclear proteins during the ionizing radiation-induced DNA damage response. Cell Cycle (2013) 0.93
Assembly and interrogation of Alzheimer's disease genetic networks reveal novel regulators of progression. PLoS One (2015) 0.92
MDM4/HIPK2/p53 cytoplasmic assembly uncovers coordinated repression of molecules with anti-apoptotic activity during early DNA damage response. Oncogene (2015) 0.89
Human cytomegalovirus pUL29/28 and pUL38 repression of p53-regulated p21CIP1 and caspase 1 promoters during infection. J Virol (2012) 0.89
The multifunctional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell-cycle arrest. Cell Rep (2014) 0.89
Class I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response. FASEB J (2012) 0.88
Nonenzymatic Protein Acetylation Detected by NAPPA Protein Arrays. ACS Chem Biol (2015) 0.87
Ginsenoside Rg3 inhibits melanoma cell proliferation through down-regulation of histone deacetylase 3 (HDAC3) and increase of p53 acetylation. PLoS One (2014) 0.87
Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells. Int J Cancer (2012) 0.86
Extensive post-translational modification of active and inactivated forms of endogenous p53. Mol Cell Proteomics (2013) 0.86
TRIM25 has a dual function in the p53/Mdm2 circuit. Oncogene (2015) 0.84
Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones. Leuk Res Rep (2012) 0.83
Combined HDAC1 and HDAC2 Depletion Promotes Retinal Ganglion Cell Survival After Injury Through Reduction of p53 Target Gene Expression. ASN Neuro (2015) 0.83
Acetylation of p53 stimulates miRNA processing and determines cell survival following genotoxic stress. EMBO J (2013) 0.82
NADPH oxidases: key modulators in aging and age-related cardiovascular diseases? Clin Sci (Lond) (2016) 0.82
Modulation of macrophage activities in proliferation, lysosome, and phagosome by the nonspecific immunostimulator, mica. PLoS One (2015) 0.82
Aberrant protein S-nitrosylation contributes to the pathophysiology of neurodegenerative diseases. Neurobiol Dis (2015) 0.82
Acetylation of drosha on the N-terminus inhibits its degradation by ubiquitination. PLoS One (2013) 0.81
SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence. Nat Commun (2016) 0.80
β-Catenin C-terminal signals suppress p53 and are essential for artery formation. Nat Commun (2016) 0.80
Mechanisms of Histone Deacetylase Inhibitor-Regulated Gene Expression in Cancer Cells. Antioxid Redox Signal (2014) 0.80
Augmentation of NAD(+) by NQO1 attenuates cisplatin-mediated hearing impairment. Cell Death Dis (2014) 0.79
Oridonin, a novel lysine acetyltransferases inhibitor, inhibits proliferation and induces apoptosis in gastric cancer cells through p53- and caspase-3-mediated mechanisms. Oncotarget (2016) 0.79
Functional analysis of the acetylation of human p53 in DNA damage responses. Protein Cell (2014) 0.79
New Therapeutic Concept of NAD Redox Balance for Cisplatin Nephrotoxicity. Biomed Res Int (2016) 0.79
Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium. Development (2015) 0.79
Effects of ethylene glycol monomethyl ether and its metabolite, 2-methoxyacetic acid, on organogenesis stage mouse limbs in vitro. Birth Defects Res B Dev Reprod Toxicol (2014) 0.79
Regain control of p53: Targeting leukemia stem cells by isoform-specific HDAC inhibition. Exp Hematol (2016) 0.79
Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer. Front Oncol (2015) 0.79
NAD(+) Metabolism in Age-Related Hearing Loss. Aging Dis (2014) 0.79
SIRT3 in Cardiac Physiology and Disease. Front Cardiovasc Med (2016) 0.78
USP7 Enforces Heterochromatinization of p53 Target Promoters by Protecting SUV39H1 from MDM2-Mediated Degradation. Cell Rep (2016) 0.78
Atypical ubiquitin ligase RNF31: the nuclear factor modulator in breast cancer progression. BMC Cancer (2016) 0.78
Histone modifications: Targeting head and neck cancer stem cells. World J Stem Cells (2014) 0.78
Histone H3 Acetyl K9 and Histone H3 Tri Methyl K4 as Prognostic Markers for Patients with Cervical Cancer. Int J Mol Sci (2017) 0.78
Histones: Controlling Tumor Signaling Circuitry. J Carcinog Mutagen (2013) 0.77
Loss of BRG1 induces CRC cell senescence by regulating p53/p21 pathway. Cell Death Dis (2017) 0.77
Ischemic preconditioning, retinal neuroprotection and histone deacetylase activities. Exp Eye Res (2016) 0.77
Acetylation of HDAC1 and degradation of SIRT1 form a positive feedback loop to regulate p53 acetylation during heat-shock stress. Cell Death Dis (2015) 0.76
Insights into Lysine Deacetylation of Natively Folded Substrate Proteins by Sirtuins. J Biol Chem (2016) 0.76
Analysis of TRRAP as a Potential Molecular Marker and Therapeutic Target for Breast Cancer. J Breast Cancer (2016) 0.76
FGF8, c-Abl and p300 participate in a pathway that controls stability and function of the ΔNp63α protein. Hum Mol Genet (2015) 0.76
Activation of p53 in Down Syndrome and in the Ts65Dn Mouse Brain is Associated with a Pro-Apoptotic Phenotype. J Alzheimers Dis (2016) 0.76
Impact of the adenoviral E4 Orf3 protein on the activity and posttranslational modification of p53. J Virol (2015) 0.76
The p53-HAT connection: PCAF rules? Cell Cycle (2012) 0.75
Proteomics insights into DNA damage response and translating this knowledge to clinical strategies. Proteomics (2016) 0.75
The ubiquitin ligase LIN41/TRIM71 targets p53 to antagonize cell death and differentiation pathways during stem cell differentiation. Cell Death Differ (2017) 0.75
The novel p53 target TNFAIP8 variant 2 is increased in cancer and offsets p53-dependent tumor suppression. Cell Death Differ (2016) 0.75
Molecular mechanisms of OLIG2 transcription factor in brain cancer. Oncotarget (2016) 0.75
Post transcriptional control of the epigenetic stem cell regulator PLZF by sirtuin and HDAC deacetylases. Epigenetics Chromatin (2015) 0.75
Combining p53 stabilizers with metformin induces synergistic apoptosis through regulation of energy metabolism in castration-resistant prostate cancer. Cell Cycle (2016) 0.75
Transcriptional regulatory code of a eukaryotic genome. Nature (2004) 27.21
Lysine acetylation targets protein complexes and co-regulates major cellular functions. Science (2009) 20.49
Combinatorial patterns of histone acetylations and methylations in the human genome. Nat Genet (2008) 18.28
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell (1997) 16.79
hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. Cell (2001) 15.97
Negative control of p53 by Sir2alpha promotes cell survival under stress. Cell (2001) 15.05
Substrate and functional diversity of lysine acetylation revealed by a proteomics survey. Mol Cell (2006) 11.38
Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J (2003) 11.27
CBP/p300 in cell growth, transformation, and development. Genes Dev (2000) 10.76
DNA damage-induced phosphorylation of p53 alleviates inhibition by MDM2. Cell (1997) 10.52
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature (1995) 10.18
p53 mutant mice that display early ageing-associated phenotypes. Nature (2002) 10.05
Modes of p53 regulation. Cell (2009) 9.31
Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A (2003) 9.14
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature (1995) 8.68
The first 30 years of p53: growing ever more complex. Nat Rev Cancer (2009) 8.00
DNA damage activates p53 through a phosphorylation-acetylation cascade. Genes Dev (1998) 7.78
Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. Cell (2005) 6.86
Calorie restriction, SIRT1 and metabolism: understanding longevity. Nat Rev Mol Cell Biol (2005) 6.34
Acetylation is indispensable for p53 activation. Cell (2008) 5.70
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell (2006) 5.64
p53 ubiquitination: Mdm2 and beyond. Mol Cell (2006) 5.57
Post-translational modifications and activation of p53 by genotoxic stresses. Eur J Biochem (2001) 5.43
Acetylation of the p53 DNA-binding domain regulates apoptosis induction. Mol Cell (2006) 5.40
Impaired DNA damage response, genome instability, and tumorigenesis in SIRT1 mutant mice. Cancer Cell (2008) 5.11
The ubiquitin ligase COP1 is a critical negative regulator of p53. Nature (2004) 5.05
Pirh2, a p53-induced ubiquitin-protein ligase, promotes p53 degradation. Cell (2003) 4.96
Deacetylation of p53 modulates its effect on cell growth and apoptosis. Nature (2000) 4.93
p53 sites acetylated in vitro by PCAF and p300 are acetylated in vivo in response to DNA damage. Mol Cell Biol (1999) 4.88
The INK4a/ARF network in tumour suppression. Nat Rev Mol Cell Biol (2001) 4.83
Acetylation of p53 activates transcription through recruitment of coactivators/histone acetyltransferases. Mol Cell (2001) 4.73
DBC1 is a negative regulator of SIRT1. Nature (2008) 4.66
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell (2005) 4.60
Negative regulation of the deacetylase SIRT1 by DBC1. Nature (2008) 4.29
Acetylation of p53 inhibits its ubiquitination by Mdm2. J Biol Chem (2002) 3.37
p300/CBP-mediated p53 acetylation is commonly induced by p53-activating agents and inhibited by MDM2. EMBO J (2001) 3.37
Polyubiquitination of p53 by a ubiquitin ligase activity of p300. Science (2003) 3.21
Mammalian SIRT1 limits replicative life span in response to chronic genotoxic stress. Cell Metab (2005) 3.15
p300/CBP and cancer. Oncogene (2004) 3.13
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc Natl Acad Sci U S A (2004) 3.06
Telomeres, stem cells, senescence, and cancer. J Clin Invest (2004) 2.87
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation. Mol Cell Biol (2000) 2.72
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol (2005) 2.72
SIRT1 regulates the function of the Nijmegen breakage syndrome protein. Mol Cell (2007) 2.42
Targeted inactivation of Mdm2 RING finger E3 ubiquitin ligase activity in the mouse reveals mechanistic insights into p53 regulation. Cancer Cell (2007) 2.42
The C-terminal lysines fine-tune P53 stress responses in a mouse model but are not required for stability control or transactivation. Proc Natl Acad Sci U S A (2005) 2.40
Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell (2006) 2.32
Structure of the 53BP1 BRCT region bound to p53 and its comparison to the Brca1 BRCT structure. Genes Dev (2002) 2.26
Distinct p53 acetylation cassettes differentially influence gene-expression patterns and cell fate. J Cell Biol (2006) 2.21
Acetylation of p53 at lysine 373/382 by the histone deacetylase inhibitor depsipeptide induces expression of p21(Waf1/Cip1). Mol Cell Biol (2006) 2.02
ASPP: a new family of oncogenes and tumour suppressor genes. Br J Cancer (2007) 1.94
SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. PLoS One (2008) 1.58
CBP and p300 are cytoplasmic E4 polyubiquitin ligases for p53. Proc Natl Acad Sci U S A (2009) 1.53
An acetylation switch in p53 mediates holo-TFIID recruitment. Mol Cell (2007) 1.48
Acetylation of mouse p53 at lysine 317 negatively regulates p53 apoptotic activities after DNA damage. Mol Cell Biol (2006) 1.45
SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol Cell (2010) 1.41
Identification and characterization of a novel p300-mediated p53 acetylation site, lysine 305. J Biol Chem (2003) 1.28
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation. J Biol Chem (2008) 1.27
Inhibition of p53 degradation by Mdm2 acetylation. FEBS Lett (2004) 1.24
Histone acetylation: where to go and how to get there. Epigenetics (2009) 1.21
MSL2 promotes Mdm2-independent cytoplasmic localization of p53. J Biol Chem (2008) 1.21
Lessons from interconnected ubiquitylation and acetylation of p53: think metastable networks. Biochem Soc Trans (2010) 1.02
The ARF/oncogene pathway activates p53 acetylation within the DNA binding domain. Cell Cycle (2007) 0.92
Modes of p53 regulation. Cell (2009) 9.31
Mammalian SIRT1 represses forkhead transcription factors. Cell (2004) 8.89
Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization. Nature (2002) 7.71
Acetylation is indispensable for p53 activation. Cell (2008) 5.70
Tip60-dependent acetylation of p53 modulates the decision between cell-cycle arrest and apoptosis. Mol Cell (2006) 5.64
p53 ubiquitination: Mdm2 and beyond. Mol Cell (2006) 5.57
Ubiquitination, phosphorylation and acetylation: the molecular basis for p53 regulation. Curr Opin Cell Biol (2003) 5.46
SIRT1 transgenic mice show phenotypes resembling calorie restriction. Aging Cell (2007) 5.30
Mono- versus polyubiquitination: differential control of p53 fate by Mdm2. Science (2003) 5.23
Tumor suppressor HIC1 directly regulates SIRT1 to modulate p53-dependent DNA-damage responses. Cell (2005) 5.04
Tumor suppression in the absence of p53-mediated cell-cycle arrest, apoptosis, and senescence. Cell (2012) 4.96
SirT1 gain of function increases energy efficiency and prevents diabetes in mice. Cell Metab (2008) 4.89
ARF-BP1/Mule is a critical mediator of the ARF tumor suppressor. Cell (2005) 4.60
Non-transcriptional control of DNA replication by c-Myc. Nature (2007) 4.55
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde. Cell (2002) 4.33
Negative regulation of the deacetylase SIRT1 by DBC1. Nature (2008) 4.29
FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metab (2005) 4.14
A dynamic role of HAUSP in the p53-Mdm2 pathway. Mol Cell (2004) 4.05
Acetylation of p53 inhibits its ubiquitination by Mdm2. J Biol Chem (2002) 3.37
How does SIRT1 affect metabolism, senescence and cancer? Nat Rev Cancer (2008) 3.17
Non-invasive prenatal measurement of the fetal genome. Nature (2012) 3.11
Lysine propionylation and butyrylation are novel post-translational modifications in histones. Mol Cell Proteomics (2007) 3.09
Acetylation of p53 augments its site-specific DNA binding both in vitro and in vivo. Proc Natl Acad Sci U S A (2004) 3.06
Parc: a cytoplasmic anchor for p53. Cell (2003) 3.06
Acetylation inactivates the transcriptional repressor BCL6. Nat Genet (2002) 3.00
Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage. Nat Cell Biol (2006) 2.85
Functional analysis of the roles of posttranslational modifications at the p53 C terminus in regulating p53 stability and activity. Mol Cell Biol (2005) 2.72
A local mechanism mediates NAD-dependent protection of axon degeneration. J Cell Biol (2005) 2.64
SIRT1 deacetylation and repression of p300 involves lysine residues 1020/1024 within the cell cycle regulatory domain 1. J Biol Chem (2005) 2.59
p53 post-translational modification: deregulated in tumorigenesis. Trends Mol Med (2010) 2.54
Brown remodeling of white adipose tissue by SirT1-dependent deacetylation of Pparγ. Cell (2012) 2.46
Structural basis of competitive recognition of p53 and MDM2 by HAUSP/USP7: implications for the regulation of the p53-MDM2 pathway. PLoS Biol (2006) 2.35
Nearly finished genomes produced using gel microdroplet culturing reveal substantial intraspecies genomic diversity within the human microbiome. Genome Res (2013) 2.29
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML. Blood (2006) 2.06
Microfluidics for flow cytometric analysis of cells and particles. Physiol Meas (2005) 2.00
Direct interactions between HIF-1 alpha and Mdm2 modulate p53 function. J Biol Chem (2003) 1.92
Hormonal control of androgen receptor function through SIRT1. Mol Cell Biol (2006) 1.91
Phosphorylation of Tip60 by GSK-3 determines the induction of PUMA and apoptosis by p53. Mol Cell (2011) 1.87
SIRT1 protects against emphysema via FOXO3-mediated reduction of premature senescence in mice. J Clin Invest (2012) 1.82
SnapShot: p53 posttranslational modifications. Cell (2008) 1.75
Suppression of cancer cell growth by promoting cyclin D1 degradation. Mol Cell (2009) 1.72
Transcription-independent ARF regulation in oncogenic stress-mediated p53 responses. Nature (2010) 1.71
Improving genome assemblies by sequencing PCR products with PacBio. Biotechniques (2012) 1.70
Computer-controlled microcirculatory support system for endothelial cell culture and shearing. Anal Chem (2005) 1.70
Differential effects on ARF stability by normal versus oncogenic levels of c-Myc expression. Mol Cell (2013) 1.67
Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways. Mol Cell Proteomics (2012) 1.54
α-adducin Gly460Trp polymorphism and essential hypertension risk in Chinese: a meta-analysis. Hypertens Res (2011) 1.51
p53 regulation by ubiquitin. FEBS Lett (2011) 1.51
p53-Dependent and p53-independent activation of autophagy by ARF. Cancer Res (2008) 1.50
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation. Genes Dev (2008) 1.50
Clinical relevance of the TLR4 11367 polymorphism in patients with major trauma. Arch Surg (2009) 1.42
Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer. Nat Cell Biol (2013) 1.36
ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription. Mol Cell Biol (2007) 1.35
Molecular characterization of propionyllysines in non-histone proteins. Mol Cell Proteomics (2008) 1.33
Dynamics in the p53-Mdm2 ubiquitination pathway. Cell Cycle (2004) 1.33
Fully human monoclonal antibodies antagonizing the glucagon receptor improve glucose homeostasis in mice and monkeys. J Pharmacol Exp Ther (2009) 1.29
Regulation of WRN protein cellular localization and enzymatic activities by SIRT1-mediated deacetylation. J Biol Chem (2008) 1.27
FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activity. J Biol Chem (2006) 1.26
Proatherogenic abnormalities of lipid metabolism in SirT1 transgenic mice are mediated through Creb deacetylation. Cell Metab (2011) 1.23
MSL2 promotes Mdm2-independent cytoplasmic localization of p53. J Biol Chem (2008) 1.21
Identification of a novel BRMS1-homologue protein p40 as a component of the mSin3A/p33(ING1b)/HDAC1 deacetylase complex. Biochem Biophys Res Commun (2004) 1.18
Mechanism of fast peptide recognition by SH3 domains. Angew Chem Int Ed Engl (2008) 1.17
Methyltransferase Set7/9 regulates p53 activity by interacting with Sirtuin 1 (SIRT1). Proc Natl Acad Sci U S A (2011) 1.17
Artificial polyploidy improves bacterial single cell genome recovery. PLoS One (2012) 1.10
Cyclophilin A binds to linear peptide motifs containing a consensus that is present in many human proteins. J Biol Chem (2005) 1.09
Involvement of CYR61 and CTGF in the fascin-mediated proliferation and invasiveness of esophageal squamous cell carcinomas cells. Am J Pathol (2010) 1.08
Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice. World J Gastroenterol (2007) 1.08
New insights into p53 activation. Cell Res (2010) 1.06
Identification and comparative analysis of the Eriocheir sinensis microRNA transcriptome response to Spiroplasma eriocheiris infection using a deep sequencing approach. Fish Shellfish Immunol (2011) 1.06
Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90. Proc Natl Acad Sci U S A (2011) 1.04
[Epidemiological survey of mental illnesses in the people aged 15 and older in Zhejiang Province, China]. Zhonghua Yu Fang Yi Xue Za Zhi (2005) 1.04
Potential roles of N-glycosylation in cell adhesion. Glycoconj J (2012) 1.04
Draft Genome Sequence of Methylomicrobium buryatense Strain 5G, a Haloalkaline-Tolerant Methanotrophic Bacterium. Genome Announc (2013) 1.04
Handheld recirculation system and customized media for microfluidic cell culture. Lab Chip (2005) 1.03
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressor. Mol Biol Cell (2008) 1.03
Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 4 targets MDM2 to deregulate the p53 tumor suppressor pathway. J Virol (2009) 1.03
Roles of N-acetylglucosaminyltransferase III in epithelial-to-mesenchymal transition induced by transforming growth factor β1 (TGF-β1) in epithelial cell lines. J Biol Chem (2012) 1.03
Monoubiquitination: the signal for p53 nuclear export? Cell Cycle (2004) 1.02
SIRT1-mediated acute cardioprotection. Am J Physiol Heart Circ Physiol (2011) 1.02
SIRT1: Regulator of p53 Deacetylation. Genes Cancer (2013) 1.01
Inactivation of arf-bp1 induces p53 activation and diabetic phenotypes in mice. J Biol Chem (2011) 1.00
To be, or not to be: functional dilemma of p53 metabolic regulation. Curr Opin Oncol (2014) 1.00
p53-mediated heterochromatin reorganization regulates its cell fate decisions. Nat Struct Mol Biol (2012) 1.00
Adhesive water networks facilitate binding of protein interfaces. Nat Commun (2011) 1.00
p53 Activation: a case against Sir. Cancer Cell (2008) 0.99
RFP-mediated ubiquitination of PTEN modulates its effect on AKT activation. Cell Res (2013) 0.98
Clinical relevance of the interleukin 10 promoter polymorphisms in Chinese Han patients with major trauma: genetic association studies. Crit Care (2009) 0.98
A critical role for noncoding 5S rRNA in regulating Mdmx stability. Mol Cell (2011) 0.98
RFWD3-Mdm2 ubiquitin ligase complex positively regulates p53 stability in response to DNA damage. Proc Natl Acad Sci U S A (2010) 0.98
An acyl-ghrelin-specific neutralizing antibody inhibits the acute ghrelin-mediated orexigenic effects in mice. Mol Pharmacol (2009) 0.97
RNA asymmetric distribution and daughter/mother differentiation in yeast. Curr Opin Microbiol (2003) 0.97
An oncogenic protein Golgi phosphoprotein 3 up-regulates cell migration via sialylation. J Biol Chem (2014) 0.96
Reduced membranous and ectopic cytoplasmic expression of DSC2 in esophageal squamous cell carcinoma: an independent prognostic factor. Hum Pathol (2010) 0.95
Identification of haplotype tag SNPs within the entire TLR2 gene and their clinical relevance in patients with major trauma. Shock (2011) 0.95
Mechanistic studies of MDM2-mediated ubiquitination in p53 regulation. J Biol Chem (2007) 0.94
Urinary proteomics as a novel tool for biomarker discovery in kidney diseases. J Zhejiang Univ Sci B (2010) 0.93
Flow cytometry analysis of glucocorticoid receptor expression and binding in steroid-sensitive and steroid-resistant patients with systemic lupus erythematosus. Arthritis Res Ther (2009) 0.92
Clinical relevance of IL-1beta promoter polymorphisms (-1470, -511, and -31) in patients with major trauma. Shock (2010) 0.92
Clinical observations on the association between diagnosis of lung cancer and serum tumor markers in combination. Asian Pac J Cancer Prev (2013) 0.92
Growth arrest and apoptosis of the human hepatocellular carcinoma cell line BEL-7402 induced by melittin. Onkologie (2006) 0.91